SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4btf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		5 / 12 LEU A  61
LEU A  38
ILE A   8
GLY A  11
LEU A  68
 None
 1.07A 2ouzA-4btfA:
undetectable		 2ouzA-4btfA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		3 / 3 ASN A  33
ARG A  30
ASP A 143
 None
 0.92A 2qe6A-4btfA:
undetectable		 2qe6A-4btfA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		3 / 3 ASN A  33
ARG A  30
ASP A 143
 None
 0.89A 2qe6B-4btfA:
undetectable		 2qe6B-4btfA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IEO_A_AMJA300_0
(CARBONIC ANHYDRASE 2)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		4 / 4 ILE A 259
GLN A 261
VAL A 229
PHE A 268
 None
 1.40A 3ieoA-4btfA:
undetectable		 3ieoA-4btfA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		3 / 3 GLN A 331
GLU A 273
LYS A 333
 None
 1.14A 3su9A-4btfA:
undetectable		 3su9A-4btfA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		4 / 5 ASP A 289
THR A 291
LEU A 290
GLU A 287
 None
 0.86A 4a3pA-4btfA:
undetectable		 4a3pA-4btfA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		4 / 7 GLU A 338
ILE A 254
PHE A 337
VAL A 388
 None
 1.09A 4a97A-4btfA:
3.8		 4a97A-4btfA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		4 / 7 GLU A 338
ILE A 254
PHE A 337
VAL A 388
 None
 1.06A 4a97D-4btfA:
3.9		 4a97D-4btfA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		4 / 6 GLU A 338
ILE A 254
PHE A 337
VAL A 388
 None
 1.05A 4a97I-4btfA:
3.7		 4a97I-4btfA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		5 / 10 LEU A 389
ILE A 387
ILE A 392
PHE A 385
SER A 384
 None
 0.94A 4fakA-4btfA:
undetectable		 4fakA-4btfA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		5 / 12 LEU A  45
LEU A 111
GLY A  37
HIS A  36
LEU A  39
 None
 1.25A 4j26A-4btfA:
undetectable		 4j26A-4btfA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Mus
musculus) 		5 / 12 VAL A 326
LEU A 389
ILE A 392
LEU A 280
LEU A 453
 None
 1.15A 5ienA-4btfA:
undetectable		 5ienA-4btfA:
15.43