SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.94A 1t3rA-4bo6A:
undetectable		 1t3rA-4bo6A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.96A 1t7iA-4bo6A:
undetectable		 1t7iA-4bo6A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.88A 1t7jA-4bo6A:
undetectable		 1t7jA-4bo6A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.95A 2idwB-4bo6A:
undetectable		 2idwB-4bo6A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  21
ALA A  20
GLY A  16
ILE A 218
GLY A  12
 None
 0.83A 2qe6A-4bo6A:
5.9		 2qe6A-4bo6A:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  21
ALA A  20
GLY A  16
ILE A 218
GLY A  12
 None
 0.88A 2qe6B-4bo6A:
6.6		 2qe6B-4bo6A:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.98A 3ektA-4bo6A:
undetectable		 3ektA-4bo6A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		4 / 7 GLY A  34
GLY A  58
THR A  48
ALA A  13
 None
 0.88A 3fpjB-4bo6A:
7.1		 3fpjB-4bo6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 1.03A 3gguB-4bo6A:
undetectable		 3gguB-4bo6A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.93A 3lzvA-4bo6A:
undetectable		 3lzvA-4bo6A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.96A 3oy4B-4bo6A:
undetectable		 3oy4B-4bo6A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  25
GLY A 223
ILE A 139
VAL A 182
 None
 0.80A 3wriA-4bo6A:
undetectable		 3wriA-4bo6A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  25
GLY A 223
ILE A 139
VAL A 182
 None
 0.81A 3wriB-4bo6A:
undetectable		 3wriB-4bo6A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  25
GLY A 223
ILE A 139
VAL A 182
 None
 0.88A 3wrkA-4bo6A:
undetectable		 3wrkA-4bo6A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 8 LEU A 204
ILE A 207
ASN A 241
GLY A 185
ILE A 187
 None
 0.93A 3wxoA-4bo6A:
undetectable		 3wxoA-4bo6A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 11 ILE A  21
ILE A  17
GLY A  16
VAL A 240
GLY A 213
 None
 0.99A 4ac9B-4bo6A:
6.8
4ac9C-4bo6A:
6.7		 4ac9B-4bo6A:
22.93
4ac9C-4bo6A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.94A 4dqbB-4bo6A:
undetectable		 4dqbB-4bo6A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.97A 4dqcB-4bo6A:
undetectable		 4dqcB-4bo6A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.96A 4dqeB-4bo6A:
undetectable		 4dqeB-4bo6A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.95A 4dqhB-4bo6A:
undetectable		 4dqhB-4bo6A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  30
GLY A 223
ALA A 226
VAL A  10
VAL A  87
 None
 1.08A 4nkvA-4bo6A:
undetectable		 4nkvA-4bo6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  30
GLY A 223
ALA A 226
VAL A  10
VAL A  87
 None
 1.07A 4nkvC-4bo6A:
undetectable		 4nkvC-4bo6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  30
GLY A 223
ALA A 226
VAL A  10
VAL A  87
 None
 1.08A 4nkvD-4bo6A:
undetectable		 4nkvD-4bo6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  30
GLY A 223
ALA A 226
VAL A  10
VAL A  87
 None
 0.99A 4nkxC-4bo6A:
undetectable		 4nkxC-4bo6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  30
GLY A 223
ALA A 226
VAL A  10
VAL A  87
 None
 1.02A 4nkxD-4bo6A:
undetectable		 4nkxD-4bo6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.97A 4q1wA-4bo6A:
undetectable		 4q1wA-4bo6A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.94A 4q1xA-4bo6A:
undetectable		 4q1xA-4bo6A:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.94A 4q1yA-4bo6A:
undetectable		 4q1yA-4bo6A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  12
GLY A  34
LEU A  59
ILE A  21
ALA A  90
 None
 1.14A 4qtuB-4bo6A:
6.3		 4qtuB-4bo6A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 218
ALA A 219
GLY A  18
GLY A 185
VAL A 142
 None
 1.26A 5i71A-4bo6A:
undetectable		 5i71A-4bo6A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 117
GLY A  91
ALA A  90
GLY A  18
ILE A  17
 None
 0.98A 5kr0B-4bo6A:
undetectable		 5kr0B-4bo6A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 4bo6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 161
PRO A 184
ALA A 183
GLU A  24
PHE A 224
 None
 1.15A 5x6yA-4bo6A:
3.4		 5x6yA-4bo6A:
14.57