SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4beg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 4beg PHOSPHATIDYLETHANOLA
MINE BINDING PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 144
ALA A  83
ALA A  63
THR A  65
LEU A  14
 None
None
None
None
GOL  A1178 (-4.5A)
 1.08A 1cbsA-4begA:
undetectable		 1cbsA-4begA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 4beg PHOSPHATIDYLETHANOLA
MINE BINDING PROTEIN
(Mycobacterium
tuberculosis) 		4 / 4 LEU A 155
SER A  61
LEU A 107
LEU A 146
 None
 1.17A 1yajA-4begA:
undetectable		 1yajA-4begA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 4beg PHOSPHATIDYLETHANOLA
MINE BINDING PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 TYR A 133
VAL A 129
HIS A 130
ARG A 131
 None
 1.24A 3b9lA-4begA:
undetectable		 3b9lA-4begA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 4beg PHOSPHATIDYLETHANOLA
MINE BINDING PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 103
GLY A 105
ALA A 106
ALA A  63
 None
 0.88A 3ur0B-4begA:
undetectable		 3ur0B-4begA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 4beg PHOSPHATIDYLETHANOLA
MINE BINDING PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 ALA A  81
LEU A 109
VAL A 110
ASP A 112
 None
 0.96A 4g24A-4begA:
undetectable		 4g24A-4begA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4beg PHOSPHATIDYLETHANOLA
MINE BINDING PROTEIN
(Mycobacterium
tuberculosis) 		4 / 5 PHE A 160
HIS A 162
PHE A 157
LEU A 144
 None
 1.34A 4o8zA-4begA:
undetectable		 4o8zA-4begA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 4beg PHOSPHATIDYLETHANOLA
MINE BINDING PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 131
PRO A   5
TYR A  67
 None
 0.76A 5tzoB-4begA:
undetectable		 5tzoB-4begA:
24.20