SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bqq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4bqq INTEGRASE
(Streptomyces
virus
phiC31) 		4 / 8 PHE A  94
GLY A   6
VAL A 114
ILE A 116
 None
 0.64A 2a1mB-4bqqA:
undetectable		 2a1mB-4bqqA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 4bqq INTEGRASE
(Streptomyces
virus
phiC31) 		4 / 8 THR A 258
VAL A 277
THR A 276
ASP A 252
 None
 0.85A 2qbmA-4bqqA:
undetectable		 2qbmA-4bqqA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 4bqq INTEGRASE
(Streptomyces
virus
phiC31) 		5 / 11 THR A 206
GLY A 207
PRO A 208
PRO A 257
ASP A 254
 None
 1.25A 3t8nD-4bqqA:
undetectable
3t8nF-4bqqA:
undetectable		 3t8nD-4bqqA:
15.74
3t8nF-4bqqA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4bqq INTEGRASE
(Streptomyces
virus
phiC31) 		4 / 7 ALA A 287
ILE A 329
HIS A 200
GLY A 327
 None
 0.83A 3v4tH-4bqqA:
undetectable		 3v4tH-4bqqA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 4bqq INTEGRASE
(Streptomyces
virus
phiC31) 		4 / 7 GLY A   6
ILE A 116
LEU A 109
PHE A  94
 None
 0.77A 4ejjD-4bqqA:
undetectable		 4ejjD-4bqqA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 4bqq INTEGRASE
(Streptomyces
virus
phiC31) 		4 / 5 ARG A  13
SER A  95
SER A  92
SER A  12
 None
 1.46A 5hswA-4bqqA:
undetectable		 5hswA-4bqqA:
21.87