SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bgd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 1k2rA-4bgdC:
undetectable
1k2rB-4bgdC:
undetectable		 1k2rA-4bgdC:
20.73
1k2rB-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 1k2sA-4bgdC:
undetectable
1k2sB-4bgdC:
undetectable		 1k2sA-4bgdC:
20.73
1k2sB-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 1k2sA-4bgdC:
undetectable
1k2sB-4bgdC:
undetectable		 1k2sA-4bgdC:
20.73
1k2sB-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 1k2tA-4bgdC:
undetectable
1k2tB-4bgdC:
undetectable		 1k2tA-4bgdC:
20.73
1k2tB-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.27A 1k2tA-4bgdC:
undetectable
1k2tB-4bgdC:
undetectable		 1k2tA-4bgdC:
20.73
1k2tB-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 1k2uA-4bgdC:
undetectable
1k2uB-4bgdC:
undetectable		 1k2uA-4bgdC:
20.73
1k2uB-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 1lzxA-4bgdC:
undetectable
1lzxB-4bgdC:
undetectable		 1lzxA-4bgdC:
20.73
1lzxB-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.27A 1lzzA-4bgdC:
undetectable
1lzzB-4bgdC:
undetectable		 1lzzA-4bgdC:
20.73
1lzzB-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.28A 1m00A-4bgdC:
undetectable
1m00B-4bgdC:
undetectable		 1m00A-4bgdC:
20.73
1m00B-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 1mmvA-4bgdC:
undetectable
1mmvB-4bgdC:
undetectable		 1mmvA-4bgdC:
20.73
1mmvB-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 1mmvA-4bgdC:
undetectable
1mmvB-4bgdC:
undetectable		 1mmvA-4bgdC:
20.73
1mmvB-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 1mmwA-4bgdC:
undetectable
1mmwB-4bgdC:
undetectable		 1mmwA-4bgdC:
20.73
1mmwB-4bgdC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 12 ILE C2207
PHE C2206
LEU C2226
THR C2276
LEU C2280
 None
 1.10A 1og5B-4bgdC:
undetectable		 1og5B-4bgdC:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 1om4A-4bgdC:
undetectable
1om4B-4bgdC:
undetectable		 1om4A-4bgdC:
20.99
1om4B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 1om4A-4bgdC:
undetectable
1om4B-4bgdC:
undetectable		 1om4A-4bgdC:
20.99
1om4B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 1om5A-4bgdC:
undetectable
1om5B-4bgdC:
undetectable		 1om5A-4bgdC:
20.63
1om5B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 1om5A-4bgdC:
undetectable
1om5B-4bgdC:
undetectable		 1om5A-4bgdC:
20.63
1om5B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 1p6hA-4bgdC:
undetectable
1p6hB-4bgdC:
undetectable		 1p6hA-4bgdC:
20.63
1p6hB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 1p6hA-4bgdC:
undetectable
1p6hB-4bgdC:
undetectable		 1p6hA-4bgdC:
20.63
1p6hB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 1p6iA-4bgdC:
undetectable
1p6iB-4bgdC:
undetectable		 1p6iA-4bgdC:
20.63
1p6iB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 1p6jA-4bgdC:
undetectable
1p6jB-4bgdC:
undetectable		 1p6jA-4bgdC:
20.63
1p6jB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 1p6jA-4bgdC:
undetectable
1p6jB-4bgdC:
undetectable		 1p6jA-4bgdC:
20.63
1p6jB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 1p6kA-4bgdC:
undetectable
1p6kB-4bgdC:
undetectable		 1p6kA-4bgdC:
20.63
1p6kB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TYR C2305
HIS C2260
PRO C2331
VAL C2274
 None
 1.37A 1q13A-4bgdC:
undetectable		 1q13A-4bgdC:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 1rs6A-4bgdC:
undetectable
1rs6B-4bgdC:
undetectable		 1rs6A-4bgdC:
20.63
1rs6B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 1zzqA-4bgdC:
undetectable
1zzqB-4bgdC:
undetectable		 1zzqA-4bgdC:
21.09
1zzqB-4bgdC:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 1zzqA-4bgdC:
undetectable
1zzqB-4bgdC:
undetectable		 1zzqA-4bgdC:
21.09
1zzqB-4bgdC:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.27A 1zzuA-4bgdC:
undetectable
1zzuB-4bgdC:
undetectable		 1zzuA-4bgdC:
21.09
1zzuB-4bgdC:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 2g6hA-4bgdC:
undetectable
2g6hB-4bgdC:
undetectable		 2g6hA-4bgdC:
21.09
2g6hB-4bgdC:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 2g6hA-4bgdC:
undetectable
2g6hB-4bgdC:
undetectable		 2g6hA-4bgdC:
21.09
2g6hB-4bgdC:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.27A 2g6kA-4bgdC:
undetectable
2g6kB-4bgdC:
undetectable		 2g6kA-4bgdC:
21.09
2g6kB-4bgdC:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 2g6kA-4bgdC:
undetectable
2g6kB-4bgdC:
undetectable		 2g6kA-4bgdC:
21.09
2g6kB-4bgdC:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.28A 2g6mA-4bgdC:
undetectable
2g6mB-4bgdC:
undetectable		 2g6mA-4bgdC:
21.09
2g6mB-4bgdC:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 2g6mA-4bgdC:
undetectable
2g6mB-4bgdC:
undetectable		 2g6mA-4bgdC:
21.09
2g6mB-4bgdC:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 2hx3A-4bgdC:
undetectable
2hx3B-4bgdC:
undetectable		 2hx3A-4bgdC:
20.99
2hx3B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 2hx3A-4bgdC:
undetectable
2hx3B-4bgdC:
undetectable		 2hx3A-4bgdC:
20.99
2hx3B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 2hx4A-4bgdC:
undetectable
2hx4B-4bgdC:
undetectable		 2hx4A-4bgdC:
20.99
2hx4B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 2hx4A-4bgdC:
undetectable
2hx4B-4bgdC:
undetectable		 2hx4A-4bgdC:
20.99
2hx4B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 GLY C2231
THR C2360
GLN C2229
PHE C2193
 None
 1.08A 2qx4A-4bgdC:
undetectable
2qx4B-4bgdC:
undetectable		 2qx4A-4bgdC:
22.64
2qx4B-4bgdC:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3b3mA-4bgdC:
undetectable
3b3mB-4bgdC:
undetectable		 3b3mA-4bgdC:
20.99
3b3mB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3b3nA-4bgdC:
undetectable
3b3nB-4bgdC:
undetectable		 3b3nA-4bgdC:
20.99
3b3nB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3b3nA-4bgdC:
undetectable
3b3nB-4bgdC:
undetectable		 3b3nA-4bgdC:
20.99
3b3nB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.28A 3b3oA-4bgdC:
undetectable
3b3oB-4bgdC:
undetectable		 3b3oA-4bgdC:
20.99
3b3oB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3b3oA-4bgdC:
undetectable
3b3oB-4bgdC:
undetectable		 3b3oA-4bgdC:
20.99
3b3oB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3b3pA-4bgdC:
undetectable
3b3pB-4bgdC:
undetectable		 3b3pA-4bgdC:
20.99
3b3pB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 3b3pA-4bgdC:
undetectable
3b3pB-4bgdC:
undetectable		 3b3pA-4bgdC:
20.99
3b3pB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.28A 3hsnA-4bgdC:
undetectable
3hsnB-4bgdC:
undetectable		 3hsnA-4bgdC:
20.99
3hsnB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 3hsnA-4bgdC:
undetectable
3hsnB-4bgdC:
undetectable		 3hsnA-4bgdC:
20.99
3hsnB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 3hsoA-4bgdC:
undetectable
3hsoB-4bgdC:
undetectable		 3hsoA-4bgdC:
20.99
3hsoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.28A 3hspA-4bgdC:
undetectable
3hspB-4bgdC:
undetectable		 3hspA-4bgdC:
20.99
3hspB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.26A 3hspA-4bgdC:
undetectable
3hspB-4bgdC:
undetectable		 3hspA-4bgdC:
20.99
3hspB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 3jt3A-4bgdC:
undetectable
3jt3B-4bgdC:
undetectable		 3jt3A-4bgdC:
20.99
3jt3B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 3jt3A-4bgdC:
undetectable
3jt3B-4bgdC:
undetectable		 3jt3A-4bgdC:
20.99
3jt3B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3jt4A-4bgdC:
undetectable
3jt4B-4bgdC:
undetectable		 3jt4A-4bgdC:
20.99
3jt4B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 3jt4A-4bgdC:
undetectable
3jt4B-4bgdC:
undetectable		 3jt4A-4bgdC:
20.99
3jt4B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3jt5A-4bgdC:
undetectable
3jt5B-4bgdC:
undetectable		 3jt5A-4bgdC:
20.99
3jt5B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 3jt6A-4bgdC:
undetectable
3jt6B-4bgdC:
undetectable		 3jt6A-4bgdC:
20.99
3jt6B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3jt7A-4bgdC:
undetectable
3jt7B-4bgdC:
undetectable		 3jt7A-4bgdC:
20.99
3jt7B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3jt7A-4bgdC:
undetectable
3jt7B-4bgdC:
undetectable		 3jt7A-4bgdC:
20.99
3jt7B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3jt8A-4bgdC:
undetectable
3jt8B-4bgdC:
undetectable		 3jt8A-4bgdC:
20.99
3jt8B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 3jt8A-4bgdC:
undetectable
3jt8B-4bgdC:
undetectable		 3jt8A-4bgdC:
20.99
3jt8B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 3jt9A-4bgdC:
undetectable
3jt9B-4bgdC:
undetectable		 3jt9A-4bgdC:
20.99
3jt9B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3jtaA-4bgdC:
undetectable
3jtaB-4bgdC:
undetectable		 3jtaA-4bgdC:
20.99
3jtaB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3jtaA-4bgdC:
undetectable
3jtaB-4bgdC:
undetectable		 3jtaA-4bgdC:
20.99
3jtaB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 3jwsA-4bgdC:
undetectable
3jwsB-4bgdC:
undetectable		 3jwsA-4bgdC:
20.99
3jwsB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3jwsA-4bgdC:
undetectable
3jwsB-4bgdC:
undetectable		 3jwsA-4bgdC:
20.99
3jwsB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3jwuA-4bgdC:
undetectable
3jwuB-4bgdC:
undetectable		 3jwuA-4bgdC:
20.99
3jwuB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 3jwvA-4bgdC:
undetectable
3jwvB-4bgdC:
undetectable		 3jwvA-4bgdC:
20.99
3jwvB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3jwvA-4bgdC:
undetectable
3jwvB-4bgdC:
undetectable		 3jwvA-4bgdC:
20.99
3jwvB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 3jx0A-4bgdC:
undetectable
3jx0B-4bgdC:
undetectable		 3jx0A-4bgdC:
20.99
3jx0B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.34A 3jx0A-4bgdC:
undetectable
3jx0B-4bgdC:
undetectable		 3jx0A-4bgdC:
20.99
3jx0B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 3jx1A-4bgdC:
undetectable
3jx1B-4bgdC:
undetectable		 3jx1A-4bgdC:
20.99
3jx1B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3jx5A-4bgdC:
undetectable
3jx5B-4bgdC:
undetectable		 3jx5A-4bgdC:
20.99
3jx5B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3n2rA-4bgdC:
undetectable
3n2rB-4bgdC:
undetectable		 3n2rA-4bgdC:
20.99
3n2rB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3n2rA-4bgdC:
undetectable
3n2rB-4bgdC:
undetectable		 3n2rA-4bgdC:
20.99
3n2rB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3n5vA-4bgdC:
undetectable
3n5vB-4bgdC:
undetectable		 3n5vA-4bgdC:
20.99
3n5vB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3n5vA-4bgdC:
undetectable
3n5vB-4bgdC:
undetectable		 3n5vA-4bgdC:
20.99
3n5vB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 3n5yA-4bgdC:
undetectable
3n5yB-4bgdC:
undetectable		 3n5yA-4bgdC:
20.99
3n5yB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3n5yA-4bgdC:
undetectable
3n5yB-4bgdC:
undetectable		 3n5yA-4bgdC:
20.99
3n5yB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3n5zA-4bgdC:
undetectable
3n5zB-4bgdC:
undetectable		 3n5zA-4bgdC:
20.99
3n5zB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3n61A-4bgdC:
undetectable
3n61B-4bgdC:
undetectable		 3n61A-4bgdC:
20.99
3n61B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.28A 3n65A-4bgdC:
undetectable
3n65B-4bgdC:
undetectable		 3n65A-4bgdC:
20.99
3n65B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3nlkA-4bgdC:
undetectable
3nlkB-4bgdC:
undetectable		 3nlkA-4bgdC:
20.99
3nlkB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 3nlkA-4bgdC:
undetectable
3nlkB-4bgdC:
undetectable		 3nlkA-4bgdC:
20.99
3nlkB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3nlmA-4bgdC:
undetectable
3nlmB-4bgdC:
undetectable		 3nlmA-4bgdC:
20.99
3nlmB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3nlmA-4bgdC:
undetectable
3nlmB-4bgdC:
undetectable		 3nlmA-4bgdC:
20.99
3nlmB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 3nlnA-4bgdC:
undetectable
3nlnB-4bgdC:
undetectable		 3nlnA-4bgdC:
20.99
3nlnB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 3nloA-4bgdC:
undetectable
3nloB-4bgdC:
undetectable		 3nloA-4bgdC:
20.99
3nloB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 3nloA-4bgdC:
undetectable
3nloB-4bgdC:
undetectable		 3nloA-4bgdC:
20.99
3nloB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 3nlqA-4bgdC:
undetectable
3nlqB-4bgdC:
undetectable		 3nlqA-4bgdC:
20.99
3nlqB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.28A 3nlvA-4bgdC:
undetectable
3nlvB-4bgdC:
undetectable		 3nlvA-4bgdC:
20.99
3nlvB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3nlvA-4bgdC:
undetectable
3nlvB-4bgdC:
undetectable		 3nlvA-4bgdC:
20.99
3nlvB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.28A 3nlwA-4bgdC:
undetectable
3nlwB-4bgdC:
undetectable		 3nlwA-4bgdC:
20.99
3nlwB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3nlwA-4bgdC:
undetectable
3nlwB-4bgdC:
undetectable		 3nlwA-4bgdC:
20.99
3nlwB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 3nlxA-4bgdC:
undetectable
3nlxB-4bgdC:
undetectable		 3nlxA-4bgdC:
20.99
3nlxB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3nlxA-4bgdC:
undetectable
3nlxB-4bgdC:
undetectable		 3nlxA-4bgdC:
20.99
3nlxB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 3nlyA-4bgdC:
undetectable
3nlyB-4bgdC:
undetectable		 3nlyA-4bgdC:
20.99
3nlyB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3nm0A-4bgdC:
undetectable
3nm0B-4bgdC:
undetectable		 3nm0A-4bgdC:
20.99
3nm0B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 3nm0A-4bgdC:
undetectable
3nm0B-4bgdC:
undetectable		 3nm0A-4bgdC:
20.99
3nm0B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3nnyA-4bgdC:
undetectable
3nnyB-4bgdC:
undetectable		 3nnyA-4bgdC:
20.99
3nnyB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.27A 3nnzA-4bgdC:
undetectable
3nnzB-4bgdC:
undetectable		 3nnzA-4bgdC:
20.99
3nnzB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3pnfA-4bgdC:
undetectable
3pnfB-4bgdC:
undetectable		 3pnfA-4bgdC:
20.99
3pnfB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3pnfA-4bgdC:
undetectable
3pnfB-4bgdC:
undetectable		 3pnfA-4bgdC:
20.99
3pnfB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3pngA-4bgdC:
undetectable
3pngB-4bgdC:
undetectable		 3pngA-4bgdC:
20.99
3pngB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.33A 3pngA-4bgdC:
undetectable
3pngB-4bgdC:
undetectable		 3pngA-4bgdC:
20.99
3pngB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3q99A-4bgdC:
undetectable
3q99B-4bgdC:
undetectable		 3q99A-4bgdC:
20.99
3q99B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 3q9aA-4bgdC:
undetectable
3q9aB-4bgdC:
undetectable		 3q9aA-4bgdC:
20.99
3q9aB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 3rqjA-4bgdC:
undetectable
3rqjB-4bgdC:
undetectable		 3rqjA-4bgdC:
20.99
3rqjB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3rqjA-4bgdC:
undetectable
3rqjB-4bgdC:
undetectable		 3rqjA-4bgdC:
20.99
3rqjB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3rqkA-4bgdC:
undetectable
3rqkB-4bgdC:
undetectable		 3rqkA-4bgdC:
20.99
3rqkB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 3rqlA-4bgdC:
undetectable
3rqlB-4bgdC:
undetectable		 3rqlA-4bgdC:
20.99
3rqlB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3rqlA-4bgdC:
undetectable
3rqlB-4bgdC:
undetectable		 3rqlA-4bgdC:
20.99
3rqlB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3rqmA-4bgdC:
undetectable
3rqmB-4bgdC:
undetectable		 3rqmA-4bgdC:
20.99
3rqmB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3rqmA-4bgdC:
undetectable
3rqmB-4bgdC:
undetectable		 3rqmA-4bgdC:
20.99
3rqmB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3rqnA-4bgdC:
undetectable
3rqnB-4bgdC:
undetectable		 3rqnA-4bgdC:
20.99
3rqnB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 3rqnA-4bgdC:
undetectable
3rqnB-4bgdC:
undetectable		 3rqnA-4bgdC:
20.99
3rqnB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3svpA-4bgdC:
undetectable
3svpB-4bgdC:
undetectable		 3svpA-4bgdC:
20.99
3svpB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3svpA-4bgdC:
undetectable
3svpB-4bgdC:
undetectable		 3svpA-4bgdC:
20.99
3svpB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 3svqA-4bgdC:
undetectable
3svqB-4bgdC:
undetectable		 3svqA-4bgdC:
20.99
3svqB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3svqA-4bgdC:
undetectable
3svqB-4bgdC:
undetectable		 3svqA-4bgdC:
20.99
3svqB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 PHE C2329
ASN C2318
ALA C2275
LEU C2307
 None
 0.95A 3t3sC-4bgdC:
undetectable		 3t3sC-4bgdC:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 3tylA-4bgdC:
undetectable
3tylB-4bgdC:
undetectable		 3tylA-4bgdC:
20.99
3tylB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3tylA-4bgdC:
undetectable
3tylB-4bgdC:
undetectable		 3tylA-4bgdC:
20.99
3tylB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 3tymA-4bgdC:
undetectable
3tymB-4bgdC:
undetectable		 3tymA-4bgdC:
20.99
3tymB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 3tymA-4bgdC:
undetectable
3tymB-4bgdC:
undetectable		 3tymA-4bgdC:
20.99
3tymB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 3tynA-4bgdC:
undetectable
3tynB-4bgdC:
undetectable		 3tynA-4bgdC:
20.99
3tynB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 3tyoA-4bgdC:
undetectable
3tyoB-4bgdC:
undetectable		 3tyoA-4bgdC:
20.99
3tyoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.33A 3tyoA-4bgdC:
undetectable
3tyoB-4bgdC:
undetectable		 3tyoA-4bgdC:
20.99
3tyoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.27A 3ufoA-4bgdC:
undetectable
3ufoB-4bgdC:
undetectable		 3ufoA-4bgdC:
20.99
3ufoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3ufoA-4bgdC:
undetectable
3ufoB-4bgdC:
undetectable		 3ufoA-4bgdC:
20.99
3ufoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3ufpA-4bgdC:
undetectable
3ufpB-4bgdC:
undetectable		 3ufpA-4bgdC:
20.99
3ufpB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 3ufpA-4bgdC:
undetectable
3ufpB-4bgdC:
undetectable		 3ufpA-4bgdC:
20.99
3ufpB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 3ufqA-4bgdC:
undetectable
3ufqB-4bgdC:
undetectable		 3ufqA-4bgdC:
20.99
3ufqB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 3ufrA-4bgdC:
undetectable
3ufrB-4bgdC:
undetectable		 3ufrA-4bgdC:
20.99
3ufrB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.27A 3ufrA-4bgdC:
undetectable
3ufrB-4bgdC:
undetectable		 3ufrA-4bgdC:
20.99
3ufrB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.28A 3ufsA-4bgdC:
undetectable
3ufsB-4bgdC:
undetectable		 3ufsA-4bgdC:
20.99
3ufsB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 3ufuA-4bgdC:
undetectable
3ufuB-4bgdC:
undetectable		 3ufuA-4bgdC:
20.99
3ufuB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 3ufuA-4bgdC:
undetectable
3ufuB-4bgdC:
undetectable		 3ufuA-4bgdC:
20.99
3ufuB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 3ufvA-4bgdC:
undetectable
3ufvB-4bgdC:
undetectable		 3ufvA-4bgdC:
20.99
3ufvB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 3ufvA-4bgdC:
undetectable
3ufvB-4bgdC:
undetectable		 3ufvA-4bgdC:
20.99
3ufvB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 3ufwA-4bgdC:
undetectable
3ufwB-4bgdC:
undetectable		 3ufwA-4bgdC:
20.99
3ufwB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 10 GLN C2229
HIS C2260
PHE C2206
LEU C2280
THR C2276
 None
 1.44A 3zncA-4bgdC:
undetectable		 3zncA-4bgdC:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 4c39A-4bgdC:
undetectable
4c39B-4bgdC:
undetectable		 4c39A-4bgdC:
20.99
4c39B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4camA-4bgdC:
undetectable
4camB-4bgdC:
undetectable		 4camA-4bgdC:
20.99
4camB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 4camA-4bgdC:
undetectable
4camB-4bgdC:
undetectable		 4camA-4bgdC:
20.99
4camB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 4canA-4bgdC:
undetectable
4canB-4bgdC:
undetectable		 4canA-4bgdC:
20.99
4canB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 4caoA-4bgdC:
undetectable
4caoB-4bgdC:
undetectable		 4caoA-4bgdC:
20.99
4caoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 4caoA-4bgdC:
undetectable
4caoB-4bgdC:
undetectable		 4caoA-4bgdC:
20.99
4caoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4capA-4bgdC:
undetectable
4capB-4bgdC:
undetectable		 4capA-4bgdC:
20.99
4capB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4caqA-4bgdC:
undetectable
4caqB-4bgdC:
undetectable		 4caqA-4bgdC:
20.99
4caqB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 4caqA-4bgdC:
undetectable
4caqB-4bgdC:
undetectable		 4caqA-4bgdC:
20.99
4caqB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 4cdtA-4bgdC:
undetectable
4cdtB-4bgdC:
undetectable		 4cdtA-4bgdC:
20.99
4cdtB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 4cdtA-4bgdC:
undetectable
4cdtB-4bgdC:
undetectable		 4cdtA-4bgdC:
20.99
4cdtB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4ctpA-4bgdC:
undetectable
4ctpB-4bgdC:
undetectable		 4ctpA-4bgdC:
20.99
4ctpB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 4ctqA-4bgdC:
undetectable
4ctqB-4bgdC:
undetectable		 4ctqA-4bgdC:
20.99
4ctqB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.36A 4ctrA-4bgdC:
undetectable
4ctrB-4bgdC:
undetectable		 4ctrA-4bgdC:
20.99
4ctrB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.34A 4ctrA-4bgdC:
undetectable
4ctrB-4bgdC:
undetectable		 4ctrA-4bgdC:
20.99
4ctrB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4ctuA-4bgdC:
undetectable
4ctuB-4bgdC:
undetectable		 4ctuA-4bgdC:
20.99
4ctuB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 4ctvA-4bgdC:
undetectable
4ctvB-4bgdC:
undetectable		 4ctvA-4bgdC:
20.99
4ctvB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 4ctvA-4bgdC:
undetectable
4ctvB-4bgdC:
undetectable		 4ctvA-4bgdC:
20.99
4ctvB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4ctwA-4bgdC:
undetectable
4ctwB-4bgdC:
undetectable		 4ctwA-4bgdC:
20.99
4ctwB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 4ctwA-4bgdC:
undetectable
4ctwB-4bgdC:
undetectable		 4ctwA-4bgdC:
20.99
4ctwB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4ctxA-4bgdC:
undetectable
4ctxB-4bgdC:
undetectable		 4ctxA-4bgdC:
20.99
4ctxB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 4ctxA-4bgdC:
undetectable
4ctxB-4bgdC:
undetectable		 4ctxA-4bgdC:
20.99
4ctxB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 4cx5A-4bgdC:
undetectable
4cx5B-4bgdC:
undetectable		 4cx5A-4bgdC:
20.99
4cx5B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 4cx5A-4bgdC:
undetectable
4cx5B-4bgdC:
undetectable		 4cx5A-4bgdC:
20.99
4cx5B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 4cx6A-4bgdC:
undetectable
4cx6B-4bgdC:
undetectable		 4cx6A-4bgdC:
20.99
4cx6B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 4cx6A-4bgdC:
undetectable
4cx6B-4bgdC:
undetectable		 4cx6A-4bgdC:
20.99
4cx6B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.27A 4d1nA-4bgdC:
undetectable
4d1nB-4bgdC:
undetectable		 4d1nA-4bgdC:
20.63
4d1nB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 4d1nA-4bgdC:
undetectable
4d1nB-4bgdC:
undetectable		 4d1nA-4bgdC:
20.63
4d1nB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4d1nC-4bgdC:
undetectable
4d1nD-4bgdC:
undetectable		 4d1nC-4bgdC:
20.63
4d1nD-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 4d1nC-4bgdC:
undetectable
4d1nD-4bgdC:
undetectable		 4d1nC-4bgdC:
20.63
4d1nD-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4d2yA-4bgdC:
undetectable
4d2yB-4bgdC:
undetectable		 4d2yA-4bgdC:
20.99
4d2yB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4d2zA-4bgdC:
undetectable
4d2zB-4bgdC:
undetectable		 4d2zA-4bgdC:
20.99
4d2zB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 4d2zA-4bgdC:
undetectable
4d2zB-4bgdC:
undetectable		 4d2zA-4bgdC:
20.99
4d2zB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 4d30A-4bgdC:
undetectable
4d30B-4bgdC:
undetectable		 4d30A-4bgdC:
20.99
4d30B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 4d31A-4bgdC:
undetectable
4d31B-4bgdC:
undetectable		 4d31A-4bgdC:
20.99
4d31B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4d3bA-4bgdC:
undetectable
4d3bB-4bgdC:
undetectable		 4d3bA-4bgdC:
20.99
4d3bB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 PHE C2329
ASN C2318
ALA C2275
LEU C2307
 None
 0.99A 4ejgD-4bgdC:
undetectable		 4ejgD-4bgdC:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4euxA-4bgdC:
undetectable
4euxB-4bgdC:
undetectable		 4euxA-4bgdC:
20.99
4euxB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4fvwA-4bgdC:
undetectable
4fvwB-4bgdC:
undetectable		 4fvwA-4bgdC:
20.99
4fvwB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 4fvwA-4bgdC:
undetectable
4fvwB-4bgdC:
undetectable		 4fvwA-4bgdC:
20.99
4fvwB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4fvxA-4bgdC:
undetectable
4fvxB-4bgdC:
undetectable		 4fvxA-4bgdC:
20.99
4fvxB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 4fvxA-4bgdC:
undetectable
4fvxB-4bgdC:
undetectable		 4fvxA-4bgdC:
20.99
4fvxB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4fvyA-4bgdC:
undetectable
4fvyB-4bgdC:
undetectable		 4fvyA-4bgdC:
20.99
4fvyB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 4fvyA-4bgdC:
undetectable
4fvyB-4bgdC:
undetectable		 4fvyA-4bgdC:
20.99
4fvyB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4fw0A-4bgdC:
undetectable
4fw0B-4bgdC:
undetectable		 4fw0A-4bgdC:
20.99
4fw0B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4gqeA-4bgdC:
undetectable
4gqeB-4bgdC:
undetectable		 4gqeA-4bgdC:
20.99
4gqeB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 4gqeA-4bgdC:
undetectable
4gqeB-4bgdC:
undetectable		 4gqeA-4bgdC:
20.99
4gqeB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 ILE C2259
VAL C2184
PHE C2349
ASP C2343
 None
 1.14A 4iarA-4bgdC:
undetectable		 4iarA-4bgdC:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4imtA-4bgdC:
undetectable
4imtB-4bgdC:
undetectable		 4imtA-4bgdC:
20.99
4imtB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 4imtA-4bgdC:
undetectable
4imtB-4bgdC:
undetectable		 4imtA-4bgdC:
20.99
4imtB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA809_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 4imuA-4bgdC:
undetectable
4imuB-4bgdC:
undetectable		 4imuA-4bgdC:
20.99
4imuB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4imwA-4bgdC:
undetectable
4imwB-4bgdC:
undetectable		 4imwA-4bgdC:
20.99
4imwB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.36A 4jseA-4bgdC:
undetectable
4jseB-4bgdC:
undetectable		 4jseA-4bgdC:
20.99
4jseB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.36A 4jseA-4bgdC:
undetectable
4jseB-4bgdC:
undetectable		 4jseA-4bgdC:
20.99
4jseB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 4jsfA-4bgdC:
undetectable
4jsfB-4bgdC:
undetectable		 4jsfA-4bgdC:
20.99
4jsfB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 4jsfA-4bgdC:
undetectable
4jsfB-4bgdC:
undetectable		 4jsfA-4bgdC:
20.99
4jsfB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 4jsgA-4bgdC:
undetectable
4jsgB-4bgdC:
undetectable		 4jsgA-4bgdC:
20.99
4jsgB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.33A 4jsgA-4bgdC:
undetectable
4jsgB-4bgdC:
undetectable		 4jsgA-4bgdC:
20.99
4jsgB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.33A 4jshA-4bgdC:
undetectable
4jshB-4bgdC:
undetectable		 4jshA-4bgdC:
20.99
4jshB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 4jsiA-4bgdC:
undetectable
4jsiB-4bgdC:
undetectable		 4jsiA-4bgdC:
20.99
4jsiB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 4jsjA-4bgdC:
undetectable
4jsjB-4bgdC:
undetectable		 4jsjA-4bgdC:
20.99
4jsjB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 4jsjA-4bgdC:
undetectable
4jsjB-4bgdC:
undetectable		 4jsjA-4bgdC:
20.99
4jsjB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.28A 4k5dA-4bgdC:
undetectable
4k5dB-4bgdC:
undetectable		 4k5dA-4bgdC:
20.99
4k5dB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 4k5dA-4bgdC:
undetectable
4k5dB-4bgdC:
undetectable		 4k5dA-4bgdC:
20.99
4k5dB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 4k5eA-4bgdC:
undetectable
4k5eB-4bgdC:
undetectable		 4k5eA-4bgdC:
20.99
4k5eB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 4k5eA-4bgdC:
undetectable
4k5eB-4bgdC:
undetectable		 4k5eA-4bgdC:
20.99
4k5eB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.34A 4k5fA-4bgdC:
undetectable
4k5fB-4bgdC:
undetectable		 4k5fA-4bgdC:
20.99
4k5fB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4k5gA-4bgdC:
undetectable
4k5gB-4bgdC:
undetectable		 4k5gA-4bgdC:
20.99
4k5gB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 4k5gA-4bgdC:
undetectable
4k5gB-4bgdC:
undetectable		 4k5gA-4bgdC:
20.99
4k5gB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4kchA-4bgdC:
undetectable
4kchB-4bgdC:
undetectable		 4kchA-4bgdC:
20.99
4kchB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 4kciA-4bgdC:
undetectable
4kciB-4bgdC:
undetectable		 4kciA-4bgdC:
20.99
4kciB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.27A 4kciA-4bgdC:
undetectable
4kciB-4bgdC:
undetectable		 4kciA-4bgdC:
20.99
4kciB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4kcjA-4bgdC:
undetectable
4kcjB-4bgdC:
undetectable		 4kcjA-4bgdC:
20.99
4kcjB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 4kcjA-4bgdC:
undetectable
4kcjB-4bgdC:
undetectable		 4kcjA-4bgdC:
20.99
4kcjB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 4kclA-4bgdC:
undetectable
4kclB-4bgdC:
undetectable		 4kclA-4bgdC:
20.99
4kclB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 4kclA-4bgdC:
undetectable
4kclB-4bgdC:
undetectable		 4kclA-4bgdC:
20.99
4kclB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.28A 4kcnA-4bgdC:
undetectable
4kcnB-4bgdC:
undetectable		 4kcnA-4bgdC:
20.99
4kcnB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 4kcnA-4bgdC:
undetectable
4kcnB-4bgdC:
undetectable		 4kcnA-4bgdC:
20.99
4kcnB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4kcoA-4bgdC:
undetectable
4kcoB-4bgdC:
undetectable		 4kcoA-4bgdC:
20.99
4kcoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 4kcoA-4bgdC:
undetectable
4kcoB-4bgdC:
undetectable		 4kcoA-4bgdC:
20.99
4kcoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4luxA-4bgdC:
undetectable
4luxB-4bgdC:
undetectable		 4luxA-4bgdC:
20.99
4luxB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 4luxA-4bgdC:
undetectable
4luxB-4bgdC:
undetectable		 4luxA-4bgdC:
20.99
4luxB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4uchA-4bgdC:
undetectable
4uchB-4bgdC:
undetectable		 4uchA-4bgdC:
20.99
4uchB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 4uchA-4bgdC:
undetectable
4uchB-4bgdC:
undetectable		 4uchA-4bgdC:
20.99
4uchB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 4ugzA-4bgdC:
undetectable
4ugzB-4bgdC:
undetectable		 4ugzA-4bgdC:
20.99
4ugzB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 4uh0A-4bgdC:
undetectable
4uh0B-4bgdC:
undetectable		 4uh0A-4bgdC:
20.99
4uh0B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 4uh0A-4bgdC:
undetectable
4uh0B-4bgdC:
undetectable		 4uh0A-4bgdC:
20.99
4uh0B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4uh1A-4bgdC:
undetectable
4uh1B-4bgdC:
undetectable		 4uh1A-4bgdC:
20.99
4uh1B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 4uh1A-4bgdC:
undetectable
4uh1B-4bgdC:
undetectable		 4uh1A-4bgdC:
20.99
4uh1B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.34A 4uh2A-4bgdC:
undetectable
4uh2B-4bgdC:
undetectable		 4uh2A-4bgdC:
20.99
4uh2B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 4uh2A-4bgdC:
undetectable
4uh2B-4bgdC:
undetectable		 4uh2A-4bgdC:
20.99
4uh2B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.34A 4uh3A-4bgdC:
undetectable
4uh3B-4bgdC:
undetectable		 4uh3A-4bgdC:
20.99
4uh3B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 4uh3A-4bgdC:
undetectable
4uh3B-4bgdC:
undetectable		 4uh3A-4bgdC:
20.99
4uh3B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 4uh4A-4bgdC:
undetectable
4uh4B-4bgdC:
undetectable		 4uh4A-4bgdC:
20.99
4uh4B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4uh5A-4bgdC:
undetectable
4uh5B-4bgdC:
undetectable		 4uh5A-4bgdC:
20.63
4uh5B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 4uh5A-4bgdC:
undetectable
4uh5B-4bgdC:
undetectable		 4uh5A-4bgdC:
20.63
4uh5B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.34A 4uh6A-4bgdC:
undetectable
4uh6B-4bgdC:
undetectable		 4uh6A-4bgdC:
20.63
4uh6B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 4uh6A-4bgdC:
undetectable
4uh6B-4bgdC:
undetectable		 4uh6A-4bgdC:
20.63
4uh6B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4upmA-4bgdC:
undetectable
4upmB-4bgdC:
undetectable		 4upmA-4bgdC:
20.99
4upmB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 4upmA-4bgdC:
undetectable
4upmB-4bgdC:
undetectable		 4upmA-4bgdC:
20.99
4upmB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 4upoA-4bgdC:
undetectable
4upoB-4bgdC:
undetectable		 4upoA-4bgdC:
20.99
4upoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 4uppA-4bgdC:
undetectable
4uppB-4bgdC:
undetectable		 4uppA-4bgdC:
20.99
4uppB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4v3uA-4bgdC:
undetectable
4v3uB-4bgdC:
undetectable		 4v3uA-4bgdC:
20.63
4v3uB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 4v3vA-4bgdC:
undetectable
4v3vB-4bgdC:
undetectable		 4v3vA-4bgdC:
20.99
4v3vB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 4v3xA-4bgdC:
undetectable
4v3xB-4bgdC:
undetectable		 4v3xA-4bgdC:
20.99
4v3xB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 4v3yA-4bgdC:
undetectable
4v3yB-4bgdC:
undetectable		 4v3yA-4bgdC:
20.99
4v3yB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.35A 5ad4A-4bgdC:
undetectable
5ad4B-4bgdC:
undetectable		 5ad4A-4bgdC:
20.99
5ad4B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5ad4A-4bgdC:
undetectable
5ad4B-4bgdC:
undetectable		 5ad4A-4bgdC:
20.99
5ad4B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.34A 5ad5A-4bgdC:
undetectable
5ad5B-4bgdC:
undetectable		 5ad5A-4bgdC:
20.99
5ad5B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 5ad5A-4bgdC:
undetectable
5ad5B-4bgdC:
undetectable		 5ad5A-4bgdC:
20.99
5ad5B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.35A 5ad6A-4bgdC:
undetectable
5ad6B-4bgdC:
undetectable		 5ad6A-4bgdC:
20.99
5ad6B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5ad6A-4bgdC:
undetectable
5ad6B-4bgdC:
undetectable		 5ad6A-4bgdC:
20.99
5ad6B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5ad7A-4bgdC:
undetectable
5ad7B-4bgdC:
undetectable		 5ad7A-4bgdC:
20.99
5ad7B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.34A 5ad8A-4bgdC:
undetectable
5ad8B-4bgdC:
undetectable		 5ad8A-4bgdC:
20.99
5ad8B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.34A 5ad9A-4bgdC:
undetectable
5ad9B-4bgdC:
undetectable		 5ad9A-4bgdC:
20.99
5ad9B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5ad9A-4bgdC:
undetectable
5ad9B-4bgdC:
undetectable		 5ad9A-4bgdC:
20.99
5ad9B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 5adaA-4bgdC:
undetectable
5adaB-4bgdC:
undetectable		 5adaA-4bgdC:
20.99
5adaB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.33A 5adaA-4bgdC:
undetectable
5adaB-4bgdC:
undetectable		 5adaA-4bgdC:
20.99
5adaB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.36A 5adbA-4bgdC:
undetectable
5adbB-4bgdC:
undetectable		 5adbA-4bgdC:
20.99
5adbB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 5adcA-4bgdC:
undetectable
5adcB-4bgdC:
undetectable		 5adcA-4bgdC:
20.99
5adcB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.33A 5adeA-4bgdC:
undetectable
5adeB-4bgdC:
undetectable		 5adeA-4bgdC:
20.99
5adeB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 5adfA-4bgdC:
undetectable
5adfB-4bgdC:
undetectable		 5adfA-4bgdC:
20.63
5adfB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 5adgA-4bgdC:
undetectable
5adgB-4bgdC:
undetectable		 5adgA-4bgdC:
20.63
5adgB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5adgA-4bgdC:
undetectable
5adgB-4bgdC:
undetectable		 5adgA-4bgdC:
20.63
5adgB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 5adiA-4bgdC:
undetectable
5adiB-4bgdC:
undetectable		 5adiA-4bgdC:
20.63
5adiB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 5agkA-4bgdC:
undetectable
5agkB-4bgdC:
undetectable		 5agkA-4bgdC:
20.99
5agkB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 5aglA-4bgdC:
undetectable
5aglB-4bgdC:
undetectable		 5aglA-4bgdC:
20.99
5aglB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 5aglA-4bgdC:
undetectable
5aglB-4bgdC:
undetectable		 5aglA-4bgdC:
20.99
5aglB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 5agmA-4bgdC:
undetectable
5agmB-4bgdC:
undetectable		 5agmA-4bgdC:
20.99
5agmB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 5agmA-4bgdC:
undetectable
5agmB-4bgdC:
undetectable		 5agmA-4bgdC:
20.99
5agmB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 5agoA-4bgdC:
undetectable
5agoB-4bgdC:
undetectable		 5agoA-4bgdC:
20.99
5agoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5agoA-4bgdC:
undetectable
5agoB-4bgdC:
undetectable		 5agoA-4bgdC:
20.99
5agoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.35A 5agpA-4bgdC:
undetectable
5agpB-4bgdC:
undetectable		 5agpA-4bgdC:
20.99
5agpB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5agpA-4bgdC:
undetectable
5agpB-4bgdC:
undetectable		 5agpA-4bgdC:
20.99
5agpB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		3 / 3 TYR C2208
THR C2250
THR C2223
 None
 0.81A 5aoxE-4bgdC:
undetectable		 5aoxE-4bgdC:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 5fvpA-4bgdC:
undetectable
5fvpB-4bgdC:
undetectable		 5fvpA-4bgdC:
20.99
5fvpB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.36A 5fvpA-4bgdC:
undetectable
5fvpB-4bgdC:
undetectable		 5fvpA-4bgdC:
20.99
5fvpB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 5fvqA-4bgdC:
undetectable
5fvqB-4bgdC:
undetectable		 5fvqA-4bgdC:
20.99
5fvqB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 5fvrA-4bgdC:
undetectable
5fvrB-4bgdC:
undetectable		 5fvrA-4bgdC:
20.99
5fvrB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5fvrA-4bgdC:
undetectable
5fvrB-4bgdC:
undetectable		 5fvrA-4bgdC:
20.99
5fvrB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 5fvsA-4bgdC:
undetectable
5fvsB-4bgdC:
undetectable		 5fvsA-4bgdC:
20.99
5fvsB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 5fvtA-4bgdC:
undetectable
5fvtB-4bgdC:
undetectable		 5fvtA-4bgdC:
20.99
5fvtB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5fvtA-4bgdC:
undetectable
5fvtB-4bgdC:
undetectable		 5fvtA-4bgdC:
20.99
5fvtB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.26A 5fvuA-4bgdC:
undetectable
5fvuB-4bgdC:
undetectable		 5fvuA-4bgdC:
20.63
5fvuB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.27A 5fvvA-4bgdC:
undetectable
5fvvB-4bgdC:
undetectable		 5fvvA-4bgdC:
20.63
5fvvB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5fvwA-4bgdC:
undetectable
5fvwB-4bgdC:
undetectable		 5fvwA-4bgdC:
20.63
5fvwB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 5fw0A-4bgdC:
undetectable
5fw0B-4bgdC:
undetectable		 5fw0A-4bgdC:
20.99
5fw0B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5fw0A-4bgdC:
undetectable
5fw0B-4bgdC:
undetectable		 5fw0A-4bgdC:
20.99
5fw0B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 5g0nA-4bgdC:
undetectable
5g0nB-4bgdC:
undetectable		 5g0nA-4bgdC:
20.99
5g0nB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5g0nA-4bgdC:
undetectable
5g0nB-4bgdC:
undetectable		 5g0nA-4bgdC:
20.99
5g0nB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 5g0oA-4bgdC:
undetectable
5g0oB-4bgdC:
undetectable		 5g0oA-4bgdC:
20.99
5g0oB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5g0oA-4bgdC:
undetectable
5g0oB-4bgdC:
undetectable		 5g0oA-4bgdC:
20.99
5g0oB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 5g0pA-4bgdC:
undetectable
5g0pB-4bgdC:
undetectable		 5g0pA-4bgdC:
20.99
5g0pB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5unrA-4bgdC:
undetectable
5unrB-4bgdC:
undetectable		 5unrA-4bgdC:
20.99
5unrB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.34A 5unsA-4bgdC:
undetectable
5unsB-4bgdC:
undetectable		 5unsA-4bgdC:
20.99
5unsB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5unsA-4bgdC:
undetectable
5unsB-4bgdC:
undetectable		 5unsA-4bgdC:
20.99
5unsB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.35A 5untA-4bgdC:
undetectable
5untB-4bgdC:
undetectable		 5untA-4bgdC:
20.99
5untB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.37A 5unuA-4bgdC:
undetectable
5unuB-4bgdC:
undetectable		 5unuA-4bgdC:
20.99
5unuB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.36A 5unuA-4bgdC:
undetectable
5unuB-4bgdC:
undetectable		 5unuA-4bgdC:
20.99
5unuB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.35A 5unvA-4bgdC:
undetectable
5unvB-4bgdC:
undetectable		 5unvA-4bgdC:
20.99
5unvB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.34A 5unvA-4bgdC:
undetectable
5unvB-4bgdC:
undetectable		 5unvA-4bgdC:
20.99
5unvB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.37A 5unwA-4bgdC:
undetectable
5unwB-4bgdC:
undetectable		 5unwA-4bgdC:
20.99
5unwB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.36A 5unxA-4bgdC:
undetectable
5unxB-4bgdC:
undetectable		 5unxA-4bgdC:
20.99
5unxB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.37A 5unyA-4bgdC:
undetectable
5unyB-4bgdC:
undetectable		 5unyA-4bgdC:
20.99
5unyB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.35A 5unyA-4bgdC:
undetectable
5unyB-4bgdC:
undetectable		 5unyA-4bgdC:
20.99
5unyB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.34A 5unzA-4bgdC:
undetectable
5unzB-4bgdC:
undetectable		 5unzA-4bgdC:
20.99
5unzB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.34A 5uo0A-4bgdC:
undetectable
5uo0B-4bgdC:
undetectable		 5uo0A-4bgdC:
20.99
5uo0B-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 5uo1A-4bgdC:
undetectable
5uo1B-4bgdC:
undetectable		 5uo1A-4bgdC:
20.63
5uo1B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 5uo1A-4bgdC:
undetectable
5uo1B-4bgdC:
undetectable		 5uo1A-4bgdC:
20.63
5uo1B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 5uo2A-4bgdC:
undetectable
5uo2B-4bgdC:
undetectable		 5uo2A-4bgdC:
20.63
5uo2B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 5uo2A-4bgdC:
undetectable
5uo2B-4bgdC:
undetectable		 5uo2A-4bgdC:
20.63
5uo2B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 5uo3A-4bgdC:
undetectable
5uo3B-4bgdC:
undetectable		 5uo3A-4bgdC:
20.63
5uo3B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.34A 5uo3A-4bgdC:
undetectable
5uo3B-4bgdC:
undetectable		 5uo3A-4bgdC:
20.63
5uo3B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 5uo4A-4bgdC:
undetectable
5uo4B-4bgdC:
undetectable		 5uo4A-4bgdC:
20.63
5uo4B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.27A 5uo4A-4bgdC:
undetectable
5uo4B-4bgdC:
undetectable		 5uo4A-4bgdC:
20.63
5uo4B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 5uo5A-4bgdC:
undetectable
5uo5B-4bgdC:
undetectable		 5uo5A-4bgdC:
20.63
5uo5B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 5uo5A-4bgdC:
undetectable
5uo5B-4bgdC:
undetectable		 5uo5A-4bgdC:
20.63
5uo5B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5uo6A-4bgdC:
undetectable
5uo6B-4bgdC:
undetectable		 5uo6A-4bgdC:
20.63
5uo6B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 5uo7A-4bgdC:
undetectable
5uo7B-4bgdC:
undetectable		 5uo7A-4bgdC:
20.63
5uo7B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5uo7A-4bgdC:
undetectable
5uo7B-4bgdC:
undetectable		 5uo7A-4bgdC:
20.63
5uo7B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 5vujA-4bgdC:
undetectable
5vujB-4bgdC:
undetectable		 5vujA-4bgdC:
20.99
5vujB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.34A 5vujA-4bgdC:
undetectable
5vujB-4bgdC:
undetectable		 5vujA-4bgdC:
20.99
5vujB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.34A 5vukA-4bgdC:
undetectable
5vukB-4bgdC:
undetectable		 5vukA-4bgdC:
20.99
5vukB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5vukA-4bgdC:
undetectable
5vukB-4bgdC:
undetectable		 5vukA-4bgdC:
20.99
5vukB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 5vulA-4bgdC:
undetectable
5vulB-4bgdC:
undetectable		 5vulA-4bgdC:
20.99
5vulB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5vulA-4bgdC:
undetectable
5vulB-4bgdC:
undetectable		 5vulA-4bgdC:
20.99
5vulB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 5vumA-4bgdC:
undetectable
5vumB-4bgdC:
undetectable		 5vumA-4bgdC:
20.99
5vumB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5vumA-4bgdC:
undetectable
5vumB-4bgdC:
undetectable		 5vumA-4bgdC:
20.99
5vumB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 5vunA-4bgdC:
undetectable
5vunB-4bgdC:
undetectable		 5vunA-4bgdC:
20.99
5vunB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5vunA-4bgdC:
undetectable
5vunB-4bgdC:
undetectable		 5vunA-4bgdC:
20.99
5vunB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 5vuoA-4bgdC:
undetectable
5vuoB-4bgdC:
undetectable		 5vuoA-4bgdC:
20.99
5vuoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5vuoA-4bgdC:
undetectable
5vuoB-4bgdC:
undetectable		 5vuoA-4bgdC:
20.99
5vuoB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 5vupA-4bgdC:
undetectable
5vupB-4bgdC:
undetectable		 5vupA-4bgdC:
20.99
5vupB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 5vuqA-4bgdC:
undetectable
5vuqB-4bgdC:
undetectable		 5vuqA-4bgdC:
20.99
5vuqB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5vuqA-4bgdC:
undetectable
5vuqB-4bgdC:
undetectable		 5vuqA-4bgdC:
20.99
5vuqB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5vurA-4bgdC:
undetectable
5vurB-4bgdC:
undetectable		 5vurA-4bgdC:
20.99
5vurB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 5vusA-4bgdC:
undetectable
5vusB-4bgdC:
undetectable		 5vusA-4bgdC:
20.99
5vusB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 5vutA-4bgdC:
undetectable
5vutB-4bgdC:
undetectable		 5vutA-4bgdC:
20.99
5vutB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 5vuuA-4bgdC:
undetectable
5vuuB-4bgdC:
undetectable		 5vuuA-4bgdC:
20.99
5vuuB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 5vuuA-4bgdC:
undetectable
5vuuB-4bgdC:
undetectable		 5vuuA-4bgdC:
20.99
5vuuB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 5vuvA-4bgdC:
undetectable
5vuvB-4bgdC:
undetectable		 5vuvA-4bgdC:
20.63
5vuvB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 5vuvA-4bgdC:
undetectable
5vuvB-4bgdC:
undetectable		 5vuvA-4bgdC:
20.63
5vuvB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.29A 5vuwA-4bgdC:
undetectable
5vuwB-4bgdC:
undetectable		 5vuwA-4bgdC:
20.63
5vuwB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 5vuwA-4bgdC:
undetectable
5vuwB-4bgdC:
undetectable		 5vuwA-4bgdC:
20.63
5vuwB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 5vuxA-4bgdC:
undetectable
5vuxB-4bgdC:
undetectable		 5vuxA-4bgdC:
20.63
5vuxB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 5vuyA-4bgdC:
undetectable
5vuyB-4bgdC:
undetectable		 5vuyA-4bgdC:
20.63
5vuyB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 5vuyA-4bgdC:
undetectable
5vuyB-4bgdC:
undetectable		 5vuyA-4bgdC:
20.63
5vuyB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 5vuzA-4bgdC:
undetectable
5vuzB-4bgdC:
undetectable		 5vuzA-4bgdC:
20.63
5vuzB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5vuzA-4bgdC:
undetectable
5vuzB-4bgdC:
undetectable		 5vuzA-4bgdC:
20.63
5vuzB-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 5vv0A-4bgdC:
undetectable
5vv0B-4bgdC:
undetectable		 5vv0A-4bgdC:
21.12
5vv0B-4bgdC:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 5vv0A-4bgdC:
undetectable
5vv0B-4bgdC:
undetectable		 5vv0A-4bgdC:
21.12
5vv0B-4bgdC:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 5vv1A-4bgdC:
undetectable
5vv1B-4bgdC:
undetectable		 5vv1A-4bgdC:
20.63
5vv1B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 5vv1A-4bgdC:
undetectable
5vv1B-4bgdC:
undetectable		 5vv1A-4bgdC:
20.63
5vv1B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 5vv2A-4bgdC:
undetectable
5vv2B-4bgdC:
undetectable		 5vv2A-4bgdC:
20.63
5vv2B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 5vv2A-4bgdC:
undetectable
5vv2B-4bgdC:
undetectable		 5vv2A-4bgdC:
20.63
5vv2B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.34A 5vv3A-4bgdC:
undetectable
5vv3B-4bgdC:
undetectable		 5vv3A-4bgdC:
20.63
5vv3B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.29A 5vv3A-4bgdC:
undetectable
5vv3B-4bgdC:
undetectable		 5vv3A-4bgdC:
20.63
5vv3B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 5vv4A-4bgdC:
undetectable
5vv4B-4bgdC:
undetectable		 5vv4A-4bgdC:
20.63
5vv4B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 5vv5A-4bgdC:
undetectable
5vv5B-4bgdC:
undetectable		 5vv5A-4bgdC:
20.63
5vv5B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.26A 5vv5A-4bgdC:
undetectable
5vv5B-4bgdC:
undetectable		 5vv5A-4bgdC:
20.63
5vv5B-4bgdC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1471_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 12 GLY C2245
LEU C2247
TYR C2208
ASN C2348
THR C2223
 None
 1.19A 5x7pB-4bgdC:
undetectable		 5x7pB-4bgdC:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.34A 6auqA-4bgdC:
undetectable
6auqB-4bgdC:
undetectable		 6auqA-4bgdC:
14.35
6auqB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.35A 6auqA-4bgdC:
undetectable
6auqB-4bgdC:
undetectable		 6auqA-4bgdC:
14.35
6auqB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 6aurA-4bgdC:
undetectable
6aurB-4bgdC:
undetectable		 6aurA-4bgdC:
14.35
6aurB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 6aurA-4bgdC:
undetectable
6aurB-4bgdC:
undetectable		 6aurA-4bgdC:
14.35
6aurB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 6ausA-4bgdC:
undetectable
6ausB-4bgdC:
undetectable		 6ausA-4bgdC:
14.35
6ausB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 6autA-4bgdC:
undetectable
6autB-4bgdC:
undetectable		 6autA-4bgdC:
14.35
6autB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 6auuA-4bgdC:
undetectable
6auuB-4bgdC:
undetectable		 6auuA-4bgdC:
14.35
6auuB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 6auuA-4bgdC:
undetectable
6auuB-4bgdC:
undetectable		 6auuA-4bgdC:
14.35
6auuB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 6auvA-4bgdC:
undetectable
6auvB-4bgdC:
undetectable		 6auvA-4bgdC:
14.35
6auvB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 6auvA-4bgdC:
undetectable
6auvB-4bgdC:
undetectable		 6auvA-4bgdC:
14.35
6auvB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 6auwA-4bgdC:
undetectable
6auwB-4bgdC:
undetectable		 6auwA-4bgdC:
14.35
6auwB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 6auwA-4bgdC:
undetectable
6auwB-4bgdC:
undetectable		 6auwA-4bgdC:
14.35
6auwB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.35A 6auxA-4bgdC:
undetectable
6auxB-4bgdC:
undetectable		 6auxA-4bgdC:
14.35
6auxB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.34A 6auxA-4bgdC:
undetectable
6auxB-4bgdC:
undetectable		 6auxA-4bgdC:
14.35
6auxB-4bgdC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 6auyA-4bgdC:
undetectable
6auyB-4bgdC:
undetectable		 6auyA-4bgdC:
13.49
6auyB-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 6auyA-4bgdC:
undetectable
6auyB-4bgdC:
undetectable		 6auyA-4bgdC:
13.49
6auyB-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 6auzA-4bgdC:
undetectable
6auzB-4bgdC:
undetectable		 6auzA-4bgdC:
13.49
6auzB-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 6av0A-4bgdC:
undetectable
6av0B-4bgdC:
undetectable		 6av0A-4bgdC:
13.49
6av0B-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 6av0A-4bgdC:
undetectable
6av0B-4bgdC:
undetectable		 6av0A-4bgdC:
13.49
6av0B-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 6av1A-4bgdC:
undetectable
6av1B-4bgdC:
undetectable		 6av1A-4bgdC:
13.49
6av1B-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 6av2A-4bgdC:
undetectable
6av2B-4bgdC:
undetectable		 6av2A-4bgdC:
13.49
6av2B-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 6av2A-4bgdC:
undetectable
6av2B-4bgdC:
undetectable		 6av2A-4bgdC:
13.49
6av2B-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 6av3A-4bgdC:
undetectable
6av3B-4bgdC:
undetectable		 6av3A-4bgdC:
13.49
6av3B-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.28A 6av3A-4bgdC:
undetectable
6av3B-4bgdC:
undetectable		 6av3A-4bgdC:
13.49
6av3B-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.30A 6av4A-4bgdC:
undetectable
6av4B-4bgdC:
undetectable		 6av4A-4bgdC:
13.49
6av4B-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.31A 6av4A-4bgdC:
undetectable
6av4B-4bgdC:
undetectable		 6av4A-4bgdC:
13.49
6av4B-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.32A 6av5A-4bgdC:
undetectable
6av5B-4bgdC:
undetectable		 6av5A-4bgdC:
13.49
6av5B-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 6av5A-4bgdC:
undetectable
6av5B-4bgdC:
undetectable		 6av5A-4bgdC:
13.49
6av5B-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 5 VAL C2356
TRP C2357
PRO C2379
THR C2360
 None
 1.24A 6cduI-4bgdC:
undetectable
6cduJ-4bgdC:
undetectable		 6cduI-4bgdC:
20.47
6cduJ-4bgdC:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.33A 6cicA-4bgdC:
undetectable
6cicB-4bgdC:
undetectable		 6cicA-4bgdC:
13.49
6cicB-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.30A 6cicA-4bgdC:
undetectable
6cicB-4bgdC:
undetectable		 6cicA-4bgdC:
13.49
6cicB-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL C2274
TRP C2314
PHE C2329
GLU C2310
 None
 1.31A 6cidA-4bgdC:
undetectable
6cidB-4bgdC:
undetectable		 6cidA-4bgdC:
13.49
6cidB-4bgdC:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bgd PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 TRP C2314
PHE C2329
GLU C2310
VAL C2274
 None
 1.32A 6cidA-4bgdC:
undetectable
6cidB-4bgdC:
undetectable		 6cidA-4bgdC:
13.49
6cidB-4bgdC:
13.49