SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bdu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 4bdu GREEN FLUORESCENT
PROTEIN, APOPTOSIS
REGULATOR BAX
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 ASN A 170
LEU A 141
HIS A 169
 None
 0.86A 2q6fB-4bduA:
undetectable		 2q6fB-4bduA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 4bdu GREEN FLUORESCENT
PROTEIN, APOPTOSIS
REGULATOR BAX
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 TYR A 106
ASP A 103
HIS A 139
 None
 0.89A 3e23A-4bduA:
undetectable		 3e23A-4bduA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 4bdu GREEN FLUORESCENT
PROTEIN, APOPTOSIS
REGULATOR BAX
(Aequorea
victoria;
Homo
sapiens) 		5 / 11 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CR2  A  65 ( 4.3A)
None
None
 1.17A 3t3rA-4bduA:
undetectable		 3t3rA-4bduA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4bdu GREEN FLUORESCENT
PROTEIN, APOPTOSIS
REGULATOR BAX
(Aequorea
victoria;
Homo
sapiens) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CR2  A  65 ( 4.3A)
None
None
 1.14A 3t3rB-4bduA:
undetectable		 3t3rB-4bduA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4bdu GREEN FLUORESCENT
PROTEIN, APOPTOSIS
REGULATOR BAX
(Aequorea
victoria;
Homo
sapiens) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CR2  A  65 ( 4.3A)
None
None
 1.18A 3t3rC-4bduA:
undetectable		 3t3rC-4bduA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4bdu GREEN FLUORESCENT
PROTEIN, APOPTOSIS
REGULATOR BAX
(Aequorea
victoria;
Homo
sapiens) 		5 / 10 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CR2  A  65 ( 4.3A)
None
None
 1.13A 3t3rD-4bduA:
undetectable		 3t3rD-4bduA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4bdu GREEN FLUORESCENT
PROTEIN, APOPTOSIS
REGULATOR BAX
(Aequorea
victoria;
Homo
sapiens) 		4 / 8 GLY A  10
GLY A  35
LEU A  42
TYR A  39
 None
 0.90A 4fgzB-4bduA:
undetectable		 4fgzB-4bduA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 4bdu GREEN FLUORESCENT
PROTEIN, APOPTOSIS
REGULATOR BAX
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 VAL A  22
GLY A  24
LYS A  26
 None
 0.77A 4k50E-4bduA:
undetectable		 4k50E-4bduA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4bdu GREEN FLUORESCENT
PROTEIN, APOPTOSIS
REGULATOR BAX
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 HIS A 148
ILE A 161
PHE A  84
THR A  63
THR A  62
 CR2  A  65 ( 4.3A)
None
None
None
None
 1.20A 6bbsA-4bduA:
undetectable		 6bbsA-4bduA:
13.73