SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bmv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 11 LEU A  33
ALA A  18
GLU A  51
ALA A  25
VAL A  56
 None
 1.21A 1ictA-4bmvA:
undetectable
1ictC-4bmvA:
undetectable		 1ictA-4bmvA:
20.23
1ictC-4bmvA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		3 / 3 ALA A 184
VAL A 204
TRP A 191
 None
None
NAP  A 300 (-4.0A)
 0.92A 1jnoA-4bmvA:
undetectable		 1jnoA-4bmvA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		3 / 3 ALA A 184
VAL A 204
TRP A 191
 None
None
NAP  A 300 (-4.0A)
 0.92A 1jnoB-4bmvA:
undetectable		 1jnoB-4bmvA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		3 / 3 ALA A 184
VAL A 204
TRP A 191
 None
None
NAP  A 300 (-4.0A)
 0.94A 1jo4A-4bmvA:
undetectable		 1jo4A-4bmvA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		3 / 3 ALA A 184
VAL A 204
TRP A 191
 None
None
NAP  A 300 (-4.0A)
 0.94A 1jo4B-4bmvA:
undetectable		 1jo4B-4bmvA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		3 / 3 ALA A 184
VAL A 204
TRP A 191
 None
None
NAP  A 300 (-4.0A)
 0.88A 1magA-4bmvA:
undetectable		 1magA-4bmvA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		3 / 3 ALA A 184
VAL A 204
TRP A 191
 None
None
NAP  A 300 (-4.0A)
 0.88A 1magB-4bmvA:
undetectable		 1magB-4bmvA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		3 / 3 ALA A 184
VAL A 204
TRP A 191
 None
None
NAP  A 300 (-4.0A)
 0.91A 1ng8A-4bmvA:
undetectable		 1ng8A-4bmvA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		3 / 3 ALA A 184
VAL A 204
TRP A 191
 None
None
NAP  A 300 (-4.0A)
 0.91A 1ng8B-4bmvA:
undetectable		 1ng8B-4bmvA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		4 / 8 ALA A 194
TRP A 191
ILE A 190
TYR A 153
 None
NAP  A 300 (-4.0A)
NAP  A 300 (-3.7A)
NAP  A 300 (-4.5A)
 0.86A 2zm8A-4bmvA:
undetectable		 2zm8A-4bmvA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		4 / 8 ALA A 194
TRP A 191
ILE A 190
TYR A 153
 None
NAP  A 300 (-4.0A)
NAP  A 300 (-3.7A)
NAP  A 300 (-4.5A)
 0.86A 2zmaA-4bmvA:
undetectable		 2zmaA-4bmvA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		4 / 7 GLU A  22
ARG A  47
GLU A  51
SER A  52
 None
 1.04A 2zt7A-4bmvA:
undetectable		 2zt7A-4bmvA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 10 ILE A   9
ASN A  88
ALA A  89
VAL A  32
LEU A  41
 None
NAP  A 300 (-3.4A)
NAP  A 300 ( 3.9A)
None
None
 1.29A 3ay0A-4bmvA:
6.6		 3ay0A-4bmvA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 10 ARG A  26
ALA A  25
LEU A  33
LEU A  31
VAL A  54
 None
 1.21A 3o02A-4bmvA:
undetectable
3o02B-4bmvA:
undetectable		 3o02A-4bmvA:
21.81
3o02B-4bmvA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 12 ALA A  61
GLN A  60
LEU A  41
ILE A  82
LEU A 119
 None
 0.97A 3oapA-4bmvA:
undetectable		 3oapA-4bmvA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 12 LEU A  41
ALA A  21
GLY A  17
SER A  13
LEU A  48
 None
None
None
NAP  A 300 (-2.8A)
None
 1.19A 3ou7A-4bmvA:
5.4		 3ou7A-4bmvA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 12 LEU A  41
ALA A  21
GLY A  17
SER A  13
LEU A  48
 None
None
None
NAP  A 300 (-2.8A)
None
 1.23A 3ou7D-4bmvA:
5.9		 3ou7D-4bmvA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 12 LEU A 215
GLY A  17
SER A  14
ARG A  40
ILE A  16
 None
None
NAP  A 300 (-2.6A)
None
NAP  A 300 (-4.0A)
 1.27A 4djeA-4bmvA:
2.5		 4djeA-4bmvA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 12 VAL A 181
GLY A  17
GLY A  15
ILE A 138
ILE A  86
 None
None
NAP  A 300 (-3.6A)
NAP  A 300 (-4.6A)
None
 1.02A 4iv0A-4bmvA:
6.0		 4iv0A-4bmvA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 10 GLU A 170
ILE A 176
VAL A 178
ALA A 120
ILE A 135
 None
 0.98A 4lbgA-4bmvA:
6.0		 4lbgA-4bmvA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 9 GLU A 170
ILE A 176
VAL A 178
ALA A 120
ILE A 135
 None
 1.03A 4lbgB-4bmvA:
6.7		 4lbgB-4bmvA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 12 VAL A 181
GLY A  17
GLY A  15
ILE A 138
ILE A  86
 None
None
NAP  A 300 (-3.6A)
NAP  A 300 (-4.6A)
None
 0.98A 4mwzB-4bmvA:
5.9		 4mwzB-4bmvA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 12 VAL A 136
LEU A  85
ILE A  86
VAL A  72
LEU A  63
 None
None
None
None
NAP  A 300 (-4.0A)
 0.97A 4y8wA-4bmvA:
undetectable		 4y8wA-4bmvA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 12 VAL A 136
LEU A  85
ILE A  86
VAL A  72
LEU A  63
 None
None
None
None
NAP  A 300 (-4.0A)
 0.92A 4y8wB-4bmvA:
undetectable		 4y8wB-4bmvA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		4 / 6 PHE A 127
LEU A 167
ASN A 168
ARG A 126
 None
 1.43A 4yv5B-4bmvA:
undetectable		 4yv5B-4bmvA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 12 ALA A  12
GLY A  17
GLU A 206
LEU A 210
GLU A 209
 None
 1.27A 5nwuA-4bmvA:
undetectable		 5nwuA-4bmvA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		4 / 6 GLU A  73
ARG A  77
ALA A 121
LEU A 119
 None
 1.03A 5phhA-4bmvA:
undetectable		 5phhA-4bmvA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4bmv SHORT-CHAIN
DEHYDROGENASE
(Sphingobium
yanoikuyae) 		5 / 12 ALA A  61
GLN A  60
LEU A  41
ILE A  82
LEU A 119
 None
 0.99A 6a5yD-4bmvA:
undetectable		 6a5yD-4bmvA:
14.72