SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 4bmh ACETYLTRANSFERASE
(Streptomyces
sviceus) 		6 / 11 CYH A  75
ILE A  74
ALA A 121
VAL A 113
ARG A  64
VAL A 104
 None
 1.50A 1n4hA-4bmhA:
undetectable		 1n4hA-4bmhA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 4bmh ACETYLTRANSFERASE
(Streptomyces
sviceus) 		4 / 8 TYR A 138
PHE A 134
ALA A 100
HIS A 187
 None
 1.17A 1x8vA-4bmhA:
undetectable		 1x8vA-4bmhA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 4bmh ACETYLTRANSFERASE
(Streptomyces
sviceus) 		5 / 12 THR A  78
LEU A 190
ALA A 100
MET A 204
THR A 206
 None
 1.08A 3czhB-4bmhA:
undetectable		 3czhB-4bmhA:
20.20