SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4btg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 8 SER A 193
VAL A 328
SER A 329
ASP A 188
 None
 1.15A 1hwkC-4btgA:
undetectable		 1hwkC-4btgA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 8 SER A 193
VAL A 328
SER A 329
ASP A 188
 None
 1.16A 1hwkD-4btgA:
undetectable		 1hwkD-4btgA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 PHE A 291
LEU A 290
PHE A 484
LEU A 186
LEU A 516
 None
 1.23A 1og5A-4btgA:
undetectable		 1og5A-4btgA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 4 SER A 539
ILE A 535
VAL A  31
THR A  17
 None
 1.02A 1u70A-4btgA:
undetectable		 1u70A-4btgA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 LEU A 439
GLY A 440
VAL A 457
HIS A 630
ILE A 632
 None
 1.32A 1z95A-4btgA:
undetectable		 1z95A-4btgA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 5 LEU A 462
PRO A 455
ALA A 458
ILE A 459
 None
 0.81A 2aofB-4btgA:
undetectable		 2aofB-4btgA:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 11 GLU A 500
VAL A 501
HIS A 506
ILE A  22
PHE A 291
 None
 1.30A 2dg3A-4btgA:
undetectable		 2dg3A-4btgA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_E_H4BE1004_1
(HYPOTHETICAL PROTEIN
PH0634)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 11 PHE A 413
HIS A 357
VAL A 420
THR A 418
GLU A 642
 None
 1.32A 2dttD-4btgA:
undetectable
2dttE-4btgA:
undetectable		 2dttD-4btgA:
10.60
2dttE-4btgA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 7 ILE A 708
GLN A 695
ASP A 700
GLY A 704
 None
 0.96A 2qqcD-4btgA:
undetectable
2qqcE-4btgA:
undetectable		 2qqcD-4btgA:
11.83
2qqcE-4btgA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		3 / 3 TYR A 532
GLU A 547
THR A 524
 None
 0.89A 2y7hB-4btgA:
1.1		 2y7hB-4btgA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 8 PHE A 331
ILE A 322
ALA A 192
VAL A 250
 None
 0.89A 3me6B-4btgA:
undetectable		 3me6B-4btgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		3 / 3 VAL A 190
VAL A 253
SER A 251
 None
 0.69A 3n8xB-4btgA:
undetectable		 3n8xB-4btgA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 PHE A  40
ALA A 293
LEU A 290
ILE A 322
SER A 326
 None
 1.17A 3nrrA-4btgA:
undetectable		 3nrrA-4btgA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 5 LYS A 677
VAL A 749
ILE A 678
ARG A 417
 None
 1.43A 3pyyB-4btgA:
undetectable		 3pyyB-4btgA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 11 PRO A 554
SER A 347
ILE A 349
HIS A 497
ILE A 549
 None
 1.21A 3rf4A-4btgA:
undetectable
3rf4C-4btgA:
undetectable		 3rf4A-4btgA:
10.62
3rf4C-4btgA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S7B_A_SAMA1000_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 11 GLU A 142
HIS A 143
HIS A  93
TYR A  92
PHE A  89
 None
 1.44A 3s7bA-4btgA:
0.2		 3s7bA-4btgA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S7F_A_SAMA1000_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2
P53 PEPTIDE)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 GLU A 142
HIS A 143
HIS A  93
TYR A  92
PHE A  89
 None
 1.45A 3s7fA-4btgA:
0.2
3s7fI-4btgA:
undetectable		 3s7fA-4btgA:
21.20
3s7fI-4btgA:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S7J_A_SAMA1000_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 11 GLU A 142
HIS A 143
HIS A  93
TYR A  92
PHE A  89
 None
 1.41A 3s7jA-4btgA:
0.0		 3s7jA-4btgA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TF1_A_ACTA191_0
(METHYL-ACCEPTING
CHEMOTAXIS PROTEIN)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 5 THR A 150
ILE A 149
PHE A  89
LEU A 202
 None
 1.40A 3tf1A-4btgA:
undetectable		 3tf1A-4btgA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 LEU A 132
ILE A 575
GLY A  57
ILE A  61
HIS A 148
 None
 1.02A 3uj6A-4btgA:
undetectable		 3uj6A-4btgA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 ALA A 550
ILE A 343
GLU A 559
LEU A 439
VAL A 360
 None
 1.12A 4azsA-4btgA:
undetectable		 4azsA-4btgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 ALA A 550
ILE A 343
GLU A 559
LEU A 439
VAL A 360
 None
 1.14A 4azwA-4btgA:
undetectable		 4azwA-4btgA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 8 SER A 741
SER A 739
TYR A 637
ILE A 633
 None
 1.26A 4ms4A-4btgA:
undetectable		 4ms4A-4btgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 LEU A 439
GLY A 440
VAL A 457
HIS A 630
ILE A 632
 None
 1.37A 4okbA-4btgA:
undetectable		 4okbA-4btgA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 LEU A 439
GLY A 440
VAL A 457
HIS A 630
ILE A 632
 None
 1.33A 4okwA-4btgA:
undetectable		 4okwA-4btgA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		3 / 3 PRO A 455
MET A 456
TYR A 449
 None
 0.99A 4qa0A-4btgA:
undetectable		 4qa0A-4btgA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		3 / 3 PRO A 455
MET A 456
TYR A 449
 None
 0.94A 4qa2B-4btgA:
undetectable		 4qa2B-4btgA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 8 GLU A 642
ASP A 644
ASP A 643
TYR A 421
 None
 1.41A 4qb9D-4btgA:
undetectable		 4qb9D-4btgA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 7 LEU A 526
GLU A 525
ILE A 528
VAL A 530
 None
 1.12A 4tvtA-4btgA:
undetectable		 4tvtA-4btgA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 GLY A 687
GLY A 682
GLY A 728
TRP A 726
ALA A 688
 None
 0.91A 4uciA-4btgA:
undetectable		 4uciA-4btgA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 GLY A 687
GLY A 682
GLY A 728
TRP A 726
ALA A 688
 None
 0.91A 4uciB-4btgA:
undetectable		 4uciB-4btgA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 12 GLY A 687
GLY A 682
GLY A 728
TRP A 726
ALA A 688
 None
 0.91A 4uckA-4btgA:
undetectable		 4uckA-4btgA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KJK_A_SAMA501_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 11 GLU A 142
HIS A 143
HIS A  93
TYR A  92
PHE A  89
 None
 1.43A 5kjkA-4btgA:
0.2		 5kjkA-4btgA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KJL_A_SAMA501_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 11 GLU A 142
HIS A 143
HIS A  93
TYR A  92
PHE A  89
 None
 1.42A 5kjlA-4btgA:
0.0		 5kjlA-4btgA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KJM_A_SAMA501_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 11 GLU A 142
HIS A 143
HIS A  93
TYR A  92
PHE A  89
 None
 1.45A 5kjmA-4btgA:
0.2		 5kjmA-4btgA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KJN_A_SAMA501_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 11 GLU A 142
HIS A 143
HIS A  93
TYR A  92
PHE A  89
 None
 1.39A 5kjnA-4btgA:
0.1		 5kjnA-4btgA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		4 / 8 PRO A 181
THR A 177
TRP A 364
PRO A 442
 None
 1.36A 5x2sI-4btgA:
undetectable
5x2sJ-4btgA:
undetectable
5x2sK-4btgA:
undetectable		 5x2sI-4btgA:
10.39
5x2sJ-4btgA:
12.30
5x2sK-4btgA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		5 / 10 LEU A 333
ILE A 322
LEU A 284
LEU A 288
ALA A 289
 None
 1.20A 5y7pG-4btgA:
undetectable		 5y7pG-4btgA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4btg MAJOR INNER PROTEIN
P1
(Pseudomonas
virus
phi6) 		3 / 3 LYS A  58
ASN A  60
SER A 159
 None
 1.29A 5yw0A-4btgA:
undetectable		 5yw0A-4btgA:
17.92