SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bmw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MG0_Y_BO2Y1403_1 (PROTEASOME COMPONENT PRE2 PROTEASOME COMPONENT C5)	4bmw	EXTRACELLULAR HAEM-BINDING PROTEIN (Streptomyces reticuli)	6 / 12	ALA A 151 ALA A 149 ALA A 152 VAL A 122 ALA A 84 GLY A 133	None	1.48A	3mg0Y-4bmwA: undetectable 3mg0Z-4bmwA: undetectable	3mg0Y-4bmwA: 21.72 3mg0Z-4bmwA: 20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8Y_B_SALB900_1 (PROSTAGLANDIN G/H SYNTHASE 1)	4bmw	EXTRACELLULAR HAEM-BINDING PROTEIN (Streptomyces reticuli)	4 / 5	VAL A 153 LEU A 154 ILE A 132 ALA A 38	None	0.98A	3n8yB-4bmwA: undetectable	3n8yB-4bmwA: 14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1K_B_LOCB502_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	4bmw	EXTRACELLULAR HAEM-BINDING PROTEIN (Streptomyces reticuli)	5 / 12	LEU A 31 LEU A 29 ALA A 33 LYS A 36 ALA A 130	None	1.07A	4x1kA-4bmwA: undetectable 4x1kB-4bmwA: undetectable	4x1kA-4bmwA: 17.19 4x1kB-4bmwA: 16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K50_A_ACTA1403_0 (L-THREONINE 3-DEHYDROGENASE)	4bmw	EXTRACELLULAR HAEM-BINDING PROTEIN (Streptomyces reticuli)	4 / 5	SER A 53 VAL A 52 GLY A 136 ALA A 135	None	1.02A	5k50A-4bmwA: undetectable	5k50A-4bmwA: 21.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3MG0_Y_BO2Y1403_1","PROTEASOME COMPONENT PRE2;PROTEASOME COMPONENT C5","4bmw","EXTRACELLULAR HAEM-BINDING PROTEIN","Streptomyces reticuli",6,"ALA A 151;ALA A 149;ALA A 152;VAL A 122;ALA A  84;GLY A 133","None","1.48A","3mg0Y-4bmwA:undetectable;3mg0Z-4bmwA:undetectable","3mg0Y-4bmwA:21.72;3mg0Z-4bmwA:20.54"],["3N8Y_B_SALB900_1","PROSTAGLANDIN G\/H SYNTHASE 1","4bmw","EXTRACELLULAR HAEM-BINDING PROTEIN","Streptomyces reticuli",4,"VAL A 153;LEU A 154;ILE A 132;ALA A  38","None","0.98A","3n8yB-4bmwA:undetectable","3n8yB-4bmwA:14.34"],["4X1K_B_LOCB502_1","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","4bmw","EXTRACELLULAR HAEM-BINDING PROTEIN","Streptomyces reticuli",5,"LEU A  31;LEU A  29;ALA A  33;LYS A  36;ALA A 130","None","1.07A","4x1kA-4bmwA:undetectable;4x1kB-4bmwA:undetectable","4x1kA-4bmwA:17.19;4x1kB-4bmwA:16.95"],["5K50_A_ACTA1403_0","L-THREONINE 3-DEHYDROGENASE","4bmw","EXTRACELLULAR HAEM-BINDING PROTEIN","Streptomyces reticuli",4,"SER A  53;VAL A  52;GLY A 136;ALA A 135","None","1.02A","5k50A-4bmwA:undetectable","5k50A-4bmwA:21.43"]]