SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bpl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 7 LEU A 250
SER A 226
THR A 224
VAL A 179
 None
 1.02A 1dvxB-4bplA:
undetectable		 1dvxB-4bplA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		5 / 12 ILE A 488
GLY A 435
ALA A 396
SER A 398
TYR A 492
 None
 1.38A 1nbhA-4bplA:
undetectable		 1nbhA-4bplA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		5 / 12 ILE A 488
GLY A 435
ALA A 396
SER A 398
TYR A 492
 None
 1.38A 1nbhD-4bplA:
undetectable		 1nbhD-4bplA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 5 PHE A 228
LEU A 167
VAL A 164
VAL A 185
 None
 1.14A 1t88B-4bplA:
undetectable		 1t88B-4bplA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 LEU A 124
ALA A 178
SER A 169
SER A 170
 None
 1.01A 1tz8C-4bplA:
undetectable
1tz8D-4bplA:
undetectable		 1tz8C-4bplA:
12.92
1tz8D-4bplA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		3 / 3 ARG A  97
SER A  83
TYR A  82
 None
 0.75A 1x70A-4bplA:
undetectable		 1x70A-4bplA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		5 / 12 LEU A 293
LEU A 305
ILE A 351
LEU A 335
LEU A 332
 None
 0.95A 2bdmA-4bplA:
undetectable		 2bdmA-4bplA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 5 PHE A 228
LEU A 167
VAL A 164
VAL A 185
 None
 1.21A 2m56A-4bplA:
undetectable		 2m56A-4bplA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
NUCLEOPLASMIN NLS
(Oryza
sativa;
Xenopus) 		5 / 12 SER B 152
SER A 398
THR A 319
ALA A 392
VAL A 431
 None
 1.13A 2nniA-4bplB:
undetectable		 2nniA-4bplB:
3.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 8 LEU A 292
ILE A 251
HIS A 252
GLY A 284
 None
 0.96A 3b9lA-4bplA:
undetectable		 3b9lA-4bplA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		5 / 11 VAL A 280
GLY A 284
ILE A 251
THR A 307
LEU A 289
 None
 1.40A 3bf1E-4bplA:
undetectable
3bf1F-4bplA:
undetectable		 3bf1E-4bplA:
20.43
3bf1F-4bplA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 PHE A 228
LEU A 167
VAL A 164
VAL A 185
 None
 1.12A 3fwgA-4bplA:
undetectable		 3fwgA-4bplA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		5 / 12 LEU A 467
LEU A 433
LEU A 436
LEU A 440
LEU A 473
 None
 1.06A 3hm1A-4bplA:
undetectable		 3hm1A-4bplA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		5 / 12 ILE A 155
ALA A 201
ALA A 186
VAL A 185
ASN A 184
 None
 1.06A 3jb3A-4bplA:
undetectable		 3jb3A-4bplA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 PHE A 228
LEU A 167
VAL A 164
VAL A 185
 None
 1.08A 3wrhE-4bplA:
undetectable		 3wrhE-4bplA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 PHE A 228
LEU A 167
VAL A 164
VAL A 185
 None
 1.12A 3wrjE-4bplA:
undetectable		 3wrjE-4bplA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 THR A 307
GLY A 309
ILE A 322
LEU A 305
 None
 1.15A 4ac9C-4bplA:
undetectable		 4ac9C-4bplA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 THR A 307
GLY A 309
ILE A 322
LEU A 305
 None
 1.12A 4acaC-4bplA:
undetectable		 4acaC-4bplA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		5 / 11 SER A 114
GLY A 115
ILE A 108
LEU A 100
ILE A 143
 None
 1.10A 4dt8A-4bplA:
undetectable		 4dt8A-4bplA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 ALA A 246
ALA A 262
LEU A 225
THR A 222
 None
 1.08A 4dtzB-4bplA:
undetectable		 4dtzB-4bplA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 PHE A 228
LEU A 167
VAL A 164
VAL A 185
 None
 1.09A 4ek1A-4bplA:
undetectable		 4ek1A-4bplA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 PHE A 228
LEU A 167
VAL A 164
VAL A 185
 None
 1.07A 4g3rA-4bplA:
undetectable		 4g3rA-4bplA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 PHE A 228
LEU A 167
VAL A 164
VAL A 185
 None
 1.16A 4g3rB-4bplA:
undetectable		 4g3rB-4bplA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 5 PHE A 228
LEU A 167
VAL A 164
VAL A 185
 None
 1.14A 4l49A-4bplA:
undetectable		 4l49A-4bplA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 PHE A 228
LEU A 167
VAL A 164
VAL A 185
 None
 1.06A 4l4cA-4bplA:
undetectable		 4l4cA-4bplA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 4 VAL A 300
THR A 260
GLU A 256
GLU A 257
 None
 1.38A 4l78A-4bplA:
undetectable		 4l78A-4bplA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		4 / 6 ILE A 251
ILE A 311
SER A 270
LEU A 244
 None
 0.91A 4m51A-4bplA:
undetectable		 4m51A-4bplA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		5 / 12 GLY A 314
ASN A 274
ILE A 354
ASN A 310
THR A 350
 None
 1.36A 4pooA-4bplA:
undetectable		 4pooA-4bplA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		5 / 12 THR A 240
ALA A 243
LEU A 206
GLY A 200
LEU A 197
 None
 1.02A 4xi3B-4bplA:
undetectable		 4xi3B-4bplA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		5 / 12 THR A 240
ALA A 243
LEU A 206
GLY A 200
LEU A 197
 None
 1.01A 4xi3C-4bplA:
undetectable		 4xi3C-4bplA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		5 / 12 ALA A  92
LEU A  90
ALA A  76
GLY A  80
SER A  83
 None
 1.23A 5jglB-4bplA:
undetectable		 5jglB-4bplA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 4bpl IMPORTIN SUBUNIT
ALPHA-1A
(Oryza
sativa) 		3 / 3 PHE A 123
ARG A 126
GLN A 122
 None
 1.07A 6g1pB-4bplA:
undetectable		 6g1pB-4bplA:
24.15