SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bt1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4bt1 TRANSCRIPTIONAL
REGULATOR
(Escherichia
virus
Mu) 		4 / 6 LEU B 194
PHE B 204
LEU B 208
PHE B 227
 None
 1.00A 3abkP-4bt1B:
undetectable
3abkW-4bt1B:
undetectable		 3abkP-4bt1B:
18.22
3abkW-4bt1B:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 4bt1 TRANSCRIPTIONAL
REGULATOR
(Escherichia
virus
Mu) 		3 / 3 ARG A 330
LYS A 331
LYS A 327
 None
 0.99A 4k50A-4bt1A:
undetectable		 4k50A-4bt1A:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 4bt1 TRANSCRIPTIONAL
REGULATOR
(Escherichia
virus
Mu) 		3 / 3 ARG A 330
LYS A 331
LYS A 327
 None
 0.87A 4k50E-4bt1A:
undetectable		 4k50E-4bt1A:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 4bt1 TRANSCRIPTIONAL
REGULATOR
(Escherichia
virus
Mu) 		3 / 3 ARG A 330
LYS A 331
LYS A 327
 None
 0.92A 4k50I-4bt1A:
undetectable		 4k50I-4bt1A:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4bt1 TRANSCRIPTIONAL
REGULATOR
(Escherichia
virus
Mu) 		4 / 7 LEU A 380
LEU A 347
ALA A 321
ALA A 366
 None
 0.66A 4z90F-4bt1A:
undetectable
4z90G-4bt1A:
undetectable
4z90H-4bt1A:
undetectable
4z90J-4bt1A:
undetectable		 4z90F-4bt1A:
12.85
4z90G-4bt1A:
12.85
4z90H-4bt1A:
12.85
4z90J-4bt1A:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 4bt1 TRANSCRIPTIONAL
REGULATOR
(Escherichia
virus
Mu) 		4 / 5 GLU B 242
ALA B 197
GLU B 239
ASN B 280
 None
 1.20A 5dwkC-4bt1B:
undetectable		 5dwkC-4bt1B:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4bt1 TRANSCRIPTIONAL
REGULATOR
(Escherichia
virus
Mu) 		4 / 5 LEU B 194
PHE B 204
LEU B 208
PHE B 227
 None
 0.97A 5x19C-4bt1B:
undetectable
5x19J-4bt1B:
undetectable		 5x19C-4bt1B:
18.22
5x19J-4bt1B:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 4bt1 TRANSCRIPTIONAL
REGULATOR
(Escherichia
virus
Mu) 		5 / 12 PRO B 190
PHE B 191
VAL B 271
PHE B 204
PHE B 227
 None
 1.20A 6becA-4bt1B:
undetectable
6becB-4bt1B:
undetectable
6becC-4bt1B:
undetectable		 6becA-4bt1B:
15.18
6becB-4bt1B:
15.18
6becC-4bt1B:
15.18