SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bfc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 4bfc 3-DEOXY-D-MANNO-OCTU
LOSONIC-ACID
TRANSFERASE
(Acinetobacter
baumannii) 		5 / 12 VAL A 308
VAL A 384
LEU A 261
LEU A 257
LEU A 388
 None
 1.42A 1mx1E-4bfcA:
undetectable		 1mx1E-4bfcA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4bfc 3-DEOXY-D-MANNO-OCTU
LOSONIC-ACID
TRANSFERASE
(Acinetobacter
baumannii) 		4 / 7 TRP A 320
GLN A 231
TYR A 309
ILE A 270
 None
 1.00A 2ph9A-4bfcA:
undetectable
2ph9B-4bfcA:
undetectable		 2ph9A-4bfcA:
21.03
2ph9B-4bfcA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 4bfc 3-DEOXY-D-MANNO-OCTU
LOSONIC-ACID
TRANSFERASE
(Acinetobacter
baumannii) 		3 / 3 ARG A 296
SER A 313
TYR A 309
 None
 0.98A 2q2hA-4bfcA:
undetectable
2q2hB-4bfcA:
undetectable		 2q2hA-4bfcA:
21.58
2q2hB-4bfcA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4bfc 3-DEOXY-D-MANNO-OCTU
LOSONIC-ACID
TRANSFERASE
(Acinetobacter
baumannii) 		5 / 12 VAL A 384
VAL A 282
LEU A 310
ILE A 285
THR A 293
 None
 1.41A 3elzA-4bfcA:
undetectable		 3elzA-4bfcA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4bfc 3-DEOXY-D-MANNO-OCTU
LOSONIC-ACID
TRANSFERASE
(Acinetobacter
baumannii) 		4 / 6 TYR A 321
GLY A 330
THR A 241
GLU A 249
 None
 1.07A 3fpjA-4bfcA:
4.7		 3fpjA-4bfcA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 4bfc 3-DEOXY-D-MANNO-OCTU
LOSONIC-ACID
TRANSFERASE
(Acinetobacter
baumannii) 		4 / 6 GLN A 252
LEU A 254
GLU A 255
LEU A 289
 None
 0.75A 3h5gA-4bfcA:
undetectable
3h5gC-4bfcA:
undetectable		 3h5gA-4bfcA:
7.96
3h5gC-4bfcA:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 4bfc 3-DEOXY-D-MANNO-OCTU
LOSONIC-ACID
TRANSFERASE
(Acinetobacter
baumannii) 		4 / 6 LEU A 289
GLN A 252
LEU A 254
GLU A 255
 None
 1.04A 3h5gB-4bfcA:
undetectable
3h5gC-4bfcA:
undetectable		 3h5gB-4bfcA:
7.96
3h5gC-4bfcA:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4bfc 3-DEOXY-D-MANNO-OCTU
LOSONIC-ACID
TRANSFERASE
(Acinetobacter
baumannii) 		4 / 8 LEU A 319
LYS A 218
TRP A 232
LEU A 323
 None
 1.09A 3v81A-4bfcA:
undetectable		 3v81A-4bfcA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4bfc 3-DEOXY-D-MANNO-OCTU
LOSONIC-ACID
TRANSFERASE
(Acinetobacter
baumannii) 		4 / 5 GLY A 337
GLY A 338
ASN A 360
GLU A 335
 None
 1.16A 4fglC-4bfcA:
3.9		 4fglC-4bfcA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 4bfc 3-DEOXY-D-MANNO-OCTU
LOSONIC-ACID
TRANSFERASE
(Acinetobacter
baumannii) 		4 / 8 LEU A 319
LYS A 218
TRP A 232
LEU A 323
 None
 1.08A 4q0bA-4bfcA:
undetectable		 4q0bA-4bfcA:
15.14