SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bhh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 4bhh NUCLEOPROTEIN
(California
encephalitis
orthobunyavirus) 		3 / 3 ASN B  30
PHE B  65
VAL B  70
 None
 0.86A 1kijA-4bhhB:
undetectable		 1kijA-4bhhB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 4bhh NUCLEOPROTEIN
(California
encephalitis
orthobunyavirus) 		5 / 11 PHE B 152
SER B  33
ALA B  38
ARG B 101
LEU B  99
 None
 1.31A 2v0mA-4bhhB:
undetectable		 2v0mA-4bhhB:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4bhh NUCLEOPROTEIN
(California
encephalitis
orthobunyavirus) 		4 / 8 ILE B 163
GLY B 164
LEU B 178
LEU B 182
 None
 0.89A 2vctC-4bhhB:
undetectable		 2vctC-4bhhB:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 4bhh NUCLEOPROTEIN
(California
encephalitis
orthobunyavirus) 		5 / 12 PHE B  42
LEU B  99
VAL B  72
LEU B  90
ARG B  94
 None
None
None
None
U  R  16 ( 4.0A)
 1.33A 4po0A-4bhhB:
undetectable		 4po0A-4bhhB:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4bhh NUCLEOPROTEIN
(California
encephalitis
orthobunyavirus) 		4 / 6 GLY B  97
PHE B  42
ILE B  92
PHE B  65
 None
 1.04A 4qogA-4bhhB:
undetectable
4qogB-4bhhB:
undetectable		 4qogA-4bhhB:
20.00
4qogB-4bhhB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 4bhh NUCLEOPROTEIN
(California
encephalitis
orthobunyavirus) 		3 / 3 ASP B   3
ARG B  81
PRO B  78
 None
U  R  17 ( 4.1A)
None
 1.00A 4wanC-4bhhB:
undetectable		 4wanC-4bhhB:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 4bhh NUCLEOPROTEIN
(California
encephalitis
orthobunyavirus) 		3 / 3 GLY B  16
ASN B  15
ARG B  94
 U  R  14 ( 4.1A)
U  R  15 ( 2.8A)
U  R  16 ( 4.0A)
 0.77A 5w7bD-4bhhB:
undetectable		 5w7bD-4bhhB:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 4bhh NUCLEOPROTEIN
(California
encephalitis
orthobunyavirus) 		4 / 6 PHE B 146
PRO B 147
GLY B 148
THR B 149
 None
 0.84A 5x24A-4bhhB:
undetectable		 5x24A-4bhhB:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4bhh NUCLEOPROTEIN
(California
encephalitis
orthobunyavirus) 		5 / 12 GLY B 148
HIS B  93
SER B 205
VAL B 209
ILE B 163
 None
 1.34A 6bxnB-4bhhB:
undetectable		 6bxnB-4bhhB:
22.19