SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bop'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_A_LLTA261_1
(DEOXYCYTIDINE KINASE)		 4bop OTU
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 VAL A 329
LEU A 388
MET A 384
LEU A 321
GLU A 338
 None
 1.29A 3qeoA-4bopA:
0.0		 3qeoA-4bopA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 4bop OTU
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 TYR A 322
ALA A 383
ILE A 392
LEU A 388
 None
 1.06A 4uymB-4bopA:
undetectable		 4uymB-4bopA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 4bop OTU
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LYS A 327
ARG A 323
HIS A 336
 PO4  A1438 (-3.0A)
None
None
 1.10A 4zbrA-4bopA:
undetectable		 4zbrA-4bopA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 4bop OTU
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LYS A 309
VAL A 435
ASP A 437
 None
 0.67A 6fgdA-4bopA:
undetectable		 6fgdA-4bopA:
14.70