SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bos'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 4bos UBIQUITIN
THIOESTERASE OTU1
(Homo
sapiens) 		4 / 6 ALA A 297
SER A 229
ARG A 245
LEU A 298
 None
 1.11A 1gahA-4bosA:
undetectable		 1gahA-4bosA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 4bos UBIQUITIN
THIOESTERASE OTU1
(Homo
sapiens) 		5 / 12 GLY A 221
GLY A 220
THR A 218
ASP A 247
ILE A 223
 None
 1.05A 4pghD-4bosA:
undetectable		 4pghD-4bosA:
18.47