SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bfi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4bfi OX-2 MEMBRANE
GLYCOPROTEIN
(Mus
musculus) 		3 / 3 GLN B  35
THR B  47
ASN B  44
 None
 0.90A 3v4tE-4bfiB:
undetectable		 3v4tE-4bfiB:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 4bfi OX-2 MEMBRANE
GLYCOPROTEIN
(Mus
musculus) 		4 / 5 HIS B 116
SER B 131
SER B 164
VAL B 165
 None
 1.27A 4a99D-4bfiB:
undetectable		 4a99D-4bfiB:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 4bfi OX-2 MEMBRANE
GLYCOPROTEIN
(Mus
musculus) 		4 / 7 LEU B  69
SER B  75
THR B  77
SER B  18
 None
 1.03A 4iklA-4bfiB:
undetectable
4iklB-4bfiB:
3.6		 4iklA-4bfiB:
23.37
4iklB-4bfiB:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4bfi OX-2 MEMBRANE
GLYCOPROTEIN
(Mus
musculus) 		4 / 6 ILE B 168
GLY B 144
ILE B 128
TRP B 142
 NAG  B1270 ( 4.9A)
None
None
None
 0.87A 5j4nB-4bfiB:
undetectable		 5j4nB-4bfiB:
16.81