SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bnd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 4bnd ALPHA-PHOSPHOGLUCOMU
TASE
(Lactococcus
lactis) 		4 / 5 LEU B 200
ILE B   4
LEU B   5
SER B   6
 None
 0.83A 2byoA-4bndB:
undetectable		 2byoA-4bndB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 4bnd ALPHA-PHOSPHOGLUCOMU
TASE
(Lactococcus
lactis) 		4 / 7 PHE B  87
PHE B  68
ALA B  77
LEU B 200
 None
 0.85A 3t3sC-4bndB:
undetectable		 3t3sC-4bndB:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4bnd ALPHA-PHOSPHOGLUCOMU
TASE
(Lactococcus
lactis) 		4 / 7 ILE B 242
ASP B 212
GLY B 211
PHE B 210
 None
 0.87A 4iqqB-4bndB:
undetectable		 4iqqB-4bndB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4bnd ALPHA-PHOSPHOGLUCOMU
TASE
(Lactococcus
lactis) 		4 / 7 ILE B 242
ASP B 212
GLY B 211
PHE B 210
 None
 0.81A 4iqqC-4bndB:
undetectable		 4iqqC-4bndB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 4bnd ALPHA-PHOSPHOGLUCOMU
TASE
(Lactococcus
lactis) 		4 / 6 LEU B  62
ASN B  61
LEU B  67
ILE B  36
 None
 1.15A 4okxA-4bndB:
undetectable		 4okxA-4bndB:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FEP_A_SAMA407_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 4bnd ALPHA-PHOSPHOGLUCOMU
TASE
(Lactococcus
lactis) 		5 / 12 GLN B  74
SER B 130
ARG B 128
ILE B  50
TYR B  76
 None
None
GOL  B1256 (-3.5A)
None
None
 1.25A 5fepA-4bndB:
undetectable		 5fepA-4bndB:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FES_A_SAMA408_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 4bnd ALPHA-PHOSPHOGLUCOMU
TASE
(Lactococcus
lactis) 		5 / 12 GLN B  74
SER B 130
ARG B 128
ILE B  50
TYR B  76
 None
None
GOL  B1256 (-3.5A)
None
None
 1.25A 5fesA-4bndB:
undetectable		 5fesA-4bndB:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 4bnd ALPHA-PHOSPHOGLUCOMU
TASE
(Lactococcus
lactis) 		5 / 12 LEU B  13
ASP B 220
GLY B 211
ASN B  11
ALA B 240
 None
None
None
None
GOL  B1253 ( 2.6A)
 1.36A 5kbwB-4bndB:
undetectable		 5kbwB-4bndB:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 4bnd ALPHA-PHOSPHOGLUCOMU
TASE
(Lactococcus
lactis) 		5 / 12 LEU B  13
ASP B 220
GLY B 211
ASN B  11
TYR B 209
 None
 1.32A 5kbwB-4bndB:
undetectable		 5kbwB-4bndB:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 4bnd ALPHA-PHOSPHOGLUCOMU
TASE
(Lactococcus
lactis) 		4 / 5 ARG B 128
ALA B  70
GLN B  51
ILE B   9
 GOL  B1256 (-3.5A)
None
None
None
 1.21A 6g9bA-4bndB:
undetectable
6g9bB-4bndB:
undetectable		 6g9bA-4bndB:
15.98
6g9bB-4bndB:
14.23