SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4bn7 COPPER INDUCED
NITROREDUCTASE D
(Lactococcus
lactis) 		3 / 3 TRP A 171
VAL A 137
ARG A  10
 None
None
FMN  A 504 (-3.0A)
 0.83A 3b0wA-4bn7A:
undetectable		 3b0wA-4bn7A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4bn7 COPPER INDUCED
NITROREDUCTASE D
(Lactococcus
lactis) 		3 / 3 ASP A  57
LYS A  58
ASP A  61
 None
 0.86A 4a7tA-4bn7A:
undetectable		 4a7tA-4bn7A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 4bn7 COPPER INDUCED
NITROREDUCTASE D
(Lactococcus
lactis) 		5 / 9 ALA A 142
GLY A  97
PHE A 179
SER A 181
GLY A 147
 None
 1.19A 4mm5A-4bn7A:
undetectable		 4mm5A-4bn7A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 4bn7 COPPER INDUCED
NITROREDUCTASE D
(Lactococcus
lactis) 		5 / 9 ALA A 142
GLY A  97
PHE A 179
SER A 181
GLY A 147
 None
 1.25A 4mmbA-4bn7A:
undetectable		 4mmbA-4bn7A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 4bn7 COPPER INDUCED
NITROREDUCTASE D
(Lactococcus
lactis) 		5 / 9 ALA A 142
GLY A  97
PHE A 179
SER A 181
GLY A 147
 None
 1.17A 4mmeA-4bn7A:
undetectable		 4mmeA-4bn7A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4bn7 COPPER INDUCED
NITROREDUCTASE D
(Lactococcus
lactis) 		5 / 12 SER A 134
LEU A  16
LEU A 177
ALA A 148
LEU A 146
 None
 1.19A 4x1kA-4bn7A:
undetectable
4x1kB-4bn7A:
undetectable		 4x1kA-4bn7A:
19.02
4x1kB-4bn7A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4bn7 COPPER INDUCED
NITROREDUCTASE D
(Lactococcus
lactis) 		5 / 5 PHE A 179
ILE A  50
GLY A  97
ILE A  30
LEU A  51
 None
 1.49A 5dzkB-4bn7A:
undetectable
5dzkI-4bn7A:
undetectable
5dzkW-4bn7A:
undetectable		 5dzkB-4bn7A:
22.27
5dzkI-4bn7A:
24.00
5dzkW-4bn7A:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 4bn7 COPPER INDUCED
NITROREDUCTASE D
(Lactococcus
lactis) 		4 / 6 LEU A 141
ALA A 148
LEU A 146
SER A 181
 None
 1.12A 5l4iB-4bn7A:
undetectable		 5l4iB-4bn7A:
19.90