SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bej'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 9 THR A 288
GLY A 281
LEU A 285
ARG A 279
GLY A 243
 None
 1.30A 1jhoA-4bejA:
undetectable		 1jhoA-4bejA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 9 THR A 288
GLY A 281
LEU A 285
ARG A 279
GLY A 243
 None
 1.28A 1jhyA-4bejA:
undetectable		 1jhyA-4bejA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 ILE A 701
GLN A  12
LEU A 304
LEU A 293
ILE A 297
 None
 1.33A 1kqwA-4bejA:
undetectable		 1kqwA-4bejA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 9 THR A 288
GLY A 281
LEU A 285
ARG A 279
GLY A 243
 None
 1.30A 1l4nA-4bejA:
undetectable		 1l4nA-4bejA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 9 THR A 288
GLY A 281
LEU A 285
ARG A 279
GLY A 243
 None
 1.28A 1l5kA-4bejA:
undetectable		 1l5kA-4bejA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 9 THR A 288
GLY A 281
LEU A 285
ARG A 279
GLY A 243
 None
 1.30A 1l5lA-4bejA:
undetectable		 1l5lA-4bejA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 7 GLY A 240
ILE A 235
VAL A 237
PRO A 236
 None
 1.08A 1rxcF-4bejA:
undetectable		 1rxcF-4bejA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		3 / 3 SER A 428
VAL A 381
LEU A 378
 None
 0.73A 1yajG-4bejA:
undetectable		 1yajG-4bejA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 670
LEU A 669
VAL A 661
LEU A 334
THR A 332
 None
 1.24A 2q7kA-4bejA:
undetectable		 2q7kA-4bejA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 7 TYR A 273
ASN A 280
GLY A 281
VAL A 245
 None
 0.91A 2y05A-4bejA:
undetectable
2y05B-4bejA:
undetectable		 2y05A-4bejA:
20.20
2y05B-4bejA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 6 THR A 259
VAL A 258
GLU A 265
SER A  44
 None
 1.09A 3b6rB-4bejA:
undetectable		 3b6rB-4bejA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 6 ILE A 199
ALA A 196
ALA A 212
THR A 210
 None
 1.01A 3mdrB-4bejA:
undetectable		 3mdrB-4bejA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 6 LEU A 624
SER A 627
TYR A 628
ALA A 504
 None
 0.59A 3ravA-4bejA:
2.9		 3ravA-4bejA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 6 LEU A 624
SER A 627
TYR A 628
ALA A 504
 None
 0.59A 3rd0A-4bejA:
3.0		 3rd0A-4bejA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 LYS A 418
LEU A 416
ALA A 395
ALA A 399
ILE A 392
 None
 1.22A 3ut5D-4bejA:
3.2		 3ut5D-4bejA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 269
GLY A 281
ILE A 214
VAL A 213
 None
 0.85A 3wriA-4bejA:
undetectable		 3wriA-4bejA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 269
GLY A 281
ILE A 214
VAL A 213
 None
 0.85A 3wriB-4bejA:
undetectable		 3wriB-4bejA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 269
GLY A 281
ILE A 214
VAL A 213
 None
 0.89A 3wrkA-4bejA:
undetectable		 3wrkA-4bejA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 8 SER A 428
ILE A 636
LEU A 491
ILE A 421
 None
 0.92A 4dtaB-4bejA:
2.7		 4dtaB-4bejA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 461
SER A 447
ILE A 443
LEU A 660
PHE A 340
 None
 1.41A 4foxE-4bejA:
undetectable		 4foxE-4bejA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 9 THR A 288
GLY A 281
LEU A 285
ARG A 279
GLY A 243
 None
 1.29A 4kqiA-4bejA:
undetectable		 4kqiA-4bejA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 144
ILE A 180
ILE A 242
VAL A  30
ILE A  28
 None
 0.99A 4q1yB-4bejA:
undetectable		 4q1yB-4bejA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 5 LEU A  67
ALA A 286
THR A 282
VAL A 258
ILE A 262
 None
 1.11A 4xe3A-4bejA:
undetectable		 4xe3A-4bejA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 5 LEU A  67
ALA A 286
THR A 282
VAL A 258
ILE A 262
 None
 1.15A 4xe3B-4bejA:
3.7		 4xe3B-4bejA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 10 PRO A 177
LEU A 304
ILE A 308
ALA A 697
PHE A  15
 None
 1.30A 5m0oA-4bejA:
undetectable		 5m0oA-4bejA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 8 LEU A 304
ILE A 308
ALA A 697
PHE A  15
 None
 0.87A 5m0oC-4bejA:
undetectable		 5m0oC-4bejA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 ILE A 214
THR A  33
SER A  36
LEU A 285
LEU A 289
 None
 1.21A 5nfjB-4bejA:
undetectable		 5nfjB-4bejA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 ILE A 214
THR A  33
SER A  36
LEU A 289
LEU A 211
 None
 1.17A 5nfjB-4bejA:
undetectable		 5nfjB-4bejA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 ILE A 214
THR A  33
SER A  36
LEU A 285
LEU A 289
 None
 1.25A 5nfjC-4bejA:
undetectable		 5nfjC-4bejA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 PHE A  15
ALA A 693
ILE A 701
ILE A 700
LEU A 304
 None
 1.29A 5uanB-4bejA:
undetectable		 5uanB-4bejA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 4bej DYNAMIN 1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 5 ASN A 650
TYR A 344
VAL A 468
LEU A 660
 None
 1.29A 6a7pA-4bejA:
2.4		 6a7pA-4bejA:
22.80