SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bm1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		3 / 3 PHE A 193
LEU A 173
SER A 237
 HEM  A 500 (-4.7A)
HEM  A 500 (-4.0A)
HEM  A 500 (-2.7A)
 0.88A 1e7aA-4bm1A:
undetectable		 1e7aA-4bm1A:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 5 PHE A  63
ILE A  78
PRO A 139
GLU A  79
 None
None
None
CA  A 401 ( 4.5A)
 1.49A 1oniG-4bm1A:
undetectable
1oniH-4bm1A:
undetectable		 1oniG-4bm1A:
17.86
1oniH-4bm1A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		5 / 12 LEU A  29
SER A  76
MET A  73
PHE A 109
ILE A  98
 None
 1.40A 1xosA-4bm1A:
undetectable		 1xosA-4bm1A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		5 / 12 ARG A 133
ALA A  14
ASP A  13
VAL A 288
ILE A 283
 None
None
None
None
SO4  A1347 (-4.3A)
 0.93A 2avsB-4bm1A:
undetectable		 2avsB-4bm1A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 5 ASP A  69
SER A  71
LEU A 144
GLY A  52
 CA  A 401 (-3.1A)
CA  A 401 (-2.4A)
None
CA  A 401 ( 4.9A)
 1.05A 2j2pA-4bm1A:
undetectable
2j2pB-4bm1A:
undetectable		 2j2pA-4bm1A:
21.01
2j2pB-4bm1A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 7 THR A 196
PRO A 197
VAL A 178
SER A 177
 CA  A 402 (-3.6A)
None
None
CA  A 402 (-2.4A)
 0.98A 2v2gA-4bm1A:
undetectable
2v2gB-4bm1A:
undetectable		 2v2gA-4bm1A:
22.09
2v2gB-4bm1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 7 THR A 196
PRO A 197
VAL A 178
SER A 177
 CA  A 402 (-3.6A)
None
None
CA  A 402 (-2.4A)
 0.96A 2v2gA-4bm1A:
undetectable
2v2gB-4bm1A:
undetectable		 2v2gA-4bm1A:
22.09
2v2gB-4bm1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 7 THR A 196
PRO A 197
VAL A 178
SER A 177
 CA  A 402 (-3.6A)
None
None
CA  A 402 (-2.4A)
 0.97A 2v2gC-4bm1A:
undetectable
2v2gD-4bm1A:
undetectable		 2v2gC-4bm1A:
22.09
2v2gD-4bm1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 7 THR A 196
PRO A 197
VAL A 178
SER A 177
 CA  A 402 (-3.6A)
None
None
CA  A 402 (-2.4A)
 0.99A 2v2gC-4bm1A:
undetectable
2v2gD-4bm1A:
undetectable		 2v2gC-4bm1A:
22.09
2v2gD-4bm1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 8 THR A 196
PRO A 197
VAL A 178
SER A 177
 CA  A 402 (-3.6A)
None
None
CA  A 402 (-2.4A)
 0.96A 2v32A-4bm1A:
undetectable
2v32B-4bm1A:
undetectable		 2v32A-4bm1A:
22.09
2v32B-4bm1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 8 THR A 196
PRO A 197
VAL A 178
ALA A 122
 CA  A 402 (-3.6A)
None
None
None
 1.00A 2v32A-4bm1A:
undetectable
2v32B-4bm1A:
undetectable		 2v32A-4bm1A:
22.09
2v32B-4bm1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 8 THR A 196
PRO A 197
VAL A 178
SER A 177
 CA  A 402 (-3.6A)
None
None
CA  A 402 (-2.4A)
 0.97A 2v32A-4bm1A:
undetectable
2v32B-4bm1A:
undetectable		 2v32A-4bm1A:
22.09
2v32B-4bm1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 8 THR A 196
PRO A 197
VAL A 178
SER A 177
 CA  A 402 (-3.6A)
None
None
CA  A 402 (-2.4A)
 0.98A 2v32C-4bm1A:
undetectable
2v32D-4bm1A:
undetectable		 2v32C-4bm1A:
22.09
2v32D-4bm1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 8 THR A 196
PRO A 197
VAL A 178
ALA A 122
 CA  A 402 (-3.6A)
None
None
None
 0.91A 2v41G-4bm1A:
undetectable
2v41H-4bm1A:
undetectable		 2v41G-4bm1A:
22.09
2v41H-4bm1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		3 / 3 SER A  71
GLY A  67
GLY A  65
 CA  A 401 (-2.4A)
CA  A 401 (-4.3A)
None
 0.56A 3bogA-4bm1A:
undetectable
3bogC-4bm1A:
undetectable		 3bogA-4bm1A:
undetectable
3bogC-4bm1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		5 / 12 HIS A 191
GLY A 231
GLY A 217
ALA A 189
ASP A 182
 None
CIT  A1349 (-3.6A)
None
None
HEM  A 500 (-4.7A)
 1.12A 3keeD-4bm1A:
undetectable		 3keeD-4bm1A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		5 / 12 LEU A 301
LEU A 210
ILE A 310
ASP A 201
SER A 177
 None
None
None
CA  A 402 (-3.0A)
CA  A 402 (-2.4A)
 1.10A 3ko0K-4bm1A:
undetectable
3ko0L-4bm1A:
undetectable
3ko0M-4bm1A:
undetectable
3ko0N-4bm1A:
undetectable		 3ko0K-4bm1A:
16.56
3ko0L-4bm1A:
16.56
3ko0M-4bm1A:
16.56
3ko0N-4bm1A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		5 / 12 LEU A  29
VAL A 116
GLY A 117
PHE A 112
GLU A  38
 None
 1.26A 3medA-4bm1A:
undetectable
3medB-4bm1A:
undetectable		 3medA-4bm1A:
19.40
3medB-4bm1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 5 VAL A 169
LEU A 172
ILE A  51
ALA A 162
 HEM  A 500 ( 4.7A)
HEM  A 500 (-3.3A)
None
None
 0.99A 3n8yB-4bm1A:
undetectable		 3n8yB-4bm1A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		5 / 12 ALA A 115
ARG A 126
SER A 286
ARG A 133
ALA A 270
 None
 1.20A 3qxvE-4bm1A:
undetectable		 3qxvE-4bm1A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		3 / 3 PHE A 233
SER A 227
GLN A 224
 None
 0.85A 3smtA-4bm1A:
undetectable		 3smtA-4bm1A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		5 / 12 ILE A  72
GLY A  87
THR A  80
ASP A 182
LEU A 235
 None
None
None
HEM  A 500 (-4.7A)
HEM  A 500 (-3.8A)
 1.16A 3v8vA-4bm1A:
undetectable		 3v8vA-4bm1A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		5 / 12 PRO A 320
LEU A 322
ILE A 310
ILE A 255
PHE A 204
 None
 1.24A 4a79A-4bm1A:
undetectable		 4a79A-4bm1A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		5 / 12 PRO A 320
LEU A 322
ILE A 310
ILE A 255
PHE A 204
 None
 1.27A 4a79B-4bm1A:
undetectable		 4a79B-4bm1A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		3 / 3 ASP A  23
LEU A  22
PHE A  19
 None
 0.42A 4pthA-4bm1A:
undetectable		 4pthA-4bm1A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		5 / 12 SER A  54
PRO A  55
GLY A  52
GLY A  67
GLY A  66
 None
None
CA  A 401 ( 4.9A)
CA  A 401 (-4.3A)
None
 1.10A 4yvgA-4bm1A:
undetectable		 4yvgA-4bm1A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 6 LEU A 220
SER A 219
ASP A 218
HIS A 191
 None
 1.22A 5om3A-4bm1A:
undetectable
5om3B-4bm1A:
undetectable		 5om3A-4bm1A:
13.73
5om3B-4bm1A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		5 / 11 PHE A  53
GLY A  52
GLY A  70
GLN A 277
THR A  46
 None
CA  A 401 ( 4.9A)
None
None
HEM  A 500 ( 4.8A)
 1.29A 5x19G-4bm1A:
undetectable
5x19N-4bm1A:
0.7
5x19O-4bm1A:
undetectable		 5x19G-4bm1A:
14.90
5x19N-4bm1A:
20.42
5x19O-4bm1A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		6 / 12 GLY A  66
GLY A 276
LEU A  57
GLY A  64
GLY A  65
PRO A 141
 None
 1.33A 5zhmB-4bm1A:
undetectable		 5zhmB-4bm1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4bm1 MANGANESE PEROXIDASE
4
(Pleurotus
ostreatus) 		4 / 7 ALA A 113
GLY A 114
LEU A  43
GLY A  33
 None
None
HEM  A 500 ( 3.3A)
None
 0.49A 6nm4A-4bm1A:
undetectable		 6nm4A-4bm1A:
18.86