SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bn2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		4 / 6 LEU A 247
VAL A  80
VAL A 121
SER A 125
 None
 1.06A 1e7aB-4bn2A:
undetectable		 1e7aB-4bn2A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		4 / 7 TYR A 301
THR A  90
THR A 320
VAL A 284
 None
 1.04A 1tv8A-4bn2A:
undetectable		 1tv8A-4bn2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		3 / 3 GLN A 159
ILE A 160
TYR A 161
 None
 0.74A 1vifA-4bn2A:
undetectable		 1vifA-4bn2A:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		5 / 12 LEU A 278
ILE A 322
ILE A  13
ILE A 285
TYR A  94
 None
 1.39A 2efjA-4bn2A:
undetectable		 2efjA-4bn2A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		4 / 8 TYR A 301
THR A  90
THR A 320
VAL A 284
 None
 1.04A 2fb2A-4bn2A:
undetectable		 2fb2A-4bn2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		4 / 7 TYR A 301
THR A  90
THR A 320
VAL A 284
 None
 1.07A 2fb2B-4bn2A:
undetectable		 2fb2B-4bn2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		5 / 12 PHE A  72
PHE A 146
ILE A 230
ILE A 228
CYH A 148
 None
 1.09A 2ft9A-4bn2A:
undetectable		 2ft9A-4bn2A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		5 / 12 LEU A 246
ASN A  88
LEU A 247
VAL A 225
LEU A 309
 None
 1.19A 2q7kA-4bn2A:
undetectable		 2q7kA-4bn2A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		5 / 12 LEU A 246
ASN A  88
LEU A 247
VAL A 250
LEU A 310
 None
 1.28A 2q7kA-4bn2A:
undetectable		 2q7kA-4bn2A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		5 / 12 LEU A 246
ASN A  88
LEU A 247
GLY A  89
VAL A 250
 None
 1.28A 2q7lA-4bn2A:
undetectable		 2q7lA-4bn2A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		4 / 6 ILE A 153
PRO A 123
SER A 125
MET A 105
 None
 1.41A 2qd3B-4bn2A:
undetectable		 2qd3B-4bn2A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		5 / 12 ILE A 153
LEU A 163
LEU A 164
THR A  90
THR A 227
 None
 1.21A 3dcjA-4bn2A:
undetectable
3dcjB-4bn2A:
undetectable		 3dcjA-4bn2A:
22.41
3dcjB-4bn2A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		5 / 12 ILE A 323
ALA A 321
ALA A 346
LEU A 281
ILE A 285
 None
 1.08A 3gwsX-4bn2A:
undetectable		 3gwsX-4bn2A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		5 / 12 LEU A 173
ARG A 311
VAL A 225
HIS A 223
LEU A 252
 None
 1.44A 3vt7A-4bn2A:
undetectable		 3vt7A-4bn2A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		4 / 7 TRP A 205
THR A 102
ARG A 208
SER A 219
 None
MG  A 601 ( 3.5A)
MG  A 601 ( 4.8A)
None
 1.19A 4o4dA-4bn2A:
undetectable		 4o4dA-4bn2A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		5 / 9 ALA A 343
ALA A 346
VAL A 326
GLY A  95
ALA A 324
 None
 1.17A 4qvnY-4bn2A:
undetectable
4qvnZ-4bn2A:
undetectable		 4qvnY-4bn2A:
21.68
4qvnZ-4bn2A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		5 / 12 GLY A 203
GLY A 204
ASN A 207
MET A 106
ALA A 224
 None
 1.11A 4ubeA-4bn2A:
undetectable		 4ubeA-4bn2A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		4 / 6 ARG A 331
LEU A  35
PRO A  22
SER A  26
 None
 1.27A 5syjA-4bn2A:
undetectable		 5syjA-4bn2A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		4 / 6 ARG A 331
LEU A  35
PRO A  22
SER A  26
 None
 1.27A 5syjB-4bn2A:
undetectable		 5syjB-4bn2A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4bn2 KINESIN-LIKE PROTEIN
KIF15
(Homo
sapiens) 		4 / 8 HIS A 223
VAL A 225
VAL A 250
LEU A 310
 None
 0.81A 5tt3F-4bn2A:
undetectable		 5tt3F-4bn2A:
19.13