SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bs2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 8 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.10A 3b3pA-4bs2A:
undetectable
3b3pB-4bs2A:
undetectable		 3b3pA-4bs2A:
15.87
3b3pB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.15A 3jt8A-4bs2A:
undetectable
3jt8B-4bs2A:
undetectable		 3jt8A-4bs2A:
15.87
3jt8B-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.19A 3jt9A-4bs2A:
undetectable
3jt9B-4bs2A:
undetectable		 3jt9A-4bs2A:
15.87
3jt9B-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.20A 3jwtA-4bs2A:
undetectable
3jwtB-4bs2A:
undetectable		 3jwtA-4bs2A:
15.87
3jwtB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.16A 3n5vA-4bs2A:
undetectable
3n5vB-4bs2A:
undetectable		 3n5vA-4bs2A:
15.87
3n5vB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.18A 3nlmA-4bs2A:
undetectable
3nlmB-4bs2A:
undetectable		 3nlmA-4bs2A:
15.87
3nlmB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.24A 3nlnA-4bs2A:
undetectable
3nlnB-4bs2A:
undetectable		 3nlnA-4bs2A:
15.87
3nlnB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.19A 3nloA-4bs2A:
undetectable
3nloB-4bs2A:
undetectable		 3nloA-4bs2A:
15.87
3nloB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.21A 3nlxA-4bs2A:
undetectable
3nlxB-4bs2A:
undetectable		 3nlxA-4bs2A:
15.87
3nlxB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.20A 3nm0A-4bs2A:
undetectable
3nm0B-4bs2A:
undetectable		 3nm0A-4bs2A:
15.87
3nm0B-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.20A 3nnyA-4bs2A:
undetectable
3nnyB-4bs2A:
undetectable		 3nnyA-4bs2A:
15.87
3nnyB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.18A 3pneA-4bs2A:
undetectable
3pneB-4bs2A:
undetectable		 3pneA-4bs2A:
15.87
3pneB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.19A 3pnfA-4bs2A:
undetectable
3pnfB-4bs2A:
undetectable		 3pnfA-4bs2A:
15.87
3pnfB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.19A 3pngA-4bs2A:
undetectable
3pngB-4bs2A:
undetectable		 3pngA-4bs2A:
15.87
3pngB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.15A 3q99A-4bs2A:
undetectable
3q99B-4bs2A:
undetectable		 3q99A-4bs2A:
15.87
3q99B-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.20A 3rqmA-4bs2A:
undetectable
3rqmB-4bs2A:
undetectable		 3rqmA-4bs2A:
15.87
3rqmB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.11A 3ufoA-4bs2A:
undetectable
3ufoB-4bs2A:
undetectable		 3ufoA-4bs2A:
15.87
3ufoB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.12A 3ufpA-4bs2A:
undetectable
3ufpB-4bs2A:
undetectable		 3ufpA-4bs2A:
15.87
3ufpB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.04A 3ufpA-4bs2A:
undetectable
3ufpB-4bs2A:
undetectable		 3ufpA-4bs2A:
15.87
3ufpB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.07A 3ufrA-4bs2A:
undetectable
3ufrB-4bs2A:
undetectable		 3ufrA-4bs2A:
15.87
3ufrB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.11A 3ufsA-4bs2A:
undetectable
3ufsB-4bs2A:
undetectable		 3ufsA-4bs2A:
15.87
3ufsB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.07A 3ufsA-4bs2A:
undetectable
3ufsB-4bs2A:
undetectable		 3ufsA-4bs2A:
15.87
3ufsB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.10A 3uftA-4bs2A:
undetectable
3uftB-4bs2A:
undetectable		 3uftA-4bs2A:
15.87
3uftB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.08A 4c39A-4bs2A:
undetectable
4c39B-4bs2A:
undetectable		 4c39A-4bs2A:
15.87
4c39B-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.19A 4caoA-4bs2A:
undetectable
4caoB-4bs2A:
undetectable		 4caoA-4bs2A:
15.87
4caoB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.11A 4ctqA-4bs2A:
undetectable
4ctqB-4bs2A:
undetectable		 4ctqA-4bs2A:
15.87
4ctqB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.15A 4ctrA-4bs2A:
undetectable
4ctrB-4bs2A:
undetectable		 4ctrA-4bs2A:
15.87
4ctrB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.11A 4cttA-4bs2A:
undetectable
4cttB-4bs2A:
undetectable		 4cttA-4bs2A:
15.87
4cttB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.23A 4ctwA-4bs2A:
undetectable
4ctwB-4bs2A:
undetectable		 4ctwA-4bs2A:
15.87
4ctwB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.19A 4cx5A-4bs2A:
undetectable
4cx5B-4bs2A:
undetectable		 4cx5A-4bs2A:
16.25
4cx5B-4bs2A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.20A 4fvxA-4bs2A:
undetectable
4fvxB-4bs2A:
undetectable		 4fvxA-4bs2A:
15.87
4fvxB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.23A 4jsjA-4bs2A:
undetectable
4jsjB-4bs2A:
undetectable		 4jsjA-4bs2A:
15.87
4jsjB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.15A 4k5fA-4bs2A:
undetectable
4k5fB-4bs2A:
undetectable		 4k5fA-4bs2A:
15.87
4k5fB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.17A 4kchA-4bs2A:
undetectable
4kchB-4bs2A:
undetectable		 4kchA-4bs2A:
15.87
4kchB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.07A 4luxA-4bs2A:
undetectable
4luxB-4bs2A:
undetectable		 4luxA-4bs2A:
15.87
4luxB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.06A 4v3vA-4bs2A:
undetectable
4v3vB-4bs2A:
undetectable		 4v3vA-4bs2A:
15.87
4v3vB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.12A 5ad4A-4bs2A:
undetectable
5ad4B-4bs2A:
undetectable		 5ad4A-4bs2A:
15.87
5ad4B-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.14A 5ad6A-4bs2A:
undetectable
5ad6B-4bs2A:
undetectable		 5ad6A-4bs2A:
15.87
5ad6B-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.05A 5agoA-4bs2A:
undetectable
5agoB-4bs2A:
undetectable		 5agoA-4bs2A:
15.87
5agoB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 VAL A 220
ILE A 222
VAL A 195
ALA A 230
 None
 0.72A 5osrA-4bs2A:
undetectable		 5osrA-4bs2A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.11A 5unuA-4bs2A:
undetectable
5unuB-4bs2A:
undetectable		 5unuA-4bs2A:
15.87
5unuB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.07A 5unwA-4bs2A:
undetectable
5unwB-4bs2A:
undetectable		 5unwA-4bs2A:
15.87
5unwB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.08A 5unwA-4bs2A:
undetectable
5unwB-4bs2A:
undetectable		 5unwA-4bs2A:
15.87
5unwB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.08A 5unyA-4bs2A:
undetectable
5unyB-4bs2A:
undetectable		 5unyA-4bs2A:
15.87
5unyB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.06A 5unzA-4bs2A:
undetectable
5unzB-4bs2A:
undetectable		 5unzA-4bs2A:
15.87
5unzB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.08A 5uo0A-4bs2A:
undetectable
5uo0B-4bs2A:
undetectable		 5uo0A-4bs2A:
15.87
5uo0B-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.12A 5uo3A-4bs2A:
undetectable
5uo3B-4bs2A:
undetectable		 5uo3A-4bs2A:
17.81
5uo3B-4bs2A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.13A 5uo4A-4bs2A:
undetectable
5uo4B-4bs2A:
undetectable		 5uo4A-4bs2A:
17.81
5uo4B-4bs2A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.17A 5vumA-4bs2A:
undetectable
5vumB-4bs2A:
undetectable		 5vumA-4bs2A:
15.87
5vumB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.05A 5vuqA-4bs2A:
undetectable
5vuqB-4bs2A:
undetectable		 5vuqA-4bs2A:
15.87
5vuqB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.07A 5vurA-4bs2A:
undetectable
5vurB-4bs2A:
undetectable		 5vurA-4bs2A:
15.87
5vurB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.03A 5vusA-4bs2A:
undetectable
5vusB-4bs2A:
undetectable		 5vusA-4bs2A:
15.87
5vusB-4bs2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.10A 5vuvA-4bs2A:
undetectable
5vuvB-4bs2A:
undetectable		 5vuvA-4bs2A:
17.81
5vuvB-4bs2A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.13A 5vuyA-4bs2A:
undetectable
5vuyB-4bs2A:
undetectable		 5vuyA-4bs2A:
17.81
5vuyB-4bs2A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.13A 5vuyA-4bs2A:
undetectable
5vuyB-4bs2A:
undetectable		 5vuyA-4bs2A:
17.81
5vuyB-4bs2A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.08A 5vv3A-4bs2A:
undetectable
5vv3B-4bs2A:
undetectable		 5vv3A-4bs2A:
17.81
5vv3B-4bs2A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 MET A 202
VAL A 220
PHE A 211
GLU A 206
 None
 1.21A 5vv5A-4bs2A:
undetectable
5vv5B-4bs2A:
undetectable		 5vv5A-4bs2A:
17.81
5vv5B-4bs2A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 7 PHE A 211
GLU A 206
MET A 202
VAL A 220
 None
 1.09A 5vv5A-4bs2A:
undetectable
5vv5B-4bs2A:
undetectable		 5vv5A-4bs2A:
17.81
5vv5B-4bs2A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 4bs2 TAR DNA-BINDING
PROTEIN 43
(Homo
sapiens) 		4 / 6 GLN A 158
GLU A 154
HIS A  98
ALA A 100
 None
 1.27A 6f6jC-4bs2A:
undetectable
6f6jD-4bs2A:
undetectable		 6f6jC-4bs2A:
20.73
6f6jD-4bs2A:
20.73