SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 4bji TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		4 / 4 LEU A 252
ARG A 232
LEU A 228
ALA A 239
 None
 1.13A 3b9mA-4bjiA:
undetectable		 3b9mA-4bjiA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 4bji TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A 364
ILE A 331
THR A 338
 None
 0.54A 3ia4D-4bjiA:
undetectable		 3ia4D-4bjiA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 4bji TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		4 / 8 TYR A 321
ASP A 310
ASP A 328
LEU A 367
 None
 1.08A 4f8hA-4bjiA:
undetectable
4f8hB-4bjiA:
undetectable		 4f8hA-4bjiA:
21.23
4f8hB-4bjiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 4bji TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		4 / 8 TYR A 321
ASP A 310
ASP A 328
LEU A 367
 None
 1.09A 4f8hC-4bjiA:
undetectable
4f8hD-4bjiA:
undetectable		 4f8hC-4bjiA:
21.23
4f8hD-4bjiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 4bji TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		4 / 8 TYR A 321
ASP A 310
ASP A 328
LEU A 367
 None
 1.07A 4f8hD-4bjiA:
undetectable
4f8hE-4bjiA:
undetectable		 4f8hD-4bjiA:
21.23
4f8hE-4bjiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 4bji TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		4 / 8 LEU A 367
TYR A 321
ASP A 310
ASP A 328
 None
 1.09A 4f8hA-4bjiA:
undetectable
4f8hE-4bjiA:
undetectable		 4f8hA-4bjiA:
21.23
4f8hE-4bjiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4bji TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		5 / 9 VAL A 359
LEU A 362
LEU A 291
ALA A 332
LEU A 335
 None
 1.05A 4rs0A-4bjiA:
undetectable		 4rs0A-4bjiA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 4bji TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		4 / 5 THR A 236
HIS A 307
HIS A 243
ARG A 232
 None
 1.49A 6dchA-4bjiA:
undetectable		 6dchA-4bjiA:
19.49