SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bbw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.81A 1a4gA-4bbwA:
25.0		 1a4gA-4bbwA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.58A 1a4gA-4bbwA:
25.0		 1a4gA-4bbwA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.61A 1a4gB-4bbwA:
24.9		 1a4gB-4bbwA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 8 VAL A 234
HIS A 103
GLU A 526
ASP A 221
 None
 1.17A 1s3zA-4bbwA:
undetectable
1s3zB-4bbwA:
undetectable		 1s3zA-4bbwA:
14.31
1s3zB-4bbwA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 269
TRP A 290
ASP A 235
PRO A 273
 None
 1.01A 1th6A-4bbwA:
undetectable		 1th6A-4bbwA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 269
TRP A 290
ASP A 235
PRO A 273
 None
 1.01A 2armA-4bbwA:
undetectable		 2armA-4bbwA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.84A 2cmlA-4bbwA:
21.4		 2cmlA-4bbwA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.67A 2cmlA-4bbwA:
21.4		 2cmlA-4bbwA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.82A 2cmlB-4bbwA:
4.6		 2cmlB-4bbwA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.66A 2cmlB-4bbwA:
4.6		 2cmlB-4bbwA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.81A 2cmlC-4bbwA:
3.0		 2cmlC-4bbwA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.83A 2cmlD-4bbwA:
21.6		 2cmlD-4bbwA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.68A 2cmlD-4bbwA:
21.6		 2cmlD-4bbwA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.50A 2f0zA-4bbwA:
41.3		 2f0zA-4bbwA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F10_A_BCZA382_0
(SIALIDASE 2)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		7 / 12 ARG A 204
ILE A 205
ARG A 223
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.50A 2f10A-4bbwA:
40.8		 2f10A-4bbwA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 GLN A  30
PHE A 144
LEU A  78
VAL A  26
VAL A 167
 None
 1.38A 2g70A-4bbwA:
undetectable		 2g70A-4bbwA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 GLN A  30
PHE A 144
LEU A  78
VAL A  26
VAL A 167
 None
 1.41A 2g70B-4bbwA:
undetectable		 2g70B-4bbwA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.83A 2htqA-4bbwA:
6.4		 2htqA-4bbwA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A  42
LEU A  44
HIS A 186
 None
 0.75A 2q6fB-4bbwA:
undetectable		 2q6fB-4bbwA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA503_0
(CHORISMATE SYNTHASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 5 THR A 398
ARG A 415
ALA A 400
ARG A 422
 None
 1.36A 2qhfA-4bbwA:
undetectable		 2qhfA-4bbwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		3 / 3 PRO A  96
GLY A  81
TYR A  99
 None
 0.72A 2vouA-4bbwA:
undetectable		 2vouA-4bbwA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		3 / 3 PRO A  96
GLY A  81
TYR A  99
 None
 0.70A 2vouB-4bbwA:
undetectable		 2vouB-4bbwA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		3 / 3 PRO A  96
GLY A  81
TYR A  99
 None
 0.69A 2vouC-4bbwA:
undetectable		 2vouC-4bbwA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_1
(NEURAMINIDASE A)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		7 / 12 ARG A 204
ILE A 205
ASP A 221
ASP A 272
ARG A 415
ARG A 479
TYR A 510
 None
 0.48A 2ya7A-4bbwA:
45.7		 2ya7A-4bbwA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_1
(NEURAMINIDASE A)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		7 / 12 ARG A 204
ILE A 205
ASP A 221
ASP A 272
ARG A 415
ARG A 479
TYR A 510
 None
 0.49A 2ya7B-4bbwA:
45.5		 2ya7B-4bbwA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_1
(NEURAMINIDASE A)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		7 / 12 ARG A 204
ILE A 205
ASP A 221
ASP A 272
ARG A 415
ARG A 479
TYR A 510
 None
 0.46A 2ya7C-4bbwA:
44.2		 2ya7C-4bbwA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		7 / 12 ARG A 204
ILE A 205
ASP A 221
ASP A 272
ARG A 415
ARG A 479
TYR A 510
 None
 0.51A 2ya7D-4bbwA:
45.4		 2ya7D-4bbwA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.87A 3b7eA-4bbwA:
5.6		 3b7eA-4bbwA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.65A 3b7eA-4bbwA:
5.6		 3b7eA-4bbwA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.87A 3b7eB-4bbwA:
21.4		 3b7eB-4bbwA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.65A 3b7eB-4bbwA:
21.4		 3b7eB-4bbwA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_1
(SPERMIDINE SYNTHASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 4 LEU A 346
GLN A 347
ASP A 229
ASP A 221
 None
 1.05A 3bwcA-4bbwA:
0.0		 3bwcA-4bbwA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 GLN A 297
ASP A 229
LEU A 346
ALA A 299
SER A 302
 None
 1.20A 3d91B-4bbwA:
undetectable		 3d91B-4bbwA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.83A 3k39B-4bbwA:
24.9		 3k39B-4bbwA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_B_P77B204_1
(PROTEIN S100-A4)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 6 CYH A 176
GLU A 177
PHE A  47
PHE A  94
 None
 1.45A 3m0wB-4bbwA:
undetectable
3m0wJ-4bbwA:
undetectable		 3m0wB-4bbwA:
10.74
3m0wJ-4bbwA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.65A 3sanA-4bbwA:
12.0		 3sanA-4bbwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.66A 3sanB-4bbwA:
2.1		 3sanB-4bbwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.85A 3ti5A-4bbwA:
21.5		 3ti5A-4bbwA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.62A 3ti5A-4bbwA:
21.5		 3ti5A-4bbwA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.86A 3ti5B-4bbwA:
6.0		 3ti5B-4bbwA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.62A 3ti5B-4bbwA:
6.0		 3ti5B-4bbwA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.83A 3ticA-4bbwA:
8.1		 3ticA-4bbwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.65A 3ticA-4bbwA:
8.1		 3ticA-4bbwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.85A 3ticB-4bbwA:
21.6		 3ticB-4bbwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.82A 3ticC-4bbwA:
21.6		 3ticC-4bbwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.66A 3ticC-4bbwA:
21.6		 3ticC-4bbwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.83A 3ticD-4bbwA:
21.5		 3ticD-4bbwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.64A 3ticD-4bbwA:
21.5		 3ticD-4bbwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ABZ_A_T1CA1209_1
(TETRACYCLINE
REPRESSOR CLASS D)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 332
GLN A 311
THR A 312
GLN A 314
LEU A 263
 None
 1.24A 4abzA-4bbwA:
undetectable		 4abzA-4bbwA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.86A 4b7nA-4bbwA:
12.4		 4b7nA-4bbwA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.64A 4b7nA-4bbwA:
12.4		 4b7nA-4bbwA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.93A 4b7qA-4bbwA:
21.5		 4b7qA-4bbwA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.69A 4b7qA-4bbwA:
21.5		 4b7qA-4bbwA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.88A 4b7qB-4bbwA:
21.5		 4b7qB-4bbwA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.86A 4b7qC-4bbwA:
12.9		 4b7qC-4bbwA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.62A 4b7qC-4bbwA:
12.9		 4b7qC-4bbwA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.87A 4b7qD-4bbwA:
12.4		 4b7qD-4bbwA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 237
ASP A 235
VAL A 222
MET A 251
 None
 0.84A 4c5nA-4bbwA:
undetectable		 4c5nA-4bbwA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.83A 4cpnA-4bbwA:
25.0		 4cpnA-4bbwA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.64A 4cpnA-4bbwA:
25.0		 4cpnA-4bbwA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.85A 4cpnB-4bbwA:
5.9		 4cpnB-4bbwA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.63A 4cpnB-4bbwA:
5.9		 4cpnB-4bbwA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.65A 4cpzA-4bbwA:
24.9		 4cpzA-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.62A 4cpzB-4bbwA:
25.0		 4cpzB-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.88A 4cpzC-4bbwA:
25.0		 4cpzC-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.62A 4cpzC-4bbwA:
25.0		 4cpzC-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.59A 4cpzD-4bbwA:
25.1		 4cpzD-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.91A 4cpzE-4bbwA:
8.8		 4cpzE-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.65A 4cpzE-4bbwA:
8.8		 4cpzE-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.90A 4cpzF-4bbwA:
25.0		 4cpzF-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.66A 4cpzF-4bbwA:
25.0		 4cpzF-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.83A 4cpzG-4bbwA:
25.1		 4cpzG-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.63A 4cpzG-4bbwA:
25.1		 4cpzG-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.77A 4cpzH-4bbwA:
24.9		 4cpzH-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.71A 4cpzH-4bbwA:
24.9		 4cpzH-4bbwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A 353
LEU A 276
LYS A 385
GLY A 384
 None
 0.90A 4hbfA-4bbwA:
undetectable		 4hbfA-4bbwA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.83A 4i00A-4bbwA:
21.5		 4i00A-4bbwA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.64A 4i00A-4bbwA:
21.5		 4i00A-4bbwA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 346
ALA A 313
LEU A 345
THR A 312
 None
 1.13A 4iklA-4bbwA:
1.1
4iklB-4bbwA:
undetectable		 4iklA-4bbwA:
13.12
4iklB-4bbwA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		3 / 4 SER A 200
GLY A 271
GLU A 399
 None
 0.52A 4juoA-4bbwA:
undetectable
4juoC-4bbwA:
undetectable		 4juoA-4bbwA:
21.55
4juoC-4bbwA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 9 ASP A 243
PHE A 534
LEU A 156
LEU A 216
ASP A 517
 None
 1.32A 4qopA-4bbwA:
undetectable		 4qopA-4bbwA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_B_HQEB503_1
(CATALASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 9 ASP A 243
PHE A 534
LEU A 156
LEU A 216
ASP A 517
 None
 1.32A 4qopB-4bbwA:
undetectable		 4qopB-4bbwA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		6 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 1.19A 4wa5A-4bbwA:
22.1		 4wa5A-4bbwA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 11 THR A 386
SER A 380
GLY A 384
ASP A 278
THR A 354
 None
 1.35A 4xt7A-4bbwA:
undetectable		 4xt7A-4bbwA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_A_5D5A930_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 323
THR A 215
LEU A 217
ILE A 205
TRP A 285
 None
 1.26A 5dlvA-4bbwA:
undetectable		 5dlvA-4bbwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A  79
LYS A 118
GLU A 121
SER A 147
 None
 1.31A 5jhdJ-4bbwA:
undetectable		 5jhdJ-4bbwA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A 258
GLU A 259
PHE A 257
TYR A 233
 None
 0.87A 5kmfA-4bbwA:
undetectable
5kmfC-4bbwA:
undetectable		 5kmfA-4bbwA:
19.89
5kmfC-4bbwA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
ASP A 229
GLU A 399
ARG A 415
TYR A 510
 None
 0.83A 5l17A-4bbwA:
21.4		 5l17A-4bbwA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 204
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.65A 5l17A-4bbwA:
21.4		 5l17A-4bbwA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 5 THR A 359
GLU A 404
THR A 405
HIS A 437
 None
 1.23A 5utuH-4bbwA:
undetectable		 5utuH-4bbwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A  99
TYR A  79
GLY A  81
GLY A  82
 None
 1.06A 5x7pA-4bbwA:
2.1		 5x7pA-4bbwA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 6 SER A 511
ARG A 204
GLU A 526
TYR A 510
 None
 1.26A 5x7pB-4bbwA:
2.2		 5x7pB-4bbwA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 218
GLY A 522
ILE A 516
VAL A 190
VAL A 192
 None
 1.04A 6dh0B-4bbwA:
undetectable		 6dh0B-4bbwA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		7 / 12 ARG A 204
ILE A 205
ARG A 223
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.49A 6ekuA-4bbwA:
43.0		 6ekuA-4bbwA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		7 / 12 ARG A 204
ILE A 205
ASP A 272
GLU A 399
ARG A 415
ARG A 479
TYR A 510
 None
 0.74A 6ekuA-4bbwA:
43.0		 6ekuA-4bbwA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 156
GLY A 207
LEU A 216
GLY A 245
 None
 0.65A 6eu9D-4bbwA:
undetectable		 6eu9D-4bbwA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 4bbw SIALIDASE
(NEURAMINIDASE)
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 420
GLY A 419
GLY A 509
PRO A 206
GLU A 526
 None
 1.05A 6gngB-4bbwA:
undetectable		 6gngB-4bbwA:
21.71