SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4btp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.66A 1a7yA-4btpA:
undetectable		 1a7yA-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.77A 1a7yB-4btpA:
undetectable		 1a7yB-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 298
 None
 0.89A 1a7yB-4btpA:
undetectable		 1a7yB-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.71A 1a7yB-4btpA:
undetectable		 1a7yB-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 4btp P1
(Pseudomonas
phage
phi8) 		4 / 8 SER A 524
ARG A 286
ALA A  37
PHE A  32
 None
 1.04A 1dmiA-4btpA:
undetectable
1dmiB-4btpA:
undetectable		 1dmiA-4btpA:
20.85
1dmiB-4btpA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.90A 1dscC-4btpA:
undetectable		 1dscC-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.78A 1fjaC-4btpA:
undetectable		 1fjaC-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.78A 1fjaD-4btpA:
undetectable		 1fjaD-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.73A 1i3wE-4btpA:
undetectable		 1i3wE-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.68A 1i3wE-4btpA:
undetectable		 1i3wE-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.68A 1i3wF-4btpA:
undetectable		 1i3wF-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.69A 1i3wG-4btpA:
undetectable		 1i3wG-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.73A 1i3wG-4btpA:
undetectable		 1i3wG-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.70A 1i3wH-4btpA:
undetectable		 1i3wH-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 11 LEU A 485
ALA A 391
MET A 450
LEU A 446
ARG A 464
 None
 1.21A 1iiuA-4btpA:
undetectable		 1iiuA-4btpA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 ALA A 383
ALA A 391
MET A 450
LEU A 446
ARG A 464
 None
 1.40A 1kt5A-4btpA:
undetectable		 1kt5A-4btpA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 LEU A 485
ALA A 391
MET A 450
LEU A 446
ARG A 464
 None
 1.23A 1kt5A-4btpA:
undetectable		 1kt5A-4btpA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.70A 1mnvD-4btpA:
undetectable		 1mnvD-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.71A 1mnvD-4btpA:
undetectable		 1mnvD-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 TYR A 638
GLU A 737
GLY A 716
ALA A 649
LEU A 656
 None
 1.05A 1nw3A-4btpA:
undetectable		 1nw3A-4btpA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.67A 1ovfB-4btpA:
undetectable		 1ovfB-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.66A 1qfiA-4btpA:
undetectable		 1qfiA-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.71A 1qfiB-4btpA:
undetectable		 1qfiB-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 10 LEU A 485
ALA A 391
VAL A 476
MET A 450
LEU A 446
 None
 1.19A 1rlbE-4btpA:
undetectable		 1rlbE-4btpA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.71A 1unjF-4btpA:
undetectable		 1unjF-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.68A 1unjF-4btpA:
undetectable		 1unjF-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.69A 1unjL-4btpA:
undetectable		 1unjL-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.70A 1unjL-4btpA:
undetectable		 1unjL-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.70A 1unjR-4btpA:
undetectable		 1unjR-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.71A 1unjR-4btpA:
undetectable		 1unjR-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.74A 1unjW-4btpA:
undetectable		 1unjW-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.70A 1unjX-4btpA:
undetectable		 1unjX-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.68A 1unjX-4btpA:
undetectable		 1unjX-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.71A 1unmE-4btpA:
undetectable		 1unmE-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.74A 1unmE-4btpA:
undetectable		 1unmE-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.71A 1unmF-4btpA:
undetectable		 1unmF-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.77A 1unmF-4btpA:
undetectable		 1unmF-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 4btp P1
(Pseudomonas
phage
phi8) 		4 / 5 LEU A 496
GLY A 494
ILE A 584
PHE A  53
 None
 0.90A 1xf1A-4btpA:
undetectable		 1xf1A-4btpA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 295
THR A 297
PRO A 299
 None
 0.84A 209dC-4btpA:
undetectable		 209dC-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.90A 316dC-4btpA:
undetectable		 316dC-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 GLY A 687
LEU A 485
LEU A 486
VAL A 487
MET A 450
 None
 1.25A 3adsB-4btpA:
undetectable		 3adsB-4btpA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 4btp P1
(Pseudomonas
phage
phi8) 		4 / 8 ILE A 353
PHE A 366
PHE A 291
PHE A 193
 None
 1.04A 3ko0B-4btpA:
1.6
3ko0J-4btpA:
1.5		 3ko0B-4btpA:
9.18
3ko0J-4btpA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 4btp P1
(Pseudomonas
phage
phi8) 		4 / 8 ILE A 353
PHE A 366
PHE A 291
PHE A 193
 None
 1.03A 3ko0K-4btpA:
1.5
3ko0S-4btpA:
1.5		 3ko0K-4btpA:
9.18
3ko0S-4btpA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 10 LEU A 256
ALA A 356
ILE A 353
VAL A 262
LEU A 259
 None
 0.99A 3ogpB-4btpA:
undetectable		 3ogpB-4btpA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 TYR A 638
GLU A 737
GLY A 716
ALA A 649
ASP A 652
 None
 1.27A 3qowA-4btpA:
undetectable		 3qowA-4btpA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 LEU A 220
SER A 167
ALA A 122
ILE A 227
VAL A 124
 None
 1.03A 3w67C-4btpA:
undetectable		 3w67C-4btpA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4btp P1
(Pseudomonas
phage
phi8) 		4 / 5 TYR A 397
LEU A 497
TYR A 491
LEU A 486
 None
 1.46A 4em2A-4btpA:
0.0		 4em2A-4btpA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 THR A 297
PRO A 299
THR A 295
 None
 0.72A 4hivD-4btpA:
undetectable		 4hivD-4btpA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 ALA A 610
THR A 423
ILE A 425
LEU A 593
ILE A 607
 None
 1.08A 4kjkA-4btpA:
undetectable		 4kjkA-4btpA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 4btp P1
(Pseudomonas
phage
phi8) 		6 / 11 PRO A 650
VAL A 636
ALA A 648
TYR A 638
GLY A 725
THR A 746
 None
 1.24A 4mmaA-4btpA:
1.8		 4mmaA-4btpA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 10 PRO A 650
ALA A 648
TYR A 638
GLY A 716
GLY A 725
 None
 0.76A 4mmdA-4btpA:
undetectable		 4mmdA-4btpA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 10 PRO A 650
VAL A 636
ALA A 648
TYR A 638
GLY A 725
 None
 0.90A 4mmdA-4btpA:
undetectable		 4mmdA-4btpA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 PRO A 650
ALA A 648
TYR A 638
GLY A 716
GLY A 725
 None
 0.79A 4mmdB-4btpA:
1.9		 4mmdB-4btpA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 PRO A 650
VAL A 636
ALA A 648
TYR A 638
GLY A 725
 None
 0.92A 4mmdB-4btpA:
1.9		 4mmdB-4btpA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 ALA A 610
THR A 423
ILE A 425
LEU A 593
ILE A 607
 None
 1.08A 4nx6A-4btpA:
undetectable		 4nx6A-4btpA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 ALA A 610
THR A 423
ILE A 425
LEU A 593
ILE A 607
 None
 1.05A 4nx7A-4btpA:
undetectable		 4nx7A-4btpA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 ALA A 610
THR A 423
ILE A 425
LEU A 593
ILE A 607
 None
 1.05A 4pstA-4btpA:
undetectable		 4pstA-4btpA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 ALA A 610
THR A 423
ILE A 425
LEU A 593
ILE A 607
 None
 1.07A 4pthA-4btpA:
undetectable		 4pthA-4btpA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 VAL A 458
ALA A 392
LEU A 446
GLY A 687
ASP A 691
 None
 1.19A 4qckA-4btpA:
undetectable		 4qckA-4btpA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 MET A 453
GLU A 457
LEU A 461
 None
 0.69A 4v2oB-4btpA:
undetectable		 4v2oB-4btpA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_C_CLQC1079_0
(SAPOSIN-B)		 4btp P1
(Pseudomonas
phage
phi8) 		4 / 5 ARG A 464
MET A 453
GLU A 457
LEU A 461
 None
 1.39A 4v2oA-4btpA:
1.5
4v2oC-4btpA:
0.4		 4v2oA-4btpA:
7.57
4v2oC-4btpA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 10 GLY A 376
THR A 488
VAL A 378
LEU A 497
LEU A 570
 None
 0.91A 4yb6A-4btpA:
undetectable
4yb6E-4btpA:
undetectable		 4yb6A-4btpA:
18.11
4yb6E-4btpA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 10 LEU A 497
LEU A 570
GLY A 376
THR A 488
VAL A 378
 None
 0.93A 4yb6B-4btpA:
undetectable
4yb6F-4btpA:
undetectable		 4yb6B-4btpA:
18.11
4yb6F-4btpA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 LEU A 256
ILE A 307
GLY A 311
ARG A 254
ALA A 260
 None
 1.12A 5h5fA-4btpA:
undetectable		 5h5fA-4btpA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 11 VAL A 510
SER A 509
ASP A 501
TYR A 515
LEU A 567
 None
 1.24A 5jh7B-4btpA:
undetectable		 5jh7B-4btpA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 11 SER A 509
ASP A 501
TYR A 515
PRO A 566
LEU A 567
 None
 1.41A 5jh7D-4btpA:
undetectable		 5jh7D-4btpA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 11 VAL A 510
SER A 509
ASP A 501
TYR A 515
LEU A 567
 None
 1.21A 5jh7D-4btpA:
undetectable		 5jh7D-4btpA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 TRP A  39
LEU A 293
PHE A 527
PHE A  32
VAL A 525
 None
 1.36A 6a93B-4btpA:
undetectable		 6a93B-4btpA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 VAL A 176
SER A 175
THR A 174
LEU A  78
VAL A  74
 None
 1.20A 6a93B-4btpA:
undetectable		 6a93B-4btpA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 4btp P1
(Pseudomonas
phage
phi8) 		3 / 3 PHE A 472
ASP A 683
LYS A 686
 None
 0.75A 6awtD-4btpA:
undetectable		 6awtD-4btpA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 LEU A 190
ALA A  40
LEU A 294
THR A 295
LEU A 285
 None
 0.93A 6b0cD-4btpA:
undetectable		 6b0cD-4btpA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 PHE A 193
ALA A  37
ILE A 503
LEU A 293
PRO A 505
 None
 1.19A 6b3aA-4btpA:
undetectable		 6b3aA-4btpA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 PHE A 193
ALA A  37
ILE A 503
LEU A 293
PRO A 505
 None
 1.17A 6b3bA-4btpA:
undetectable		 6b3bA-4btpA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 4btp P1
(Pseudomonas
phage
phi8) 		5 / 12 ILE A 289
LEU A 285
PHE A 366
ASP A 191
ILE A 503
 None
 1.39A 6dwnB-4btpA:
undetectable		 6dwnB-4btpA:
6.82