SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bsk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HDN_J_TACJ5888_1 (ELONGATION FACTOR EF-TU)	4bsk	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 (Homo sapiens)	4 / 6	ASP A 187 PRO A 163 SER A 38 VAL A 40	None	1.18A	2hdnI-4bskA: undetectable 2hdnJ-4bskA: undetectable 2hdnL-4bskA: undetectable	2hdnI-4bskA: 9.48 2hdnJ-4bskA: 20.12 2hdnL-4bskA: 20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HDN_L_TACL6888_1 (ELONGATION FACTOR EF-TU)	4bsk	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 (Homo sapiens)	4 / 6	SER A 38 VAL A 40 ASP A 187 PRO A 163	None	1.07A	2hdnJ-4bskA: undetectable 2hdnK-4bskA: undetectable 2hdnL-4bskA: undetectable	2hdnJ-4bskA: 20.12 2hdnK-4bskA: 9.48 2hdnL-4bskA: 20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IZQ_C_DVAC8_0 (GRAMICIDIN D)	4bsk	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 (Homo sapiens)	3 / 3	VAL A 193 TRP A 155 VAL A 156	None	0.86A	2izqC-4bskA: undetectable 2izqD-4bskA: undetectable	2izqC-4bskA: 6.35 2izqD-4bskA: 6.35

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HDN_J_TACJ5888_1","ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU","4bsk","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3","Homo sapiens",4,"ASP A 187;PRO A 163;SER A  38;VAL A  40","None","1.18A","2hdnI-4bskA:undetectable;2hdnJ-4bskA:undetectable;2hdnL-4bskA:undetectable","2hdnI-4bskA:9.48;2hdnJ-4bskA:20.12;2hdnL-4bskA:20.12"],["2HDN_L_TACL6888_1","ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU","4bsk","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3","Homo sapiens",4,"SER A  38;VAL A  40;ASP A 187;PRO A 163","None","1.07A","2hdnJ-4bskA:undetectable;2hdnK-4bskA:undetectable;2hdnL-4bskA:undetectable","2hdnJ-4bskA:20.12;2hdnK-4bskA:9.48;2hdnL-4bskA:20.12"],["2IZQ_C_DVAC8_0","GRAMICIDIN D","4bsk","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3","Homo sapiens",3,"VAL A 193;TRP A 155;VAL A 156","None","0.86A","2izqC-4bskA:undetectable;2izqD-4bskA:undetectable","2izqC-4bskA:6.35;2izqD-4bskA:6.35"]]