SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bkm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DVX_B_DIFB125_2 (TRANSTHYRETIN)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 7	ALA A 92 LEU A 90 SER A 87 VAL A 156	None	1.02A	1dvxB-4bkmA: undetectable	1dvxB-4bkmA: 15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_A_CCSA47_0 (GLUTATHIONE S-TRANSFERASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 7	LEU A 16 LEU A 23 GLY A 21 LEU A 47	None	0.82A	1gtiA-4bkmA: undetectable	1gtiA-4bkmA: 19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWI_C_115C4_1 (HMG-COA REDUCTASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 7	VAL A 57 SER A 58 ASN A 60 ASP A 27	None None NO3 A1305 ( 4.4A) None	1.36A	1hwiC-4bkmA: undetectable	1hwiC-4bkmA: 22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWI_D_115D3_2 (HMG-COA REDUCTASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 7	VAL A 57 SER A 58 ASN A 60 ASP A 27	None None NO3 A1305 ( 4.4A) None	1.36A	1hwiD-4bkmA: undetectable	1hwiD-4bkmA: 22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_A_ADNA1237_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 11	MET A 244 THR A 251 GLY A 221 ASN A 59 ILE A 220	None	1.48A	1odiA-4bkmA: undetectable	1odiA-4bkmA: 24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_B_ADNB1237_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 11	MET A 244 THR A 251 GLY A 221 ASN A 59 ILE A 220	None	1.44A	1odiB-4bkmA: undetectable	1odiB-4bkmA: 24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_C_ADNC1238_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 11	MET A 244 THR A 251 GLY A 221 ASN A 59 ILE A 220	None	1.47A	1odiC-4bkmA: undetectable	1odiC-4bkmA: 24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_D_ADND1237_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 11	MET A 244 THR A 251 GLY A 221 ASN A 59 ILE A 220	None	1.50A	1odiD-4bkmA: undetectable	1odiD-4bkmA: 24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_E_ADNE1237_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 11	MET A 244 THR A 251 GLY A 221 ASN A 59 ILE A 220	None	1.42A	1odiE-4bkmA: undetectable	1odiE-4bkmA: 24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_F_ADNF1238_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 11	MET A 244 THR A 251 GLY A 221 ASN A 59 ILE A 220	None	1.47A	1odiF-4bkmA: undetectable	1odiF-4bkmA: 24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YVP_B_ACTB2002_0 (60-KDA SS-A/RO RIBONUCLEOPROTEIN)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 6	SER A 88 ALA A 89 SER A 61 THR A 185	NO3 A1305 ( 4.6A) None NO3 A1305 (-2.3A) NO3 A1305 ( 4.8A)	1.16A	1yvpB-4bkmA: 2.2	1yvpB-4bkmA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1502_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 5	PRO A 192 GLY A 33 ASN A 32 GLY A 28	None None None MG A1304 ( 4.7A)	0.89A	1zlqA-4bkmA: undetectable	1zlqA-4bkmA: 21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXG_A_IBPA2001_1 (SERUM ALBUMIN)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 11	VAL A 183 GLY A 184 ALA A 92 LEU A 96 SER A 127	None	1.08A	2bxgA-4bkmA: undetectable	2bxgA-4bkmA: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CPP_A_CAMA422_0 (CYTOCHROME P450-CAM)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 7	THR A 262 LEU A 12 VAL A 15 VAL A 22	None	0.88A	2cppA-4bkmA: undetectable	2cppA-4bkmA: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CPP_A_CAMA422_0 (CYTOCHROME P450-CAM)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 7	THR A 262 LEU A 12 VAL A 15 VAL A 245	None	1.03A	2cppA-4bkmA: undetectable	2cppA-4bkmA: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_D_KLND1499_1 (CYTOCHROME P450 3A4)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 5	PHE A 235 PHE A 72 PHE A 86 ILE A 296	None	1.24A	2v0mD-4bkmA: undetectable	2v0mD-4bkmA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_B_2FAB500_2 (ADENOSYLHOMOCYSTEINA SE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 5	LEU A 249 GLN A 277 THR A 263 HIS A 257	None	1.34A	2zj0B-4bkmA: 2.3	2zj0B-4bkmA: 22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_C_2FAC500_2 (ADENOSYLHOMOCYSTEINA SE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 5	LEU A 249 GLN A 277 THR A 263 HIS A 257	None	1.25A	2zj0C-4bkmA: 3.7	2zj0C-4bkmA: 22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_B_ADNB500_2 (ADENOSYLHOMOCYSTEINA SE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 5	LEU A 249 GLN A 277 THR A 263 HIS A 257	None	1.32A	3ce6B-4bkmA: 2.1	3ce6B-4bkmA: 21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D2T_B_1FLB500_1 (TRANSTHYRETIN)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 6	ALA A 92 LEU A 90 SER A 87 VAL A 156	None	1.06A	3d2tB-4bkmA: undetectable	3d2tB-4bkmA: 16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LS4_H_TCIH220_1 (HEAVY CHAIN OF ANTIBODY FAB FRAGMENT)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 10	VAL A 130 VAL A 110 SER A 127 GLY A 112 GLY A 158	None	0.89A	3ls4H-4bkmA: undetectable	3ls4H-4bkmA: 21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OZK_B_T44B128_1 (TRANSTHYRETIN)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 7	ALA A 92 LEU A 90 SER A 87 VAL A 156	None	0.91A	3ozkB-4bkmA: undetectable	3ozkB-4bkmA: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AQ7_A_LEUA902_0 (LEUCINE--TRNA LIGASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 7	MET A 300 LEU A 299 SER A 295 GLU A 42	None	1.12A	4aq7A-4bkmA: undetectable	4aq7A-4bkmA: 16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KTT_A_SAMA405_0 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 8	HIS A 162 PRO A 161 ASP A 160 SER A 127	None	1.07A	4kttA-4bkmA: undetectable	4kttA-4bkmA: 22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L4A_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 8	THR A 262 LEU A 12 VAL A 15 VAL A 22	None	0.91A	4l4aA-4bkmA: undetectable	4l4aA-4bkmA: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L4D_A_CAMA503_0 (CAMPHOR 5-MONOOXYGENASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 8	THR A 262 LEU A 12 VAL A 15 VAL A 245	None	1.04A	4l4dA-4bkmA: undetectable	4l4dA-4bkmA: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NTX_A_AMRA509_1 (ACID-SENSING ION CHANNEL 1 BASIC PHOSPHOLIPASE A2 HOMOLOG TX-BETA)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 6	GLU A 34 GLU A 67 ASN A 60 ARG A 62	None None NO3 A1305 ( 4.4A) NO3 A1305 (-4.8A)	1.19A	4ntxA-4bkmA: undetectable 4ntxC-4bkmA: undetectable	4ntxA-4bkmA: 22.27 4ntxC-4bkmA: 17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ODJ_A_SAMA500_0 (S-ADENOSYLMETHIONINE SYNTHASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 7	HIS A 162 PRO A 161 ASP A 160 SER A 127	None	1.11A	4odjA-4bkmA: undetectable	4odjA-4bkmA: 20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UDC_A_DEXA1778_2 (GLUCOCORTICOID RECEPTOR)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	3 / 3	MET A 1 GLN A 284 TYR A 279	None	1.06A	4udcA-4bkmA: undetectable	4udcA-4bkmA: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNW_B_RTZB602_1 (CYTOCHROME P450 2D6)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 12	PHE A 77 LEU A 44 GLY A 246 SER A 295 VAL A 293	None	1.11A	4wnwB-4bkmA: undetectable	4wnwB-4bkmA: 22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A6I_A_TCWA1124_1 (TRANSTHYRETIN)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 6	ALA A 92 LEU A 90 SER A 87 VAL A 156	None	1.04A	5a6iA-4bkmA: undetectable	5a6iA-4bkmA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BW4_A_SAMA301_0 (16S RRNA (ADENINE(1408)-N(1)) -METHYLTRANSFERASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 12	GLY A 269 ASP A 247 ILE A 253 LEU A 273 LEU A 249	None MG A1304 (-2.1A) None None None	1.09A	5bw4A-4bkmA: undetectable	5bw4A-4bkmA: 26.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TIW_A_OAQA302_0 (SULFOTRANSFERASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 12	MET A 187 ILE A 219 VAL A 156 VAL A 157 LEU A 95	None	1.26A	5tiwA-4bkmA: undetectable	5tiwA-4bkmA: 21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUD_A_ERMA2001_1 (5-HYDROXYTRYPTAMINE RECEPTOR 2B,SOLUBLE CYTOCHROME B562 CHIMERA)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 12	LEU A 23 ALA A 40 PHE A 72 PHE A 77 LEU A 68	None	1.10A	5tudA-4bkmA: undetectable	5tudA-4bkmA: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCV_A_1N1A404_2 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 5	VAL A 103 LEU A 181 CYH A 180 ASP A 151	None	1.15A	5vcvA-4bkmA: undetectable	5vcvA-4bkmA: 23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B52_A_OAQA302_0 (SULFOTRANSFERASE)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	5 / 12	MET A 187 ILE A 219 VAL A 156 VAL A 157 LEU A 95	None	1.23A	6b52A-4bkmA: undetectable	6b52A-4bkmA: 21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_A_NOVA403_2 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 6	ARG A 97 LEU A 96 ALA A 108 GLN A 98	None	1.02A	6b89B-4bkmA: undetectable	6b89B-4bkmA: 15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBN_B_SAMB401_1 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	4bkm	PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE (Mus musculus)	4 / 8	HIS A 162 PRO A 161 ASP A 160 SER A 127	None	1.12A	6fbnB-4bkmA: undetectable	6fbnB-4bkmA: 22.85

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DVX_B_DIFB125_2","TRANSTHYRETIN","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"ALA A  92;LEU A  90;SER A  87;VAL A 156","None","1.02A","1dvxB-4bkmA:undetectable","1dvxB-4bkmA:15.69"],["1GTI_A_CCSA47_0","GLUTATHIONE S-TRANSFERASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"LEU A  16;LEU A  23;GLY A  21;LEU A  47","None","0.82A","1gtiA-4bkmA:undetectable","1gtiA-4bkmA:19.94"],["1HWI_C_115C4_1","HMG-COA REDUCTASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"VAL A  57;SER A  58;ASN A  60;ASP A  27","None;None;NO3 A1305 ( 4.4A);None","1.36A","1hwiC-4bkmA:undetectable","1hwiC-4bkmA:22.72"],["1HWI_D_115D3_2","HMG-COA REDUCTASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"VAL A  57;SER A  58;ASN A  60;ASP A  27","None;None;NO3 A1305 ( 4.4A);None","1.36A","1hwiD-4bkmA:undetectable","1hwiD-4bkmA:22.72"],["1ODI_A_ADNA1237_1","PURINE NUCLEOSIDE PHOSPHORYLASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"MET A 244;THR A 251;GLY A 221;ASN A  59;ILE A 220","None","1.48A","1odiA-4bkmA:undetectable","1odiA-4bkmA:24.46"],["1ODI_B_ADNB1237_1","PURINE NUCLEOSIDE PHOSPHORYLASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"MET A 244;THR A 251;GLY A 221;ASN A  59;ILE A 220","None","1.44A","1odiB-4bkmA:undetectable","1odiB-4bkmA:24.46"],["1ODI_C_ADNC1238_1","PURINE NUCLEOSIDE PHOSPHORYLASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"MET A 244;THR A 251;GLY A 221;ASN A  59;ILE A 220","None","1.47A","1odiC-4bkmA:undetectable","1odiC-4bkmA:24.46"],["1ODI_D_ADND1237_1","PURINE NUCLEOSIDE PHOSPHORYLASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"MET A 244;THR A 251;GLY A 221;ASN A  59;ILE A 220","None","1.50A","1odiD-4bkmA:undetectable","1odiD-4bkmA:24.46"],["1ODI_E_ADNE1237_1","PURINE NUCLEOSIDE PHOSPHORYLASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"MET A 244;THR A 251;GLY A 221;ASN A  59;ILE A 220","None","1.42A","1odiE-4bkmA:undetectable","1odiE-4bkmA:24.46"],["1ODI_F_ADNF1238_1","PURINE NUCLEOSIDE PHOSPHORYLASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"MET A 244;THR A 251;GLY A 221;ASN A  59;ILE A 220","None","1.47A","1odiF-4bkmA:undetectable","1odiF-4bkmA:24.46"],["1YVP_B_ACTB2002_0","60-KDA SS-A\/RO RIBONUCLEOPROTEIN","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"SER A  88;ALA A  89;SER A  61;THR A 185","NO3 A1305 ( 4.6A);None;NO3 A1305 (-2.3A);NO3 A1305 ( 4.8A)","1.16A","1yvpB-4bkmA:2.2","1yvpB-4bkmA:21.35"],["1ZLQ_A_ACTA1502_0","NICKEL-BINDING PERIPLASMIC PROTEIN","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"PRO A 192;GLY A  33;ASN A  32;GLY A  28","None;None;None; MG A1304 ( 4.7A)","0.89A","1zlqA-4bkmA:undetectable","1zlqA-4bkmA:21.64"],["2BXG_A_IBPA2001_1","SERUM ALBUMIN","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"VAL A 183;GLY A 184;ALA A  92;LEU A  96;SER A 127","None","1.08A","2bxgA-4bkmA:undetectable","2bxgA-4bkmA:19.39"],["2CPP_A_CAMA422_0","CYTOCHROME P450-CAM","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"THR A 262;LEU A  12;VAL A  15;VAL A  22","None","0.88A","2cppA-4bkmA:undetectable","2cppA-4bkmA:20.56"],["2CPP_A_CAMA422_0","CYTOCHROME P450-CAM","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"THR A 262;LEU A  12;VAL A  15;VAL A 245","None","1.03A","2cppA-4bkmA:undetectable","2cppA-4bkmA:20.56"],["2V0M_D_KLND1499_1","CYTOCHROME P450 3A4","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"PHE A 235;PHE A  72;PHE A  86;ILE A 296","None","1.24A","2v0mD-4bkmA:undetectable","2v0mD-4bkmA:21.60"],["2ZJ0_B_2FAB500_2","ADENOSYLHOMOCYSTEINASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"LEU A 249;GLN A 277;THR A 263;HIS A 257","None","1.34A","2zj0B-4bkmA:2.3","2zj0B-4bkmA:22.09"],["2ZJ0_C_2FAC500_2","ADENOSYLHOMOCYSTEINASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"LEU A 249;GLN A 277;THR A 263;HIS A 257","None","1.25A","2zj0C-4bkmA:3.7","2zj0C-4bkmA:22.09"],["3CE6_B_ADNB500_2","ADENOSYLHOMOCYSTEINASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"LEU A 249;GLN A 277;THR A 263;HIS A 257","None","1.32A","3ce6B-4bkmA:2.1","3ce6B-4bkmA:21.51"],["3D2T_B_1FLB500_1","TRANSTHYRETIN","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"ALA A  92;LEU A  90;SER A  87;VAL A 156","None","1.06A","3d2tB-4bkmA:undetectable","3d2tB-4bkmA:16.23"],["3LS4_H_TCIH220_1","HEAVY CHAIN OF ANTIBODY FAB FRAGMENT","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"VAL A 130;VAL A 110;SER A 127;GLY A 112;GLY A 158","None","0.89A","3ls4H-4bkmA:undetectable","3ls4H-4bkmA:21.45"],["3OZK_B_T44B128_1","TRANSTHYRETIN","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"ALA A  92;LEU A  90;SER A  87;VAL A 156","None","0.91A","3ozkB-4bkmA:undetectable","3ozkB-4bkmA:16.56"],["4AQ7_A_LEUA902_0","LEUCINE--TRNA LIGASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"MET A 300;LEU A 299;SER A 295;GLU A  42","None","1.12A","4aq7A-4bkmA:undetectable","4aq7A-4bkmA:16.00"],["4KTT_A_SAMA405_0","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"HIS A 162;PRO A 161;ASP A 160;SER A 127","None","1.07A","4kttA-4bkmA:undetectable","4kttA-4bkmA:22.82"],["4L4A_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"THR A 262;LEU A  12;VAL A  15;VAL A  22","None","0.91A","4l4aA-4bkmA:undetectable","4l4aA-4bkmA:20.83"],["4L4D_A_CAMA503_0","CAMPHOR 5-MONOOXYGENASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"THR A 262;LEU A  12;VAL A  15;VAL A 245","None","1.04A","4l4dA-4bkmA:undetectable","4l4dA-4bkmA:20.83"],["4NTX_A_AMRA509_1","ACID-SENSING ION CHANNEL 1;BASIC PHOSPHOLIPASE A2 HOMOLOG TX-BETA","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"GLU A  34;GLU A  67;ASN A  60;ARG A  62","None;None;NO3 A1305 ( 4.4A);NO3 A1305 (-4.8A)","1.19A","4ntxA-4bkmA:undetectable;4ntxC-4bkmA:undetectable","4ntxA-4bkmA:22.27;4ntxC-4bkmA:17.08"],["4ODJ_A_SAMA500_0","S-ADENOSYLMETHIONINE SYNTHASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"HIS A 162;PRO A 161;ASP A 160;SER A 127","None","1.11A","4odjA-4bkmA:undetectable","4odjA-4bkmA:20.71"],["4UDC_A_DEXA1778_2","GLUCOCORTICOID RECEPTOR","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",3,"MET A   1;GLN A 284;TYR A 279","None","1.06A","4udcA-4bkmA:undetectable","4udcA-4bkmA:21.07"],["4WNW_B_RTZB602_1","CYTOCHROME P450 2D6","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"PHE A  77;LEU A  44;GLY A 246;SER A 295;VAL A 293","None","1.11A","4wnwB-4bkmA:undetectable","4wnwB-4bkmA:22.36"],["5A6I_A_TCWA1124_1","TRANSTHYRETIN","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"ALA A  92;LEU A  90;SER A  87;VAL A 156","None","1.04A","5a6iA-4bkmA:undetectable","5a6iA-4bkmA:16.67"],["5BW4_A_SAMA301_0","16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"GLY A 269;ASP A 247;ILE A 253;LEU A 273;LEU A 249","None; MG A1304 (-2.1A);None;None;None","1.09A","5bw4A-4bkmA:undetectable","5bw4A-4bkmA:26.35"],["5TIW_A_OAQA302_0","SULFOTRANSFERASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"MET A 187;ILE A 219;VAL A 156;VAL A 157;LEU A  95","None","1.26A","5tiwA-4bkmA:undetectable","5tiwA-4bkmA:21.63"],["5TUD_A_ERMA2001_1","5-HYDROXYTRYPTAMINE RECEPTOR 2B,SOLUBLE CYTOCHROME B562 CHIMERA","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"LEU A  23;ALA A  40;PHE A  72;PHE A  77;LEU A  68","None","1.10A","5tudA-4bkmA:undetectable","5tudA-4bkmA:22.35"],["5VCV_A_1N1A404_2","MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"VAL A 103;LEU A 181;CYH A 180;ASP A 151","None","1.15A","5vcvA-4bkmA:undetectable","5vcvA-4bkmA:23.43"],["6B52_A_OAQA302_0","SULFOTRANSFERASE","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",5,"MET A 187;ILE A 219;VAL A 156;VAL A 157;LEU A  95","None","1.23A","6b52A-4bkmA:undetectable","6b52A-4bkmA:21.63"],["6B89_A_NOVA403_2","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB;LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"ARG A  97;LEU A  96;ALA A 108;GLN A  98","None","1.02A","6b89B-4bkmA:undetectable","6b89B-4bkmA:15.02"],["6FBN_B_SAMB401_1","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","4bkm","PYRIDOXAL PHOSPHATE PHOSPHATASE, PHOSPHOGLYCOLATE PHOSPHATASE, PYRIDOXAL PHOSPHATE PHOSPHATASE","Mus musculus",4,"HIS A 162;PRO A 161;ASP A 160;SER A 127","None","1.12A","6fbnB-4bkmA:undetectable","6fbnB-4bkmA:22.85"]]