SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bbo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 4bbo BLR5658 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 TRP A   5
THR A  58
TYR A  53
 GOL  A1114 (-3.8A)
GOL  A1114 ( 4.5A)
None
 1.13A 2a3aA-4bboA:
undetectable		 2a3aA-4bboA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 4bbo BLR5658 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 TRP A   5
THR A  58
TYR A  53
 GOL  A1114 (-3.8A)
GOL  A1114 ( 4.5A)
None
 1.16A 2a3aB-4bboA:
undetectable		 2a3aB-4bboA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 4bbo BLR5658 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 TRP A   5
THR A  58
TYR A  53
 GOL  A1114 (-3.8A)
GOL  A1114 ( 4.5A)
None
 1.16A 2a3bA-4bboA:
undetectable		 2a3bA-4bboA:
14.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 4bbo BLR5658 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 ASN A   9
SER A  13
TYR A  31
TRP A  75
 BTN  A1001 (-3.3A)
BTN  A1001 (-2.6A)
BTN  A1001 (-4.9A)
BTN  A1001 (-4.9A)
 0.23A 2uz2A-4bboA:
14.6		 2uz2A-4bboA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 4bbo BLR5658 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 TRP A   5
TRP A   7
THR A  83
 GOL  A1114 (-3.8A)
None
GOL  A1114 ( 4.6A)
 0.11A 4bboB-4bboA:
23.6		 4bboB-4bboA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 4bbo BLR5658 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 4 ASN A  80
ALA A  82
GLY A  84
THR A 110
 None
 0.21A 4bboC-4bboA:
23.3		 4bboC-4bboA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BBO_D_ACTD1113_0
(BLR5658 PROTEIN)		 4bbo BLR5658 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 4 TRP A   5
LEU A  51
LEU A  79
THR A  83
 GOL  A1114 (-3.8A)
None
None
GOL  A1114 ( 4.6A)
 0.27A 4bboD-4bboA:
14.9		 4bboD-4bboA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_C_PACC601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 4bbo BLR5658 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 TRP A  75
PHE A 109
ILE A  60
VAL A  64
VAL A  47
 BTN  A1001 (-4.9A)
None
None
None
None
 1.28A 4yfbC-4bboA:
undetectable		 4yfbC-4bboA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_F_PACF601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 4bbo BLR5658 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 TRP A  75
PHE A 109
ILE A  60
VAL A  64
VAL A  47
 BTN  A1001 (-4.9A)
None
None
None
None
 1.28A 4yfbF-4bboA:
undetectable		 4yfbF-4bboA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_I_PACI601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 4bbo BLR5658 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 TRP A  75
PHE A 109
ILE A  60
VAL A  64
VAL A  47
 BTN  A1001 (-4.9A)
None
None
None
None
 1.28A 4yfbI-4bboA:
undetectable		 4yfbI-4bboA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_L_PACL601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 4bbo BLR5658 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 TRP A  75
PHE A 109
ILE A  60
VAL A  64
VAL A  47
 BTN  A1001 (-4.9A)
None
None
None
None
 1.28A 4yfbL-4bboA:
undetectable		 4yfbL-4bboA:
12.71