SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bhl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		3 / 3 ARG A 124
VAL A 220
TRP A 221
 None
 0.86A 1qw6A-4bhlA:
undetectable		 1qw6A-4bhlA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		3 / 3 ARG A 124
VAL A 220
TRP A 221
 None
 0.83A 1qwcA-4bhlA:
undetectable		 1qwcA-4bhlA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		4 / 8 TRP A 221
ASP A 192
LEU A 195
GLY A 191
 None
 0.76A 1rtsA-4bhlA:
undetectable		 1rtsA-4bhlA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		3 / 3 ARG A 124
VAL A 220
TRP A 221
 None
 0.85A 1vagA-4bhlA:
undetectable		 1vagA-4bhlA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		3 / 3 ARG A 124
VAL A 220
TRP A 221
 None
 0.78A 1zviA-4bhlA:
undetectable		 1zviA-4bhlA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		3 / 3 ASN A 274
ARG A 330
ASP A 324
 ARG  A 400 ( 4.5A)
None
None
 0.93A 2qe6A-4bhlA:
undetectable		 2qe6A-4bhlA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		4 / 5 ILE A  86
HIS A  90
TYR A  75
GLY A 276
 None
 1.17A 3b9mA-4bhlA:
undetectable		 3b9mA-4bhlA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		5 / 12 PHE A 136
MET A 331
THR A 278
LEU A  26
ILE A  86
 None
 1.37A 3em0B-4bhlA:
undetectable		 3em0B-4bhlA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		4 / 8 TYR A 211
ASN A 213
ASP A 214
LEU A 159
 None
 0.99A 4f8hA-4bhlA:
undetectable
4f8hB-4bhlA:
undetectable		 4f8hA-4bhlA:
23.48
4f8hB-4bhlA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		5 / 10 PHE A 110
ASP A 106
PHE A 243
SER A 109
GLY A 240
 None
 1.36A 4xp1A-4bhlA:
undetectable		 4xp1A-4bhlA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		4 / 6 SER A 174
GLU A 176
GLY A 207
GLY A 209
 None
 0.72A 5cdnC-4bhlA:
1.4
5cdnD-4bhlA:
undetectable		 5cdnC-4bhlA:
21.48
5cdnD-4bhlA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		4 / 6 SER A 174
GLU A 176
GLY A 207
GLY A 209
 None
 0.70A 5cdnT-4bhlA:
undetectable
5cdnU-4bhlA:
undetectable		 5cdnT-4bhlA:
21.48
5cdnU-4bhlA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		4 / 6 TYR A  89
TYR A  75
GLY A  66
ASP A  62
 None
None
ARG  A 400 (-3.8A)
None
 1.16A 5emlA-4bhlA:
undetectable		 5emlA-4bhlA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		5 / 12 VAL A  35
PHE A  36
ILE A  54
TYR A  75
ALA A  69
 None
 0.94A 5fctB-4bhlA:
undetectable		 5fctB-4bhlA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		3 / 3 ARG A 124
VAL A 220
TRP A 221
 None
 0.82A 5fvoA-4bhlA:
undetectable		 5fvoA-4bhlA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		4 / 7 LEU A 159
ILE A 230
LEU A 246
MET A 233
 None
 1.03A 5fxtA-4bhlA:
undetectable		 5fxtA-4bhlA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		5 / 10 VAL A 283
ILE A 285
LEU A 287
PHE A 119
GLY A 345
 None
 0.83A 5mxbA-4bhlA:
0.9		 5mxbA-4bhlA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		3 / 3 THR A 166
HIS A 212
ASN A 213
 None
 0.93A 5n4tA-4bhlA:
undetectable		 5n4tA-4bhlA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 4bhl ARGININE KINASE
(Litopenaeus
vannamei) 		5 / 12 VAL A 250
PHE A 104
THR A 277
GLY A 276
GLY A 266
 None
 0.99A 6brdB-4bhlA:
1.0		 6brdB-4bhlA:
13.18