SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bhy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4bhy ALANINE RACEMASE
(Aeromonas
hydrophila) 		4 / 5 ASN A   9
ALA A  12
ALA A  11
ARG A  14
 None
 1.11A 3kp2B-4bhyA:
undetectable		 3kp2B-4bhyA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 4bhy ALANINE RACEMASE
(Aeromonas
hydrophila) 		5 / 12 VAL A 289
LEU A 240
GLY A 312
ALA A 313
LEU A 309
 None
 1.16A 3pghA-4bhyA:
undetectable		 3pghA-4bhyA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4bhy ALANINE RACEMASE
(Aeromonas
hydrophila) 		3 / 3 ARG A 265
ARG A 292
ASP A 319
 None
 1.00A 3wipG-4bhyA:
undetectable
3wipH-4bhyA:
undetectable		 3wipG-4bhyA:
19.55
3wipH-4bhyA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 4bhy ALANINE RACEMASE
(Aeromonas
hydrophila) 		3 / 3 TRP A 324
GLN A 231
THR A 235
 None
 1.01A 4m2xA-4bhyA:
undetectable		 4m2xA-4bhyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 4bhy ALANINE RACEMASE
(Aeromonas
hydrophila) 		4 / 4 VAL A 307
ILE A 293
ASN A 290
VAL A 322
 None
 1.18A 5ajqA-4bhyA:
undetectable		 5ajqA-4bhyA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 4bhy ALANINE RACEMASE
(Aeromonas
hydrophila) 		4 / 7 TYR A 273
ALA A 256
GLY A 253
TYR A 254
 None
 0.97A 5uxdA-4bhyA:
undetectable		 5uxdA-4bhyA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4bhy ALANINE RACEMASE
(Aeromonas
hydrophila) 		6 / 12 LEU A 348
GLY A  41
VAL A 233
ILE A   8
MET A 234
LEU A  66
 None
 1.40A 5ycnA-4bhyA:
undetectable		 5ycnA-4bhyA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 4bhy ALANINE RACEMASE
(Aeromonas
hydrophila) 		5 / 12 ASP A 303
GLY A 276
GLY A 272
ARG A 351
SER A 350
 None
 1.30A 6clxA-4bhyA:
undetectable		 6clxA-4bhyA:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 4bhy ALANINE RACEMASE
(Aeromonas
hydrophila) 		3 / 3 TYR A 277
ALA A 281
LEU A 296
 None
 0.60A 6d9kF-4bhyA:
undetectable		 6d9kF-4bhyA:
21.74