SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4blp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		4 / 6 LEU A 119
MET A  59
THR A  60
LEU A  54
 None
 1.00A 1v54A-4blpA:
undetectable
1v54J-4blpA:
undetectable		 1v54A-4blpA:
20.49
1v54J-4blpA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		5 / 10 LEU A 203
ALA A  86
VAL A 109
ALA A 108
PHE A  99
 None
 1.14A 1xp0A-4blpA:
undetectable		 1xp0A-4blpA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		4 / 6 LEU A 119
MET A  59
THR A  60
LEU A  54
 None
 0.99A 2dyrA-4blpA:
undetectable
2dyrJ-4blpA:
undetectable		 2dyrA-4blpA:
20.49
2dyrJ-4blpA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		4 / 6 LEU A 119
MET A  59
THR A  60
LEU A  54
 None
 1.01A 2dysA-4blpA:
undetectable
2dysJ-4blpA:
undetectable		 2dysA-4blpA:
20.49
2dysJ-4blpA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		4 / 6 LEU A 119
MET A  59
THR A  60
LEU A  54
 None
 1.00A 2eilA-4blpA:
undetectable
2eilJ-4blpA:
undetectable		 2eilA-4blpA:
20.49
2eilJ-4blpA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		5 / 12 ILE A 212
LEU A 253
ILE A 172
PHE A 215
VAL A  70
 None
 1.13A 2ygnA-4blpA:
undetectable		 2ygnA-4blpA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		5 / 12 LEU A  67
VAL A 118
PRO A  74
THR A 223
GLY A 221
 None
 1.33A 4hvcB-4blpA:
undetectable		 4hvcB-4blpA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		5 / 12 VAL A 282
VAL A 277
ALA A 157
LEU A 218
VAL A 219
 None
None
FLC  A1304 ( 4.0A)
None
None
 1.25A 4ib4A-4blpA:
undetectable		 4ib4A-4blpA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		4 / 8 PHE A 111
ASP A  78
SER A  64
SER A  53
 None
 1.11A 4lv9A-4blpA:
undetectable
4lv9B-4blpA:
undetectable		 4lv9A-4blpA:
21.26
4lv9B-4blpA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		4 / 7 PHE A 111
ASP A  78
SER A  64
SER A  53
 None
 1.09A 4lv9A-4blpA:
undetectable
4lv9B-4blpA:
undetectable		 4lv9A-4blpA:
21.26
4lv9B-4blpA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		5 / 9 PRO A  95
VAL A  90
VAL A 199
ALA A 200
ALA A 206
 None
 1.07A 4oqrA-4blpA:
undetectable		 4oqrA-4blpA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		5 / 12 GLY A 147
GLY A 250
LEU A 249
ALA A 255
LEU A 242
 None
 1.01A 5c0oG-4blpA:
undetectable		 5c0oG-4blpA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		5 / 12 VAL A 277
ALA A 255
VAL A 150
LEU A 235
LEU A 201
 None
 1.23A 5hv1A-4blpA:
undetectable		 5hv1A-4blpA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		4 / 6 LEU A 119
MET A  59
THR A  60
LEU A  54
 None
 0.95A 5x1fA-4blpA:
undetectable
5x1fJ-4blpA:
undetectable		 5x1fA-4blpA:
20.49
5x1fJ-4blpA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		4 / 7 LEU A 119
MET A  59
THR A  60
LEU A  54
 None
 0.93A 5xdqA-4blpA:
undetectable
5xdqJ-4blpA:
undetectable		 5xdqA-4blpA:
20.49
5xdqJ-4blpA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		4 / 7 LEU A 119
MET A  59
THR A  60
LEU A  54
 None
 0.92A 5xdqN-4blpA:
undetectable
5xdqW-4blpA:
undetectable		 5xdqN-4blpA:
20.49
5xdqW-4blpA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		5 / 12 ASP A 192
LEU A 193
VAL A 110
LEU A 203
LEU A  89
 None
 1.17A 6b54A-4blpA:
undetectable		 6b54A-4blpA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		5 / 12 VAL A 210
ASP A 169
ALA A 200
LEU A  82
LEU A  89
 None
 1.21A 6ew0F-4blpA:
undetectable		 6ew0F-4blpA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		4 / 7 LEU A 119
MET A  59
THR A  60
LEU A  54
 None
 0.96A 6nmfA-4blpA:
undetectable
6nmfJ-4blpA:
undetectable		 6nmfA-4blpA:
20.49
6nmfJ-4blpA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		4 / 7 LEU A 119
MET A  59
THR A  60
LEU A  54
 None
 0.95A 6nmpA-4blpA:
undetectable
6nmpJ-4blpA:
undetectable		 6nmpA-4blpA:
20.49
6nmpJ-4blpA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 4blp PACKAGING ENZYME P4
(Pseudomonas
phage
phi13) 		5 / 11 LEU A 197
LEU A 252
GLY A 147
ASN A 243
ALA A 204
 None
 1.35A 6r2eF-4blpA:
undetectable		 6r2eF-4blpA:
23.41