SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bsx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 4bsx TIR
DOMAIN-CONTAINING
ADAPTER MOLECULE 1
(Homo
sapiens) 		4 / 8 LEU A  26
LEU A 102
GLU A 106
LEU A  15
 None
 0.76A 1eupA-4bsxA:
undetectable		 1eupA-4bsxA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 4bsx TIR
DOMAIN-CONTAINING
ADAPTER MOLECULE 1
(Homo
sapiens) 		4 / 6 LEU A   8
LEU A  43
LEU A  42
LEU A  49
 None
 1.02A 2ab2A-4bsxA:
undetectable		 2ab2A-4bsxA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_0
(CATECHOL
O-METHYLTRANSFERASE)		 4bsx TIR
DOMAIN-CONTAINING
ADAPTER MOLECULE 1
(Homo
sapiens) 		5 / 12 VAL A  96
GLU A 120
TYR A 118
TYR A 100
SER A 127
 None
 1.48A 3a7eA-4bsxA:
0.1		 3a7eA-4bsxA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 4bsx TIR
DOMAIN-CONTAINING
ADAPTER MOLECULE 1
(Homo
sapiens) 		5 / 9 GLY A  39
GLN A  38
ARG A 143
LEU A  99
LEU A 102
 None
 1.42A 3nbqD-4bsxA:
undetectable		 3nbqD-4bsxA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 4bsx TIR
DOMAIN-CONTAINING
ADAPTER MOLECULE 1
(Homo
sapiens) 		5 / 12 ALA A  97
SER A  93
GLU A 139
GLY A 134
LEU A 125
 None
 0.93A 4uilH-4bsxA:
undetectable
4uilL-4bsxA:
undetectable		 4uilH-4bsxA:
20.26
4uilL-4bsxA:
21.20