SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bjt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
4 / 7 ILE A 746
GLY A 745
PHE A 716
PHE A 773
None
0.95A 2vctD-4bjtA:
undetectable
2vctD-4bjtA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
4 / 7 TYR A 768
PHE A 769
PHE A 703
ILE A 754
None
1.24A 2zseA-4bjtA:
undetectable
2zseA-4bjtA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
4 / 8 ILE A 746
PHE A 769
THR A 756
LEU A 755
None
0.92A 3ablN-4bjtA:
undetectable
3ablW-4bjtA:
undetectable
3ablN-4bjtA:
18.11
3ablW-4bjtA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
4 / 6 PHE A 769
MET A 717
PHE A 716
PHE A 707
None
1.43A 3af3A-4bjtA:
undetectable
3af3A-4bjtA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
4 / 8 ILE A 746
PHE A 769
THR A 756
LEU A 755
None
0.91A 3ag3N-4bjtA:
undetectable
3ag3W-4bjtA:
undetectable
3ag3N-4bjtA:
18.11
3ag3W-4bjtA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
5 / 12 VAL A 783
ILE A 786
PHE A 716
LEU A 720
PHE A 773
None
1.42A 3apwB-4bjtA:
undetectable
3apwB-4bjtA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
4 / 7 PRO A 766
LEU A 758
LEU A 755
ILE A 724
None
0.95A 3u5jA-4bjtA:
undetectable
3u5jA-4bjtA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
4 / 7 ILE A 746
PHE A 769
THR A 756
LEU A 755
None
0.92A 5b1bN-4bjtA:
undetectable
5b1bW-4bjtA:
undetectable
5b1bN-4bjtA:
18.11
5b1bW-4bjtA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
4 / 7 ILE A 746
PHE A 769
THR A 756
LEU A 755
None
0.93A 5b3sN-4bjtA:
undetectable
5b3sW-4bjtA:
undetectable
5b3sN-4bjtA:
18.11
5b3sW-4bjtA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
4 / 7 ILE A 746
PHE A 769
THR A 756
LEU A 755
None
0.94A 5iy5N-4bjtA:
undetectable
5iy5W-4bjtA:
undetectable
5iy5N-4bjtA:
18.11
5iy5W-4bjtA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
4 / 8 ILE A 746
PHE A 769
THR A 756
LEU A 755
None
0.91A 5xdxN-4bjtA:
undetectable
5xdxW-4bjtA:
undetectable
5xdxN-4bjtA:
18.11
5xdxW-4bjtA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4bjt DNA-BINDING PROTEIN
RAP1

(Saccharomyces
cerevisiae)
4 / 8 ILE A 746
PHE A 769
THR A 756
LEU A 755
None
0.94A 5zcqN-4bjtA:
undetectable
5zcqW-4bjtA:
undetectable
5zcqN-4bjtA:
18.11
5zcqW-4bjtA:
14.67