SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bma'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		4 / 6 ASN A  75
ALA A  42
GLY A  43
TYR A  39
 None
 1.13A 1c8lA-4bmaA:
undetectable		 1c8lA-4bmaA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		4 / 8 SER A 485
ILE A 484
LEU A 491
GLU A 489
 None
 0.82A 1eupA-4bmaA:
undetectable		 1eupA-4bmaA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 11 VAL A 480
GLY A 467
ILE A 468
ALA A 503
ILE A 505
 None
 0.95A 2idwA-4bmaA:
undetectable		 2idwA-4bmaA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 12 ALA A 286
ASP A 287
GLY A 120
VAL A 185
ILE A 186
 None
 1.08A 2o4lA-4bmaA:
undetectable		 2o4lA-4bmaA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_C_GLYC73_0
(NONSTRUCTURAL
PROTEIN 1)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		4 / 4 ASP A 431
ASP A 453
SER A 456
ARG A 460
 None
 1.42A 2z0aC-4bmaA:
0.0		 2z0aC-4bmaA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 10 VAL A 480
GLY A 467
ILE A 468
ALA A 503
ILE A 505
 None
 0.96A 3ekpB-4bmaA:
undetectable		 3ekpB-4bmaA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 9 VAL A 480
GLY A 467
ILE A 468
ALA A 503
ILE A 505
 None
 1.06A 3ektB-4bmaA:
undetectable		 3ektB-4bmaA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 9 VAL A 480
GLY A 467
ILE A 468
ALA A 503
ILE A 505
 None
 0.99A 3el0B-4bmaA:
undetectable		 3el0B-4bmaA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		4 / 6 TYR A 361
GLY A 250
GLU A 407
GLU A 329
 None
 1.04A 3fpjA-4bmaA:
undetectable		 3fpjA-4bmaA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		4 / 5 ARG A 460
LEU A 106
ARG A 429
ILE A 356
 None
 1.26A 3ln1D-4bmaA:
undetectable		 3ln1D-4bmaA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		4 / 7 ILE A 252
LYS A 364
PHE A 365
LYS A 421
 None
 1.24A 3sj0X-4bmaA:
undetectable		 3sj0X-4bmaA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		4 / 7 ILE A 186
HIS A 274
ALA A 286
ALA A 176
 None
 0.82A 4g77A-4bmaA:
undetectable		 4g77A-4bmaA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 12 GLY A 251
GLN A 408
VAL A 413
HIS A 359
THR A 275
 None
 1.25A 4ojbA-4bmaA:
undetectable		 4ojbA-4bmaA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 12 GLY A 251
GLN A 408
VAL A 413
HIS A 359
THR A 275
 None
 1.27A 4okwA-4bmaA:
undetectable		 4okwA-4bmaA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 12 GLY A 251
GLN A 408
VAL A 413
HIS A 359
THR A 275
 None
 1.26A 4okxA-4bmaA:
undetectable		 4okxA-4bmaA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 12 GLY A 251
GLN A 408
VAL A 413
HIS A 359
THR A 275
 None
 1.27A 4olmA-4bmaA:
undetectable		 4olmA-4bmaA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 11 SER A 456
GLU A 444
GLU A 313
ASP A 446
ASP A 445
 None
 1.35A 4qb9F-4bmaA:
undetectable		 4qb9F-4bmaA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 12 ALA A 302
SER A 368
LEU A 123
ILE A 270
MET A 265
 None
 1.15A 5hv1A-4bmaA:
undetectable		 5hv1A-4bmaA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		3 / 3 SER A 362
TYR A 361
TYR A 360
 None
 0.79A 5lakA-4bmaA:
undetectable
5lakI-4bmaA:
undetectable		 5lakA-4bmaA:
18.98
5lakI-4bmaA:
0.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		3 / 3 SER A 362
TYR A 361
TYR A 360
 None
 0.71A 5lakC-4bmaA:
undetectable
5lakJ-4bmaA:
undetectable		 5lakC-4bmaA:
18.98
5lakJ-4bmaA:
0.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Aspergillus
fumigatus) 		5 / 12 LEU A 235
ALA A 243
VAL A 244
ALA A  42
PHE A  69
 None
 1.10A 5n5dB-4bmaA:
2.3		 5n5dB-4bmaA:
20.33