SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4blq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4blq P4
(Pseudomonas
phage
phi8) 		5 / 12 LEU A 200
ALA A 234
ILE A 109
LEU A 215
LEU A 173
 None
 1.03A 3adxB-4blqA:
undetectable		 3adxB-4blqA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4blq P4
(Pseudomonas
phage
phi8) 		3 / 3 ASN A 121
HIS A 122
VAL A 273
 None
 0.90A 3elzB-4blqA:
undetectable		 3elzB-4blqA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 4blq P4
(Pseudomonas
phage
phi8) 		5 / 12 LEU A 146
ARG A 144
ALA A 140
ASP A 171
THR A 117
 None
 1.29A 3gwuA-4blqA:
undetectable		 3gwuA-4blqA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 4blq P4
(Pseudomonas
phage
phi8) 		3 / 3 ILE A  48
VAL A 207
ARG A  93
 None
 0.75A 3p73A-4blqA:
undetectable		 3p73A-4blqA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 4blq P4
(Pseudomonas
phage
phi8) 		4 / 8 ALA A 135
LEU A 168
ASP A 166
ASP A 164
 None
 1.04A 3qj7A-4blqA:
undetectable
3qj7D-4blqA:
undetectable		 3qj7A-4blqA:
19.54
3qj7D-4blqA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4blq P4
(Pseudomonas
phage
phi8) 		4 / 8 ASP A 171
ASN A 121
ARG A 280
GLY A 114
 None
 1.02A 4af0A-4blqA:
undetectable		 4af0A-4blqA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 4blq P4
(Pseudomonas
phage
phi8) 		5 / 12 GLY A  81
ASP A  78
MET A 196
GLN A 192
VAL A  53
 None
 0.98A 4fr0A-4blqA:
undetectable		 4fr0A-4blqA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 4blq P4
(Pseudomonas
phage
phi8) 		3 / 3 LEU A 132
MET A 209
TYR A 123
 None
 0.80A 4p6xG-4blqA:
undetectable		 4p6xG-4blqA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 4blq P4
(Pseudomonas
phage
phi8) 		5 / 12 VAL A  21
LEU A 173
ALA A 156
THR A 214
ARG A 174
 None
 1.03A 5hnzB-4blqA:
undetectable		 5hnzB-4blqA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 4blq P4
(Pseudomonas
phage
phi8) 		4 / 5 ILE A  48
LEU A  59
GLY A  60
PHE A  61
 None
 0.95A 5kmdC-4blqA:
undetectable
5kmdD-4blqA:
undetectable		 5kmdC-4blqA:
22.47
5kmdD-4blqA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 4blq P4
(Pseudomonas
phage
phi8) 		4 / 5 ASN A 183
ASP A 219
SER A 218
ARG A 174
 None
 1.15A 5w4zA-4blqA:
undetectable		 5w4zA-4blqA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4blq P4
(Pseudomonas
phage
phi8) 		4 / 6 LEU A 173
VAL A 176
LEU A 180
VAL A 150
 None
 0.79A 5x7zA-4blqA:
undetectable		 5x7zA-4blqA:
22.89