SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bhk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4bhk FLORICAULA/LEAFY
HOMOLOG 1
(Physcomitrella
patens) 		3 / 3 LEU A 305
PRO A 304
LEU A 308
 None
 0.53A 2po7B-4bhkA:
undetectable		 2po7B-4bhkA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4bhk FLORICAULA/LEAFY
HOMOLOG 1
(Physcomitrella
patens) 		3 / 3 LEU A 305
PRO A 304
LEU A 308
 None
 0.53A 3hcrA-4bhkA:
undetectable		 3hcrA-4bhkA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4bhk FLORICAULA/LEAFY
HOMOLOG 1
(Physcomitrella
patens) 		5 / 12 LEU A 283
ALA A 271
GLN A 299
PRO A 332
ARG A 264
 None
 1.33A 5syfB-4bhkA:
undetectable		 5syfB-4bhkA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 4bhk FLORICAULA/LEAFY
HOMOLOG 1
(Physcomitrella
patens) 		4 / 6 GLN A 299
GLU A 292
TRP A 297
ALA A 300
 None
 1.22A 6f6jC-4bhkA:
undetectable
6f6jD-4bhkA:
undetectable		 6f6jC-4bhkA:
19.32
6f6jD-4bhkA:
19.32