SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bct'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4bct THAUMATIN-LIKE
PROTEIN
(Actinidia
deliciosa) 		3 / 3 ASP A  77
ARG A  81
ALA A  79
 None
 0.78A 3mbgC-4bctA:
undetectable		 3mbgC-4bctA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 4bct THAUMATIN-LIKE
PROTEIN
(Actinidia
deliciosa) 		4 / 8 ASN A  90
GLN A 100
ASN A 103
THR A  86
 None
 1.40A 4d1yA-4bctA:
undetectable
4d1yB-4bctA:
undetectable		 4d1yA-4bctA:
21.85
4d1yB-4bctA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4bct THAUMATIN-LIKE
PROTEIN
(Actinidia
deliciosa) 		5 / 12 PHE A  27
ASN A  54
ILE A  29
ALA A  41
VAL A  68
 None
 1.19A 4dx5B-4bctA:
undetectable		 4dx5B-4bctA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4bct THAUMATIN-LIKE
PROTEIN
(Actinidia
deliciosa) 		5 / 9 THR A  72
ALA A 130
GLY A 162
GLY A 163
ASP A 149
 None
 0.99A 4qwuY-4bctA:
undetectable
4qwuZ-4bctA:
undetectable		 4qwuY-4bctA:
20.25
4qwuZ-4bctA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4bct THAUMATIN-LIKE
PROTEIN
(Actinidia
deliciosa) 		4 / 8 THR A 104
ALA A 199
ASP A 205
SER A 209
 None
 1.10A 5l5fY-4bctA:
undetectable
5l5fZ-4bctA:
undetectable		 5l5fY-4bctA:
18.58
5l5fZ-4bctA:
20.60