SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bj4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 4bj4 AMPDH2
(Pseudomonas
aeruginosa) 		3 / 3 ALA A  87
VAL A  89
TRP A  97
 None
None
FLC  A1260 (-4.9A)
 0.79A 1av2C-4bj4A:
undetectable
1av2D-4bj4A:
undetectable		 1av2C-4bj4A:
7.48
1av2D-4bj4A:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 4bj4 AMPDH2
(Pseudomonas
aeruginosa) 		3 / 3 ALA A  87
VAL A  89
TRP A  97
 None
None
FLC  A1260 (-4.9A)
 0.79A 1w5uC-4bj4A:
undetectable
1w5uD-4bj4A:
undetectable		 1w5uC-4bj4A:
7.48
1w5uD-4bj4A:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4bj4 AMPDH2
(Pseudomonas
aeruginosa) 		4 / 7 ARG A 237
ALA A 251
PRO A 182
ALA A 255
 None
 1.05A 2ejfA-4bj4A:
undetectable		 2ejfA-4bj4A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 4bj4 AMPDH2
(Pseudomonas
aeruginosa) 		5 / 10 ILE A 105
PHE A 168
LEU A 178
VAL A 179
LEU A 173
 None
 1.40A 2w98A-4bj4A:
undetectable		 2w98A-4bj4A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 4bj4 AMPDH2
(Pseudomonas
aeruginosa) 		3 / 3 ALA A  87
VAL A  89
TRP A  97
 None
None
FLC  A1260 (-4.9A)
 0.81A 3l8lC-4bj4A:
undetectable
3l8lD-4bj4A:
undetectable		 3l8lC-4bj4A:
7.48
3l8lD-4bj4A:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 4bj4 AMPDH2
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  98
PHE A  38
GLU A  80
GLY A 104
VAL A  36
 None
 0.91A 3nk7B-4bj4A:
undetectable		 3nk7B-4bj4A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 4bj4 AMPDH2
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 219
THR A 218
GLN A 205
THR A 225
 None
 0.93A 3rglA-4bj4A:
undetectable		 3rglA-4bj4A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4bj4 AMPDH2
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 163
ARG A 160
LYS A 161
 None
 0.98A 3wipG-4bj4A:
undetectable		 3wipG-4bj4A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 4bj4 AMPDH2
(Pseudomonas
aeruginosa) 		5 / 12 TRP A  92
ILE A 139
HIS A 143
GLY A 104
ILE A 105
 None
 0.98A 5d4uD-4bj4A:
undetectable		 5d4uD-4bj4A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 4bj4 AMPDH2
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 230
ALA A 231
ASP A 155
GLY A 165
 None
 0.59A 5kr1B-4bj4A:
undetectable		 5kr1B-4bj4A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 4bj4 AMPDH2
(Pseudomonas
aeruginosa) 		3 / 3 TYR A  43
PRO A 166
LEU A 167
 None
 0.92A 6beoA-4bj4A:
undetectable		 6beoA-4bj4A:
3.51