SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 8 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.73A 2eijN-4bobA:
undetectable
2eijW-4bobA:
undetectable		 2eijN-4bobA:
15.65
2eijW-4bobA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 7 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.72A 2eikA-4bobA:
undetectable
2eikJ-4bobA:
undetectable		 2eikA-4bobA:
15.65
2eikJ-4bobA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 8 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.72A 2eikN-4bobA:
undetectable
2eikW-4bobA:
undetectable		 2eikN-4bobA:
15.65
2eikW-4bobA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 8 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.71A 2eilN-4bobA:
undetectable
2eilW-4bobA:
undetectable		 2eilN-4bobA:
15.65
2eilW-4bobA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 5 THR A  76
SER A  79
ASP A  65
SER A 101
 None
 1.25A 2hdnA-4bobA:
undetectable
2hdnB-4bobA:
undetectable
2hdnD-4bobA:
undetectable		 2hdnA-4bobA:
12.99
2hdnB-4bobA:
18.45
2hdnD-4bobA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 5 SER A 101
THR A  76
SER A  79
ASP A  65
 None
 1.27A 2hdnB-4bobA:
undetectable
2hdnC-4bobA:
undetectable
2hdnD-4bobA:
undetectable		 2hdnB-4bobA:
18.45
2hdnC-4bobA:
12.99
2hdnD-4bobA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 6 THR A  76
SER A  79
ASP A  65
SER A 101
 None
 1.26A 2hdnI-4bobA:
undetectable
2hdnJ-4bobA:
undetectable
2hdnL-4bobA:
undetectable		 2hdnI-4bobA:
12.99
2hdnJ-4bobA:
18.45
2hdnL-4bobA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 6 SER A 101
THR A  76
SER A  79
ASP A  65
 None
 1.25A 2hdnJ-4bobA:
undetectable
2hdnK-4bobA:
undetectable
2hdnL-4bobA:
undetectable		 2hdnJ-4bobA:
18.45
2hdnK-4bobA:
12.99
2hdnL-4bobA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 6 THR A 150
GLU A 152
PHE A 136
ILE A 122
 None
 1.11A 2w98B-4bobA:
undetectable		 2w98B-4bobA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 8 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.78A 3ablN-4bobA:
undetectable
3ablW-4bobA:
undetectable		 3ablN-4bobA:
15.65
3ablW-4bobA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 8 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.74A 3ag3N-4bobA:
undetectable
3ag3W-4bobA:
undetectable		 3ag3N-4bobA:
15.65
3ag3W-4bobA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 8 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.78A 3asnN-4bobA:
undetectable
3asnW-4bobA:
undetectable		 3asnN-4bobA:
15.65
3asnW-4bobA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 6 ASN A  45
TYR A 153
GLU A 109
ILE A 141
 None
 1.14A 3q5sA-4bobA:
undetectable		 3q5sA-4bobA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		3 / 3 GLU A 109
GLY A 138
SER A 111
 None
 0.46A 4b53B-4bobA:
undetectable		 4b53B-4bobA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 7 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.79A 5b1bN-4bobA:
undetectable
5b1bW-4bobA:
undetectable		 5b1bN-4bobA:
15.65
5b1bW-4bobA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 7 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.79A 5b3sN-4bobA:
undetectable
5b3sW-4bobA:
undetectable		 5b3sN-4bobA:
15.65
5b3sW-4bobA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		5 / 12 LEU A  52
PHE A  77
ILE A 121
GLY A 138
THR A 150
 None
 1.18A 5fsaB-4bobA:
undetectable		 5fsaB-4bobA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 7 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.70A 5iy5N-4bobA:
undetectable
5iy5W-4bobA:
undetectable		 5iy5N-4bobA:
15.65
5iy5W-4bobA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 8 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.80A 5xdxN-4bobA:
undetectable
5xdxW-4bobA:
undetectable		 5xdxN-4bobA:
15.65
5xdxW-4bobA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 8 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.80A 5zcoA-4bobA:
undetectable
5zcoJ-4bobA:
undetectable		 5zcoA-4bobA:
15.65
5zcoJ-4bobA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4bob ERPP PROTEIN
(Borreliella
burgdorferi) 		4 / 8 PHE A  78
MET A  92
THR A  93
LEU A 160
 None
 0.80A 5zcqN-4bobA:
undetectable
5zcqW-4bobA:
undetectable		 5zcqN-4bobA:
15.65
5zcqW-4bobA:
17.90