SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bsz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FK6_A_LNLA1201_1 (NON-SPECIFIC LIPID TRANSFER PROTEIN)	4bsz	ANKYRIN REPEAT-CONTAINING PROTEIN YAR1 (Saccharomyces cerevisiae)	5 / 12	LEU B 112 ALA B 100 ALA B 96 LEU B 54 ILE B 69	None	1.06A	1fk6A-4bszB: undetectable	1fk6A-4bszB: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R2V_C_ACTC36_0 (GCN4 LEUCINE ZIPPER)	4bsz	ANKYRIN REPEAT-CONTAINING PROTEIN YAR1 (Saccharomyces cerevisiae)	5 / 10	HIS B 55 ALA B 59 ASN B 103 ALA B 100 ALA B 58	None	1.27A	2r2vC-4bszB: undetectable 2r2vF-4bszB: undetectable 2r2vG-4bszB: undetectable	2r2vC-4bszB: 11.11 2r2vF-4bszB: 11.11 2r2vG-4bszB: 11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB2_A_SAMA1102_1 (STRUCTURAL PROTEIN VP3)	4bsz	ANKYRIN REPEAT-CONTAINING PROTEIN YAR1 (Saccharomyces cerevisiae)	3 / 3	ARG B 123 ASP B 119 ASP B 129	None	0.85A	3jb2A-4bszB: undetectable	3jb2A-4bszB: 11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F88_A_STRA502_1 (CYTOCHROME P450 CYP260A1)	4bsz	ANKYRIN REPEAT-CONTAINING PROTEIN YAR1 (Saccharomyces cerevisiae)	4 / 6	LEU B 112 ALA B 118 THR B 52 ASN B 90	None	0.85A	6f88A-4bszB: undetectable	6f88A-4bszB: 18.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FK6_A_LNLA1201_1","NON-SPECIFIC LIPID TRANSFER PROTEIN","4bsz","ANKYRIN REPEAT-CONTAINING PROTEIN YAR1","Saccharomyces cerevisiae",5,"LEU B 112;ALA B 100;ALA B  96;LEU B  54;ILE B  69","None","1.06A","1fk6A-4bszB:undetectable","1fk6A-4bszB:16.67"],["2R2V_C_ACTC36_0","GCN4 LEUCINE ZIPPER","4bsz","ANKYRIN REPEAT-CONTAINING PROTEIN YAR1","Saccharomyces cerevisiae",5,"HIS B  55;ALA B  59;ASN B 103;ALA B 100;ALA B  58","None","1.27A","2r2vC-4bszB:undetectable;2r2vF-4bszB:undetectable;2r2vG-4bszB:undetectable","2r2vC-4bszB:11.11;2r2vF-4bszB:11.11;2r2vG-4bszB:11.11"],["3JB2_A_SAMA1102_1","STRUCTURAL PROTEIN VP3","4bsz","ANKYRIN REPEAT-CONTAINING PROTEIN YAR1","Saccharomyces cerevisiae",3,"ARG B 123;ASP B 119;ASP B 129","None","0.85A","3jb2A-4bszB:undetectable","3jb2A-4bszB:11.95"],["6F88_A_STRA502_1","CYTOCHROME P450 CYP260A1","4bsz","ANKYRIN REPEAT-CONTAINING PROTEIN YAR1","Saccharomyces cerevisiae",4,"LEU B 112;ALA B 118;THR B  52;ASN B  90","None","0.85A","6f88A-4bszB:undetectable","6f88A-4bszB:18.40"]]