SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bg2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 PHE A  27
VAL A  29
TYR A  67
GLY A  65
 None
 0.82A 11gsA-4bg2A:
undetectable		 11gsA-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4bg2 PATF
(Prochloron
didemni) 		5 / 11 ASP A 305
SER A  50
ASN A  72
GLY A  74
THR A  76
 None
 1.29A 1jr1A-4bg2A:
undetectable		 1jr1A-4bg2A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 4bg2 PATF
(Prochloron
didemni) 		3 / 3 ALA A 110
VAL A 112
TRP A  77
 None
 0.87A 1nt6A-4bg2A:
undetectable		 1nt6A-4bg2A:
3.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 4bg2 PATF
(Prochloron
didemni) 		3 / 3 ALA A 110
VAL A 112
TRP A  77
 None
 0.87A 1nt6B-4bg2A:
undetectable		 1nt6B-4bg2A:
3.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 4bg2 PATF
(Prochloron
didemni) 		5 / 11 PHE A 245
MET A 136
LEU A 191
HIS A 125
TYR A 300
 None
 1.46A 1qabE-4bg2A:
2.2		 1qabE-4bg2A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 TYR A 301
TYR A 300
CYH A 298
HIS A  23
 None
 1.17A 1yvmA-4bg2A:
undetectable		 1yvmA-4bg2A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 VAL A  51
SER A  53
LEU A  17
THR A  22
 None
 1.16A 2f78A-4bg2A:
undetectable		 2f78A-4bg2A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 PHE A  27
VAL A  29
TYR A  67
GLY A  65
 None
 0.77A 2gssA-4bg2A:
undetectable		 2gssA-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 VAL A  29
ARG A  21
TYR A  67
GLY A  65
 None
 0.95A 2gssA-4bg2A:
undetectable		 2gssA-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 PHE A  27
VAL A  29
TYR A  67
GLY A  65
 None
 0.76A 2gssB-4bg2A:
undetectable		 2gssB-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 VAL A  29
ARG A  21
TYR A  67
GLY A  65
 None
 0.95A 2gssB-4bg2A:
undetectable		 2gssB-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4bg2 PATF
(Prochloron
didemni) 		4 / 6 TYR A 247
CYH A 298
TYR A 300
ILE A 243
 None
 1.22A 2xz5A-4bg2A:
undetectable
2xz5B-4bg2A:
undetectable		 2xz5A-4bg2A:
19.70
2xz5B-4bg2A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 TYR A 247
CYH A 298
TYR A 300
ILE A 243
 None
 1.22A 2xz5B-4bg2A:
undetectable
2xz5E-4bg2A:
undetectable		 2xz5B-4bg2A:
19.70
2xz5E-4bg2A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 ILE A 243
TYR A 247
CYH A 298
TYR A 300
 None
 1.22A 2xz5A-4bg2A:
undetectable
2xz5C-4bg2A:
undetectable		 2xz5A-4bg2A:
19.70
2xz5C-4bg2A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 ILE A 243
TYR A 247
CYH A 298
TYR A 300
 None
 1.22A 2xz5C-4bg2A:
undetectable
2xz5D-4bg2A:
undetectable		 2xz5C-4bg2A:
19.70
2xz5D-4bg2A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 ILE A 243
TYR A 247
CYH A 298
TYR A 300
 None
 1.22A 2xz5D-4bg2A:
undetectable
2xz5E-4bg2A:
undetectable		 2xz5D-4bg2A:
19.70
2xz5E-4bg2A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 PHE A  27
VAL A  29
TYR A  67
GLY A  65
 None
 0.73A 3gssA-4bg2A:
undetectable		 3gssA-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 PHE A  27
VAL A  29
TYR A  67
GLY A  65
 None
 0.73A 3gssB-4bg2A:
undetectable		 3gssB-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4bg2 PATF
(Prochloron
didemni) 		3 / 3 PRO A  31
LEU A  35
GLN A  24
 None
 0.73A 3hznG-4bg2A:
undetectable
3hznH-4bg2A:
0.6		 3hznG-4bg2A:
20.13
3hznH-4bg2A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4bg2 PATF
(Prochloron
didemni) 		3 / 3 ARG A  12
THR A  22
THR A 278
 None
 0.51A 3k2hB-4bg2A:
undetectable		 3k2hB-4bg2A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 PHE A  27
VAL A  29
TYR A  67
GLY A  65
 None
 0.80A 3n9jA-4bg2A:
undetectable		 3n9jA-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 VAL A  29
ARG A  21
TYR A  67
GLY A  65
 None
 0.95A 3n9jA-4bg2A:
undetectable		 3n9jA-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 PHE A  27
VAL A  29
TYR A  67
GLY A  65
 None
 0.80A 3n9jB-4bg2A:
undetectable		 3n9jB-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 4bg2 PATF
(Prochloron
didemni) 		3 / 3 PHE A  19
SER A  53
GLN A 303
 None
 1.00A 3smtA-4bg2A:
undetectable		 3smtA-4bg2A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 ILE A 141
SER A 103
LEU A 191
VAL A 189
 None
 0.85A 3ua5B-4bg2A:
undetectable		 3ua5B-4bg2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 GLU A  52
TYR A  67
GLY A  64
ARG A  66
 None
 1.04A 4fgzA-4bg2A:
undetectable		 4fgzA-4bg2A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 GLU A  52
TYR A  67
GLY A  64
ARG A  66
 None
 0.91A 4fgzA-4bg2A:
undetectable
4fgzB-4bg2A:
undetectable		 4fgzA-4bg2A:
22.74
4fgzB-4bg2A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 4bg2 PATF
(Prochloron
didemni) 		3 / 3 ASP A 279
TYR A 247
TRP A 304
 None
 1.44A 4p7nA-4bg2A:
undetectable		 4p7nA-4bg2A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 PHE A  19
SER A  50
THR A 278
TYR A 247
 None
 1.39A 4qb9D-4bg2A:
0.7		 4qb9D-4bg2A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 ARG A 239
ASP A 190
TYR A 138
TYR A 300
 None
 1.47A 5a06A-4bg2A:
undetectable		 5a06A-4bg2A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 ARG A 239
ASP A 190
TYR A 138
TYR A 300
 None
 1.48A 5a06C-4bg2A:
undetectable		 5a06C-4bg2A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 ARG A 239
ASP A 190
TYR A 138
TYR A 300
 None
 1.49A 5a06D-4bg2A:
undetectable		 5a06D-4bg2A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 ARG A 239
ASP A 190
TYR A 138
TYR A 300
 None
 1.47A 5a06E-4bg2A:
undetectable		 5a06E-4bg2A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4bg2 PATF
(Prochloron
didemni) 		4 / 7 ARG A 239
ASP A 190
TYR A 138
TYR A 300
 None
 1.46A 5a06F-4bg2A:
undetectable		 5a06F-4bg2A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 4bg2 PATF
(Prochloron
didemni) 		5 / 12 PHE A  85
PHE A 104
PHE A 107
ALA A 110
LEU A 150
 None
 1.20A 5iepA-4bg2A:
undetectable		 5iepA-4bg2A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4bg2 PATF
(Prochloron
didemni) 		5 / 12 HIS A 140
GLU A 180
ALA A 108
SER A 236
PHE A 234
 None
 1.34A 5iwuA-4bg2A:
undetectable		 5iwuA-4bg2A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4bg2 PATF
(Prochloron
didemni) 		5 / 12 GLU A 241
GLU A 180
HIS A 125
PHE A 245
GLY A 178
 None
 1.43A 5xioA-4bg2A:
undetectable		 5xioA-4bg2A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4bg2 PATF
(Prochloron
didemni) 		4 / 8 GLU A  52
HIS A 140
PHE A 179
PHE A 104
 None
 1.02A 5y2tB-4bg2A:
undetectable		 5y2tB-4bg2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 4bg2 PATF
(Prochloron
didemni) 		4 / 6 LEU A  87
LEU A 181
THR A 121
ARG A 239
 None
 1.04A 6ew0G-4bg2A:
undetectable		 6ew0G-4bg2A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4bg2 PATF
(Prochloron
didemni) 		3 / 3 THR A 213
GLU A 290
ASN A 222
 None
 0.66A 6nj9K-4bg2A:
undetectable		 6nj9K-4bg2A:
21.00