SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bjj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4bjj TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
TRANSCRIPTION FACTOR
TAU SUBUNIT SFC7
(Schizosaccharomy
ces
pombe;
Schizosaccharomy
ces
pombe) 		4 / 5 TYR A  11
SER A   7
SER A  91
ASN B  72
 None
 1.19A 1yvpA-4bjjA:
undetectable		 1yvpA-4bjjA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4bjj TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
TRANSCRIPTION FACTOR
TAU SUBUNIT SFC7
(Schizosaccharomy
ces
pombe;
Schizosaccharomy
ces
pombe) 		4 / 6 TYR A  11
SER A   7
SER A  91
ASN B  72
 None
 1.16A 1yvpB-4bjjA:
undetectable		 1yvpB-4bjjA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 4bjj TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		4 / 7 SER A   7
ASP A   8
SER A  91
ASN A  89
 None
 0.98A 2cmlA-4bjjA:
undetectable		 2cmlA-4bjjA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 4bjj TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		4 / 8 SER A   7
ASP A   8
SER A  91
ASN A  89
 None
 0.91A 2cmlB-4bjjA:
undetectable		 2cmlB-4bjjA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 4bjj TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		4 / 8 SER A   7
ASP A   8
SER A  91
ASN A  89
 None
 1.00A 2cmlC-4bjjA:
undetectable		 2cmlC-4bjjA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 4bjj TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
(Schizosaccharomy
ces
pombe) 		4 / 8 SER A   7
ASP A   8
SER A  91
ASN A  89
 None
 0.97A 2cmlD-4bjjA:
undetectable		 2cmlD-4bjjA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4bjj TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1
TRANSCRIPTION FACTOR
TAU SUBUNIT SFC7
(Schizosaccharomy
ces
pombe) 		3 / 3 LEU A  77
LEU B  90
MET B  89
 None
 0.85A 2itzA-4bjjA:
undetectable		 2itzA-4bjjA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 4bjj TRANSCRIPTION FACTOR
TAU SUBUNIT SFC7
(Schizosaccharomy
ces
pombe) 		4 / 5 GLY B  50
GLY B  51
PHE B  22
PHE B  54
 None
 0.98A 2qr2A-4bjjB:
undetectable
2qr2B-4bjjB:
undetectable		 2qr2A-4bjjB:
17.26
2qr2B-4bjjB:
17.26