SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4big'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 4big UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		4 / 6 LEU A 212
PHE A 232
TYR A  44
VAL A 195
 None
 1.27A 1ibgH-4bigA:
undetectable		 1ibgH-4bigA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4big UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		5 / 12 PHE A 153
PHE A 232
LEU A  41
ALA A 157
PHE A 156
 None
 1.50A 3apxA-4bigA:
undetectable		 3apxA-4bigA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 4big UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		3 / 3 PHE A 232
TYR A 186
LEU A 235
 None
 0.74A 3keeB-4bigA:
undetectable		 3keeB-4bigA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4big UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		3 / 3 PHE A 232
TYR A 186
LEU A 235
 None
 0.62A 3sueB-4bigA:
undetectable		 3sueB-4bigA:
20.93