SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bhc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 123
ALA A  50
ILE A  11
PRO A  10
LEU A 149
 None
 1.10A 1dhfA-4bhcA:
undetectable		 1dhfA-4bhcA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 123
ALA A  50
ILE A  11
PRO A  10
LEU A 149
 None
 1.24A 1dlsA-4bhcA:
undetectable		 1dlsA-4bhcA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 TYR A  89
TYR A  57
ARG A 128
GLY A  90
 None
 1.14A 1kifA-4bhcA:
undetectable		 1kifA-4bhcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 TYR A  89
TYR A  57
ARG A 128
GLY A  90
 None
 1.14A 1kifB-4bhcA:
undetectable		 1kifB-4bhcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 TYR A  89
TYR A  57
ARG A 128
GLY A  90
 None
 1.14A 1kifC-4bhcA:
undetectable		 1kifC-4bhcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 TYR A  89
TYR A  57
ARG A 128
GLY A  90
 None
 1.14A 1kifD-4bhcA:
undetectable		 1kifD-4bhcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 TYR A  89
TYR A  57
ARG A 128
GLY A  90
 None
 1.14A 1kifE-4bhcA:
undetectable		 1kifE-4bhcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 TYR A  89
TYR A  57
ARG A 128
GLY A  90
 None
 1.14A 1kifF-4bhcA:
undetectable		 1kifF-4bhcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 TYR A  89
TYR A  57
ARG A 128
GLY A  90
 None
 1.14A 1kifG-4bhcA:
undetectable		 1kifG-4bhcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 TYR A  89
TYR A  57
ARG A 128
GLY A  90
 None
 1.13A 1kifH-4bhcA:
undetectable		 1kifH-4bhcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 123
ALA A  50
ILE A  11
PRO A  10
LEU A 149
 None
 1.16A 2w3bB-4bhcA:
undetectable		 2w3bB-4bhcA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 4bhc METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 123
ALA A  50
ILE A  11
PRO A  10
LEU A 149
 None
 1.12A 2w3mA-4bhcA:
undetectable		 2w3mA-4bhcA:
20.51