SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bb9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 10 ASP A 414
ILE A 365
GLY A 339
ILE A 341
VAL A 407
 None
 1.03A 1d4yA-4bb9A:
undetectable		 1d4yA-4bb9A:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 7 LEU A  74
SER A  78
THR A  82
VAL A  86
 None
 0.81A 1dvxB-4bb9A:
undetectable		 1dvxB-4bb9A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 7 ILE A 552
ARG A 553
PHE A   7
PHE A 516
 None
 1.12A 1e71M-4bb9A:
undetectable		 1e71M-4bb9A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 7 ILE A 552
ARG A 553
PHE A   7
PHE A 516
 None
 1.18A 1e72M-4bb9A:
undetectable		 1e72M-4bb9A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 ALA A 277
HIS A 278
VAL A 281
 None
 0.51A 1lqtB-4bb9A:
2.2		 1lqtB-4bb9A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 ALA A 277
HIS A 278
VAL A 281
 None
 0.51A 1lquB-4bb9A:
2.1		 1lquB-4bb9A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  53
VAL A 489
GLY A 492
ALA A 493
LEU A 497
 None
 1.03A 1pxxC-4bb9A:
undetectable		 1pxxC-4bb9A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 SER A 183
GLY A 181
ARG A 518
 F1P  A 702 ( 4.6A)
F1P  A 702 (-3.6A)
F1P  A 702 ( 4.2A)
 0.67A 1t9wA-4bb9A:
3.0		 1t9wA-4bb9A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 11 ALA A 435
SER A 458
LEU A 449
LEU A 445
THR A 411
 None
 1.21A 1tz8A-4bb9A:
undetectable
1tz8B-4bb9A:
undetectable		 1tz8A-4bb9A:
12.12
1tz8B-4bb9A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 202
GLU A  92
GLY A  88
ALA A  87
ALA A 276
 None
 1.16A 2br4B-4bb9A:
2.9		 2br4B-4bb9A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 THR A  31
PRO A 251
PRO A  29
 None
 0.89A 2d55C-4bb9A:
undetectable		 2d55C-4bb9A:
1.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 8 LEU A 416
GLN A 420
PHE A 410
LEU A 412
 None
 0.87A 2eilC-4bb9A:
undetectable
2eilJ-4bb9A:
undetectable		 2eilC-4bb9A:
18.12
2eilJ-4bb9A:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A 535
ALA A 574
LEU A 523
HIS A 560
PHE A   7
 None
 1.12A 2h77A-4bb9A:
undetectable		 2h77A-4bb9A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 227
VAL A 180
THR A  31
 None
F1P  A 702 (-3.8A)
None
 0.85A 2nnkA-4bb9A:
undetectable		 2nnkA-4bb9A:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 11 ALA A 287
LEU A 245
SER A 288
LEU A 292
LEU A  74
 None
 1.12A 2xn5A-4bb9A:
undetectable		 2xn5A-4bb9A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 6 LYS A 531
GLN A 524
GLY A 528
LEU A 579
 None
 1.09A 3bjwE-4bb9A:
undetectable		 3bjwE-4bb9A:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 4 ILE A 500
GLN A 502
ILE A  49
LEU A 605
 None
 1.28A 3dzyD-4bb9A:
undetectable		 3dzyD-4bb9A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 9 ASP A 414
ILE A 365
GLY A 339
ILE A 341
VAL A 407
 None
 1.02A 3ekyB-4bb9A:
undetectable		 3ekyB-4bb9A:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 6 GLY A 107
GLU A 153
GLU A 150
GLU A  32
 F1P  A 702 (-4.3A)
F1P  A 702 (-3.3A)
None
None
 1.04A 3fpjA-4bb9A:
3.3		 3fpjA-4bb9A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 LEU A 449
PRO A 448
LEU A 452
 None
 0.53A 3hcrA-4bb9A:
2.6		 3hcrA-4bb9A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 227
VAL A 180
THR A  31
 None
F1P  A 702 (-3.8A)
None
 0.85A 3k4vA-4bb9A:
undetectable		 3k4vA-4bb9A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 SER A 224
ASP A 192
ASN A 196
 None
 0.85A 3lsfB-4bb9A:
undetectable
3lsfE-4bb9A:
undetectable		 3lsfB-4bb9A:
17.34
3lsfE-4bb9A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 ASP A 192
ASN A 196
SER A 224
 None
 0.81A 3lsfB-4bb9A:
undetectable
3lsfE-4bb9A:
undetectable		 3lsfB-4bb9A:
17.34
3lsfE-4bb9A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 9 ASP A 414
ILE A 365
GLY A 339
ILE A 341
VAL A 407
 None
 1.10A 3ndwB-4bb9A:
undetectable		 3ndwB-4bb9A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 9 ILE A 313
LEU A 486
THR A 405
LEU A 497
GLY A 346
 None
 1.44A 3nxuB-4bb9A:
1.9		 3nxuB-4bb9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 9 ILE A 343
LEU A 378
PHE A 385
ARG A 358
GLY A 382
 None
 1.25A 3nxuB-4bb9A:
1.9		 3nxuB-4bb9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 591
VAL A 570
ALA A 574
SER A 577
LEU A 578
 None
 1.10A 4coxA-4bb9A:
4.6		 4coxA-4bb9A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 591
VAL A 570
ALA A 574
SER A 577
LEU A 578
 None
 1.11A 4coxD-4bb9A:
undetectable		 4coxD-4bb9A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 7 ILE A 219
ARG A 215
GLY A 181
ALA A 188
 None
None
F1P  A 702 (-3.6A)
None
 0.91A 4g0uB-4bb9A:
undetectable		 4g0uB-4bb9A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 4 SER A 490
GLY A 263
GLU A 271
 None
 0.50A 4juoA-4bb9A:
undetectable
4juoC-4bb9A:
3.1		 4juoA-4bb9A:
21.60
4juoC-4bb9A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 297
GLU A 294
PHE A 466
 None
 0.95A 4kszA-4bb9A:
undetectable		 4kszA-4bb9A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A 535
ALA A 574
LEU A 523
HIS A 560
PHE A   7
 None
 1.13A 4lnwA-4bb9A:
undetectable		 4lnwA-4bb9A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A 535
ALA A 574
LEU A 523
HIS A 560
PHE A   7
 None
 1.12A 4lnxA-4bb9A:
undetectable		 4lnxA-4bb9A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 9 ALA A 230
SER A 110
ILE A 178
GLY A 181
VAL A 187
 None
F1P  A 702 (-2.6A)
None
F1P  A 702 (-3.6A)
None
 1.06A 4r1zA-4bb9A:
undetectable		 4r1zA-4bb9A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 GLU A 424
LEU A 416
LEU A 397
ALA A 437
PHE A 453
 None
 1.30A 4retC-4bb9A:
4.8		 4retC-4bb9A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  53
VAL A 489
GLY A 492
ALA A 493
LEU A 497
 None
 1.01A 4rrxA-4bb9A:
undetectable		 4rrxA-4bb9A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  53
VAL A 489
GLY A 492
ALA A 493
LEU A 497
 None
 1.01A 4rrxB-4bb9A:
undetectable		 4rrxB-4bb9A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 7 LEU A 480
GLY A 263
GLY A 262
ILE A 249
 None
 0.64A 4yjiA-4bb9A:
undetectable		 4yjiA-4bb9A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 GLY A 442
LEU A 416
ILE A 422
GLY A 334
THR A 440
 None
 1.10A 4ze2A-4bb9A:
undetectable		 4ze2A-4bb9A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A 535
ALA A 574
LEU A 523
HIS A 560
PHE A   7
 None
 1.27A 4zo1X-4bb9A:
undetectable		 4zo1X-4bb9A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A 535
ARG A 533
ALA A 574
LEU A 523
PHE A   7
 None
 1.36A 4zo1X-4bb9A:
undetectable		 4zo1X-4bb9A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 THR A 337
ASP A 414
GLU A 418
 None
 0.84A 5fa8A-4bb9A:
undetectable		 5fa8A-4bb9A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 11 TYR A 136
ASP A 142
ILE A 340
PHE A 387
LEU A 378
 None
 1.34A 5huaA-4bb9A:
undetectable		 5huaA-4bb9A:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 5 TYR A 468
ILE A 285
LEU A 464
GLY A 470
PHE A 466
 None
 1.23A 5kmdC-4bb9A:
5.5
5kmdD-4bb9A:
2.7		 5kmdC-4bb9A:
17.98
5kmdD-4bb9A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
 None
 1.07A 5n0oA-4bb9A:
2.2		 5n0oA-4bb9A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
 None
 1.07A 5n0oB-4bb9A:
3.5		 5n0oB-4bb9A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
 None
 1.08A 5n0rA-4bb9A:
undetectable		 5n0rA-4bb9A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 4 SER A 288
ALA A 287
GLN A 283
THR A 280
 None
 1.45A 5n0rA-4bb9A:
undetectable		 5n0rA-4bb9A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
 None
 1.01A 5n0sA-4bb9A:
2.1		 5n0sA-4bb9A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
 None
 1.05A 5n0wA-4bb9A:
3.5		 5n0wA-4bb9A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
 None
 1.05A 5n0wB-4bb9A:
3.6		 5n0wB-4bb9A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 4 SER A 288
ALA A 287
GLN A 283
THR A 280
 None
 1.44A 5n0xA-4bb9A:
2.3		 5n0xA-4bb9A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
 None
 1.03A 5n4iA-4bb9A:
2.5		 5n4iA-4bb9A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  94
ALA A 277
LEU A 274
ILE A 174
ILE A 176
 None
 1.32A 5nm5B-4bb9A:
4.7		 5nm5B-4bb9A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 VAL A  90
ALA A 287
TYR A 134
ALA A  87
GLY A  88
 None
 1.37A 5tzoA-4bb9A:
undetectable		 5tzoA-4bb9A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 12 VAL A  90
ALA A 287
TYR A 134
ALA A  87
GLY A  88
 None
 1.34A 5tzoC-4bb9A:
undetectable		 5tzoC-4bb9A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 5 GLN A 420
VAL A 419
PRO A 448
THR A 411
 None
 1.46A 6cduA-4bb9A:
undetectable
6cduB-4bb9A:
undetectable		 6cduA-4bb9A:
18.75
6cduB-4bb9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 5 GLN A 420
VAL A 419
PRO A 448
THR A 411
 None
 1.49A 6cduI-4bb9A:
1.6
6cduJ-4bb9A:
2.3		 6cduI-4bb9A:
18.75
6cduJ-4bb9A:
18.75