SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bgj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 4bgj SORTING NEXIN-14
(Homo
sapiens) 		4 / 4 GLU A 556
ARG A 548
ASN A 546
ASP A 547
 None
 1.43A 2zq9A-4bgjA:
undetectable		 2zq9A-4bgjA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 4bgj SORTING NEXIN-14
(Homo
sapiens) 		5 / 10 ALA A 627
LEU A 626
LEU A 615
VAL A 543
ILE A 514
 None
 1.06A 5v02B-4bgjA:
undetectable
5v02R-4bgjA:
undetectable		 5v02B-4bgjA:
20.14
5v02R-4bgjA:
16.77