SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bil'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		3 / 3 THR A 261
PRO A 263
THR A 259
 None
 0.78A 1dscC-4bilA:
undetectable		 1dscC-4bilA:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		3 / 3 ARG A 326
THR A 467
VAL A 464
 None
 0.98A 1hxbA-4bilA:
undetectable		 1hxbA-4bilA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		4 / 6 LEU A 402
THR A 401
LEU A 313
ASP A 459
 None
 1.11A 2wm3A-4bilA:
2.9		 2wm3A-4bilA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		3 / 3 THR A 261
PRO A 263
THR A 259
 None
 0.87A 316dC-4bilA:
undetectable		 316dC-4bilA:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		5 / 12 ILE A 221
ASN A 215
GLU A 175
TYR A 198
VAL A  45
 None
 1.44A 4a97A-4bilA:
undetectable
4a97B-4bilA:
undetectable		 4a97A-4bilA:
19.96
4a97B-4bilA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		4 / 7 ASP A 262
ASP A 250
GLU A 232
GLU A 254
 None
 1.12A 4fewB-4bilA:
undetectable		 4fewB-4bilA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		3 / 3 THR A 261
PRO A 263
THR A 259
 None
 0.87A 4hivD-4bilA:
undetectable		 4hivD-4bilA:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		3 / 3 CYH A  69
ASN A  97
LYS A  64
 None
 1.15A 4k50A-4bilA:
undetectable		 4k50A-4bilA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		3 / 3 ARG A 216
LEU A 212
GLU A 213
 None
 0.67A 4l3gF-4bilA:
0.8		 4l3gF-4bilA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		3 / 3 THR A 170
ASN A 167
SER A 168
 None
 0.78A 4tvtA-4bilA:
undetectable		 4tvtA-4bilA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		3 / 3 ARG A 368
GLN A 358
GLU A 389
 None
 0.89A 4tvtA-4bilA:
undetectable		 4tvtA-4bilA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		4 / 6 SER A 353
ASP A 312
ARG A 456
GLU A 454
 None
 0.90A 5cdqA-4bilA:
undetectable
5cdqC-4bilA:
undetectable
5cdqD-4bilA:
undetectable		 5cdqA-4bilA:
21.19
5cdqC-4bilA:
21.19
5cdqD-4bilA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		4 / 4 LEU A 323
LEU A 338
GLY A 337
GLU A 297
 None
 1.26A 5hhjA-4bilA:
undetectable		 5hhjA-4bilA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		4 / 6 ILE A 158
GLY A 144
MET A 171
ILE A  86
 None
 0.96A 5j4nB-4bilA:
undetectable		 5j4nB-4bilA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		4 / 8 GLU A 232
PRO A 263
GLY A  61
ASP A 262
 None
 1.11A 5kgpA-4bilA:
undetectable		 5kgpA-4bilA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 4bil DNA MATURASE B
(Escherichia
virus
T7) 		4 / 8 GLU A 232
PRO A 263
GLY A  61
ASP A 262
 None
 1.10A 5kgpB-4bilA:
undetectable		 5kgpB-4bilA:
20.91