SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bih'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 4bih UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		4 / 6 LEU A 211
PHE A 231
TYR A  43
VAL A 194
 None
 1.33A 1ibgH-4bihA:
undetectable		 1ibgH-4bihA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 4bih UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		5 / 11 GLY A 159
TYR A  43
PHE A 161
PHE A 243
PHE A 231
 None
 1.14A 1w76A-4bihA:
undetectable		 1w76A-4bihA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4bih UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		4 / 7 TYR A 125
VAL A 127
ILE A 134
GLU A 122
 None
 1.06A 4a97E-4bihA:
undetectable		 4a97E-4bihA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4bih UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		4 / 8 TYR A 125
VAL A 127
ILE A 134
GLU A 122
 None
 1.06A 4a97C-4bihA:
undetectable		 4a97C-4bihA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4bih UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		4 / 8 TYR A 125
VAL A 127
ILE A 134
GLU A 122
 None
 1.06A 4a97G-4bihA:
undetectable		 4a97G-4bihA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 4bih UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		4 / 6 ASN A 132
ILE A 135
ILE A 134
VAL A 127
 None
 1.01A 4olmA-4bihA:
undetectable		 4olmA-4bihA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4bih UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		4 / 5 TYR A 242
ALA A  87
GLN A  79
THR A 110
 None
 1.36A 5n4iA-4bihA:
undetectable		 5n4iA-4bihA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 4bih UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053
(Staphylococcus
aureus) 		3 / 3 ASP A 112
ASP A 108
ASN A  73
 None
 0.85A 6gngB-4bihA:
undetectable		 6gngB-4bihA:
19.04