SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bg0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		5 / 12 PHE A 200
ALA A 167
ALA A 156
VAL A 126
LEU A 207
 None
 1.23A 1cbrA-4bg0A:
undetectable		 1cbrA-4bg0A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		5 / 12 PHE A 200
ALA A 167
ALA A 156
VAL A 126
LEU A 207
 None
 1.23A 1cbrB-4bg0A:
undetectable		 1cbrB-4bg0A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		5 / 11 PHE A 145
ILE A 184
ALA A 204
LEU A 207
ALA A 148
 None
 1.48A 1jb0B-4bg0A:
undetectable		 1jb0B-4bg0A:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		5 / 12 MET A 178
LEU A 207
ILE A 171
SER A 132
PHE A 133
 None
 1.21A 1xotA-4bg0A:
undetectable		 1xotA-4bg0A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		4 / 7 GLY A  38
THR A  37
TYR A  33
ASP A  42
 None
 1.05A 2g70A-4bg0A:
undetectable		 2g70A-4bg0A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		4 / 7 GLY A  38
THR A  37
TYR A  33
ASP A  42
 None
 1.04A 2g70B-4bg0A:
undetectable		 2g70B-4bg0A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		5 / 12 PHE A  18
LEU A 165
LEU A 168
ILE A  32
ALA A  31
 None
 1.01A 2v0mC-4bg0A:
undetectable		 2v0mC-4bg0A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		4 / 8 ILE A 130
ALA A 156
PHE A 200
ALA A 203
 None
 0.92A 3hrdA-4bg0A:
undetectable
3hrdB-4bg0A:
1.8		 3hrdA-4bg0A:
20.73
3hrdB-4bg0A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		4 / 8 ILE A 130
ALA A 156
PHE A 200
ALA A 204
 None
 0.87A 3hrdA-4bg0A:
undetectable
3hrdB-4bg0A:
1.8		 3hrdA-4bg0A:
20.73
3hrdB-4bg0A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		3 / 3 ASP A 116
ARG A 112
ALA A 115
 None
 0.71A 3mbgC-4bg0A:
3.5		 3mbgC-4bg0A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		5 / 11 PHE A 145
ILE A 184
ALA A 204
LEU A 207
ALA A 148
 None
 1.48A 3pcqB-4bg0A:
undetectable		 3pcqB-4bg0A:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		5 / 12 ILE A 136
ILE A 184
ALA A 204
LEU A 207
ALA A 148
 None
 1.13A 5oy02-4bg0A:
3.9		 5oy02-4bg0A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		5 / 10 PHE A 145
ILE A 184
ALA A 204
LEU A 207
ALA A 148
 None
 1.46A 5oy0b-4bg0A:
undetectable		 5oy0b-4bg0A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)
(Borreliella
burgdorferi) 		5 / 10 ILE A 136
ILE A 184
ALA A 204
LEU A 207
ALA A 148
 None
 1.15A 5zjiB-4bg0A:
undetectable		 5zjiB-4bg0A:
14.95